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Anesth Analg 2004;99:593-594
© 2004 International Anesthesia Research Society
doi: 10.1213/01.ANE.0000123011.00161.C9

REGIONAL ANESTHESIA

Seizures After a Bier Block with Clonidine and Lidocaine

Shihab U. Ahmed, MB BS, MPH, Ricardo Vallejo, MD PhD, and E. Daniela Hord, MD

Massachusetts General Hospital Pain Center, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts

Address correspondence and reprint requests to Shihab U. Ahmed, MD, Massachusetts General Hospital Pain Center, WACC-324, Massachusetts General Hospital, 15 Parkman St., Boston, MA 02114. Address e-mail to sahmed{at}partners.org

A 47-yr-old man with history of complex regional pain syndrome type 1 underwent an IV Bier block with a mixture of lidocaine and clonidine. The tourniquet was deflated after 60 min, and approximately 10 min later he presented with complex partial seizures. The possible mechanisms for this are discussed, and the effects of clonidine, lidocaine, and the mixture of both are reviewed, as are four additional published cases reporting seizures after the administration of clonidine.

IMPLICATIONS: Clonidine is being used increasingly as an adjuvant medication for neuropathic pain and to improve the duration of regional anesthesia. Four cases of seizures associated with the use of clonidine have been reported. We present a case of seizure after a Bier block with lidocaine and clonidine in a patient with complex regional pain syndrome type I.




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 Anesth. Analg.Home page
S. U. Ahmed, R. Vallejo, and E. D. Hord
Seizures After a Bier Block with Clonidine and Lidocaine: Is Clonidine Really the Culprit?
Anesth. Analg., September 1, 2005; 101(3): 924 - 924.
[Full Text] [PDF]

Home page
 Anesth. Analg.Home page
S. Datta, U. Pai, P. O. Bridenbaugh, and A. Walia
Seizures After a Bier Block with Clonidine and Lidocaine: Is Clonidine Really the Culprit?
Anesth. Analg., September 1, 2005; 101(3): 923 - 924.
[Full Text] [PDF]


Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2004 by the International Anesthesia Research Society.