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AMBULATORY ANESTHESIA

Does Benzydamine Hydrochloride Applied Preemptively Reduce Sore Throat Due to Laryngeal Mask Airway?

Ismail Kat, MD, Murat Tekin, MD, Emin Silay, MD, Urfettin A. Huseyinoglu, MD, and Huseyin Yldz, MD

Department of Anesthesiology, Medical Faculty, Yuzuncu Yl University, Van, Turkey

Address correspondence and reprint requests to Ismail Kat, MD, YÜzÜncÜ Yl Üniversitesi, Tp FakÜltesi Anesteziyoloji AD, 65300 Van, Turkey. Address e-mail to ismaikati{at}hotmail.com

Sore throat is a common postoperative complaint. We investigated whether preemptive benzydamine hydrochloride (BH) treatment could prevent sore throat due to a laryngeal mask airway (LMA) cuff inflated with air. One-hundred ASA status I–II patients who underwent general anesthesia were randomly divided into two groups. In the first group, four puffs of BH were applied to the pharynx 30 min before the operation and 5 min before the induction of anesthesia. Distilled water with a similar bottle was applied with the same protocol in the second group. Anesthetic induction was provided with propofol and fentanyl. The pressure of the LMA cuff inflated with room air was measured after the first adjustment and after 30, 60, and 90 min of inflation in both groups. At the end of operation, the LMA was removed after the recovery of spontaneous breathing. After the operation, patients were asked about sore throat symptoms at the first, second, and fourth hours. There were no significant differences between groups for cuff pressures, cuff volumes, analgesic doses, or operation times. However, sore throat symptoms were significantly less severe for the BH group during both resting and swallowing. In conclusion, preemptive topical BH may decrease the incidence of sore throat due to LMA use.

IMPLICATIONS: We investigated whether preemptive benzydamine hydrochloride (BH) treatment could prevent sore throat due to a laryngeal mask airway (LMA) cuff inflated with air. We conclude that preemptive topical BH treatment may prevent sore throat due to LMA use.

This article has been cited by other articles:

				A. Agarwal, S. S. Nath, D. Goswami, D. Gupta, S. Dhiraaj, and P. K. Singh An Evaluation of the Efficacy of Aspirin and Benzydamine Hydrochloride Gargle for Attenuating Postoperative Sore Throat: A Prospective, Randomized, Single-Blind Study Anesth. Analg., October 1, 2006; 103(4): 1001 - 1003. [Abstract] [Full Text] [PDF]

Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999