Anesth Analg 2003;96:1413-1414
© 2003 International Anesthesia Research Society
PAIN MEDICINE
Large-Dose Intravenous Methotrexate-Induced Cutaneous Toxicity: Can Oral Magnesium Oxide Reduce Pain?
Santhanam Suresh, MD*, ,
Sara Lozono, MD , and
Steven C. Hall, MD*,
Department of *Pediatric Anesthesiology, Childrens Memorial Hospital, and
Department of Anesthesiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; and
Division of Anesthesiology, The Cleveland Clinic Foundation, Cleveland, Ohio
Address correspondence and reprint requests to Santhanam Suresh, MD, Department of Pediatric Anesthesiology, Childrens Memorial Hospital, Box 19, 2300 Childrens Plaza, Chicago, IL 60614. Address e-mail to ssuresh{at}northwestern.edu
IMPLICATIONS: Chemotherapy for cancer is associated with pain including cutaneous vasculitis. Magnesium, an N-methyl-D-aspartic acid-receptor antagonist, was used successfully to treat an adolescent with pain caused by cutaneous vasculitis secondary to methotrexate therapy.
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