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Anesth Analg 2003;97:471-474
© 2003 International Anesthesia Research Society

ANESTHETIC PHARMACOLOGY

Intraocular Pressure Changes During Laparoscopy in Patients Anesthetized with Propofol Total Intravenous Anesthesia Versus Isoflurane Inhaled Anesthesia

Hany A. Mowafi, MB Bch, MSc, MD*, Abdulmohsin Al-Ghamdi, MD*, and Adel Rushood, MD{dagger}

Departments of *Anesthesia and {dagger}Ophthalmology, Faculty of Medicine, King Faisal University, Dammam, Saudi Arabia

Address correspondence and reprint requests to Dr. Hany A. Mowafi, Anesthesiology Department, King Fahd University Hospital, PO Box 40081, Al-Khobar 31952, Saudi Arabia. Address e-mail to hany_mowafi{at}hotmail.com

We examined intraocular pressure (IOP) changes during gynecologic laparoscopy performed under either thiopental-isoflurane anesthesia or total IV propofol anesthesia. Forty adult women with no preexisting eye disease scheduled for gynecologic CO2 insufflation laparoscopy were included in the study. Heart rate, mean arterial blood pressure, peak and plateau airway pressure, ETCO2, and IOP (using a Schioetz tonometer) were measured at defined intervals during the procedure. IOP decreased significantly after the induction of anesthesia in both groups, and remained so throughout the procedure in the propofol group. In the isoflurane group, however, IOP was increased significantly above the preinduction level after pneumoperitoneum with head-down position. There was no correlation between IOP and blood pressure or airway pressure. In conclusion, propofol total IV anesthesia may be a better choice for laparoscopic surgery should control of IOP be a concern.

IMPLICATIONS: In this study, we examined the effect of two anesthetic techniques on the intraocular pressure changes during laparoscopic surgery in healthy subjects. Propofol IV anesthesia protected against increases in intraocular pressure with pneumoperitoneum and head-down position.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2003 by the International Anesthesia Research Society.