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OBSTETRIC ANESTHESIA

Worsening of Neurologic Symptoms After Epidural Anesthesia for Labor in a Guillain-Barré Patient

Sandrine Wiertlewski, MD^*,, Armelle Magot, MD^*, Sophie Drapier, MD, Jean-Marc Malinovsky, MD PhD, and Yann Péréon, MD PhD^*

*Laboratoire d’Explorations Fonctionnelles, the Clinique Neurologique, and the Département d’Anesthésie et Réanimation Chirurgicale, University Hospital, Nantes, France

Address correspondence and reprint requests to Dr. Sandrine Wiertlewski, Clinique Neurologique, Hôpital Guillaume et René Laënnec, F-44093 Nantes Cedex, France. Address email to sandrine.wiertlewsky{at}chu-nantes.fr

We report the case of a pregnant woman presenting with Guillain-Barré syndrome in which her neurologic status worsened immediately after delivery under epidural analgesia. We believe that the anesthetic technique may have played a role in the disease progression. Because of this potential association, the risks of worsening neurologic status after regional anesthesia and alternative analgesia options should be discussed with the parturient.

IMPLICATIONS: Because of the potential interaction between regional anesthesia and Guillain-Barré syndrome in pregnant women, the risks of worsening neurologic status and alternative analgesia options should be discussed with the parturient.

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