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Anesth Analg 2004;99:227-229
© 2004 International Anesthesia Research Society
doi: 10.1213/01.ANE.0000121347.11127.99

CRITICAL CARE AND TRAUMA

Respiratory Distress After Intrathecal Baclofen Withdrawal

Juan Santiago-Palma, MD, E. Daniela Hord, MD, Ricardo Vallejo, MD PhD, Jason Trella, and Shihab U Ahmed, MD

Massachusetts General Hospital Pain Center, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts

Address correspondence and reprint requests to Juan Santiago Palma, 1362 Carlton Drive, Glendale, CA 91205. Address email to jsantiagopalma{at}hotmail.com

We present the case of a 19-yr-old woman with a history of generalized dystonia who developed sudden onset of adductor spasms of the vocal cords and increased dystonia after the interruption or intrathecal baclofen therapy. Her symptoms resolved after intrathecal baclofen was restored. In patients with dystonia receiving intrathecal baclofen therapy, the onset of dyspnea associated with increased muscle tone should prompt the investigation of baclofen withdrawal.

IMPLICATIONS: A 19-yr-old woman with dystonia developed adductor spasms of the vocal cords after the interruption of intrathecal baclofen. Her symptoms resolved after intrathecal baclofen was restored. In patients with dystonia receiving intrathecal baclofen, the onset of dyspnea should prompt the investigation of baclofen withdrawl.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2004 by the International Anesthesia Research Society.