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Anesth Analg 2004;98:469-470
© 2004 International Anesthesia Research Society
doi: 10.1213/01.ANE.0000096184.32247.D0

CRITICAL CARE AND TRAUMA

The Presence of Working Memory Without Explicit Recall in a Critically Ill Patient

Mehmet S. Ozcan, MD, and Dietrich Gravenstein, MD

From the Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida

Address correspondence to Mehmet S. Ozcan, MD, Department of Anesthesiology, University of Florida College of Medicine, PO Box 100254, Gainesville, FL 32610–0254. Address email to Ozcanms{at}anest1.anest.ufl.edu

We describe an intubated patient sedated with propofol who interacted with caregivers, demonstrating intact "working memory." When neuromuscular blockade and bispectral index (BIS) monitoring were instituted, a greatly reduced amount of sedative achieved BIS values less than 60. Neither the sedation that allowed working memory nor the lighter sedation that produced BIS values less than 60 resulted in recall. This experience suggests that working memory demonstrated when BIS values are less than 60 is unlikely to lead to recall.

IMPLICATIONS: The presence of intact working memory during sedation is a poor predictor of explicit recall when bispectral index values are maintained less than 60.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2004 by the International Anesthesia Research Society.