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Anesth Analg 2003;96:1409-1412
© 2003 International Anesthesia Research Society


PAIN MEDICINE

The Effect of Clonidine on Gastrointestinal Side Effects Associated with Ultra-Rapid Opioid Detoxification

Hong Ma, PhD MD*, Jun Tang, MD*, Paul F. White, PhD MD, FANCZA*, Ronald H. Wender, MD{dagger}, Thomas Leverone, MD{ddagger}, Rayond Quon{dagger}, Scott Pearce, MD{dagger}, Franklin Chiao{dagger}, and Susan Erice, RN{ddagger}

*Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, Texas; Department of Anesthesiology, {dagger}Cedars-Sinai Medical Center; and {ddagger}Centinela Hospital Medical Center, Los Angeles, California

Address correspondence to Dr. Paul F. White, Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, F2.208, Dallas, TX 75390-9068. Address e-mail to paul.white{at}utsouthwestern.edu

IMPLICATIONS: Clonidine, an {alpha}2-adrenergic agonist, is used to minimize withdrawal symptoms related to ultra-rapid opioid detoxification procedures. These preliminary data suggest that clonidine possesses dose-related antidiarrheal activity.




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Anesth. Analg.Home page
P. Kienbaum, J. Peters, N. Scherbaum, P. F. White, and R. H. Wender
Convincing Effects of Clonidine on Neurohumoral Withdrawal Symptoms During Antagonist-Supported Detoxification of Opioid Addicts * Response
Anesth. Analg., November 1, 2003; 97(5): 1547 - 1548.
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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2003 by the International Anesthesia Research Society.