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Anesth Analg 2005;100:94-96
© 2005 International Anesthesia Research Society
doi: 10.1213/01.ANE.0000140951.65240.94


AMBULATORY ANESTHESIA

Peribulbar Anesthesia: A Percutaneous Single Injection Technique with a Small Volume of Anesthetic

Leonardo Rizzo, MD*, Maurizio Marini, MD*, Chiara Rosati, MD*, Italo Calamai, MD*, Michela Nesi, MD*, Roberto Salvini, MPH{dagger}, Cinzia Mazzini, MD{ddagger}, Fiamma Campana, MD{ddagger}, and Enzo Brizzi, MD§

*Department of Critical Care Medicine and Surgery, Section of Anesthesiology, {dagger}Department of Epidemiology, {ddagger}Department of Oto-Neuro-Ophthalmological Surgery, Section of Ophthalmology, §Department of Pathologic Anatomy, University of Florence, Florence, Italy

Address correspondence and reprint requests to Leonardo Rizzo, MD, Department of Critical Care Medicine and Surgery, Section of Anesthesiology, University of Florence, Viale Morgagni 85, 50134, Florence, Italy. Address email to leonardorizzo{at}inwind.it


    Abstract
 Top
 Abstract
 Introduction
 Methods
 Results
 Discussion
 References
 
We evaluated the efficacy and safety of a single injection technique with a small volume of anesthetic for ocular peribulbar anesthesia. We included 857 patients undergoing various ophthalmic procedures. Anesthesia consisted of a medial percutaneous injection of 5–6.5 mL of 2% lidocaine. At 2 min 85.6% of the patients had a motor block of at least 50% and at 5 min 78.6% had a motor block >80%. After 5 min 100% of the patients had adequate surgical anesthesia. There were no serious block-related complications. The described technique is a simple and satisfactory alternative to the classical techniques

IMPLICATIONS: Potential complications associated with regional anesthesia in ophthalmic surgery led to the proposal of a single, rather than multiple, injection technique of regional anesthesia. The described percutaneous peribulbar medial single injection technique with very small volume of anesthetic is a simple and satisfactory alternative to the classical techniques.


    Introduction
 Top
 Abstract
 Introduction
 Methods
 Results
 Discussion
 References
 
Ophthalmic procedures such as cataract extraction with phacoemulsification can be performed with either topical or regional anesthesia (1). Regional anesthesia is still widely used in cases of difficult surgery and extended time surgery (1).

Retrobulbar anesthesia is the standard technique for regional anesthesia in ophthalmic surgery, but complications of this technique, although relatively uncommon, can be catastrophic. However, the complications associated with retrobulbar anesthesia have been subsequently described with peribulbar anesthesia with less, but still unacceptable, frequency (2–7).

An overview of the ASA Closed Claims Project database reported that the most common disabling injuries associated with regional anesthesia are related to nerve blocks of the eye (8). These potential risks led to the proposal of a single, rather than multiple, injection technique of peribulbar and episcleral anesthesia in order to decrease the risks of complications (9–12).

The purpose of this study was to evaluate the efficacy and safety of a percutaneous peribulbar single injection technique of regional anesthesia with a small volume of anesthetic for various ophthalmic procedures.


    Methods
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 Abstract
 Introduction
 Methods
 Results
 Discussion
 References
 
The study was conducted after approval of our institution’s local ethics committee and patients’ verbal, informed consent. Eight-hundred-fifty-seven consecutive patients scheduled for elective ophthalmic procedures at Department of Oto-Neuro-Ophthalmological Surgery, Section of Ophthalmology, University of Florence from September 2001 to March 2003 were included. Exclusion criteria were contraindications to ocular regional anesthesia and patient refusal. The patients were not fasted. A few uncooperative patients (approximately 8%) were premedicated with midazolam IV (0.02 mg/kg) 5 min before the block. All patients had a peripheral IV line inserted and the usual standard monitoring was used.

Anesthetic Technique
The injections were given with a 25-gauge, 16-mm bevel disposable needle. The anesthetic was 2% lidocaine; volume ranged from 5 to 6.5 mL on the basis of dimension of the eye socket. The patients were asked to move their eye so as to expose the area to be injected (to 10 o’clock for right eye and to 2 o’clock for left eye).

The injection site was percutaneous and limited superiorly from inferior lacrimal canaliculus, median from lateral margin of nose, laterally from imaginary perpendicular line that join inferior lacrimal papilla to inferior margin of orbit and inferiorly from inferior margin of orbit (Fig. 1).



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Figure 1. Entry site of the needle for regional anesthesia techniques. 1 = semilunaris fold; 2 = caruncle; 3 = entry site for our percutaneous injection technique; 4 = entry site for episcleral anesthesia; 5 = entry site for peribulbar anesthesia.

 
The needle was advanced percutaneously in an antero-posterior direction for half of its length (never more than 10 mm) (Fig. 2a) and later obliquely in the direction of the optical foramen until the needle was on the same plane of the bony margin of orbit (Fig. 2b). After aspiration, the anesthetic was injected in approximately 30 s.



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Figure 2. A, the needle was advanced percutaneously in an antero-posterior direction for half of its length. B, the needle was advanced obliquely in the direction of optical foramen until the needle was on the same plane of the bony margin of orbit.

 
An initial transient fullness in the supero-internal region of superior lid was predictive of successful blockade. After the needle was removed, moderate digital massage of the eyeball and compression of the site of injection were performed. Patients were observed carefully during the injection and immediate complications were noted.

Akinesia of the globe and eyelids was assessed at 2 min (T1) and 5 min (T2). A 12-point scale (13) was used (each of the 4 rectus muscles and each lid was scored from 0 to 2; 0 = no block, 1 = partial akinesia, 2 = total akinesia).


    Results
 Top
 Abstract
 Introduction
 Methods
 Results
 Discussion
 References
 
Five-hundred-forty-two female (mean age 72 ± 11 yr) and 315 male (mean age 70 ± 12 yr) patients (ASA physical status I–III) were studied. The procedures were 517 phacoemulsifications and posterior chamber artificial lens implantations, 137 open globe procedures for lens extraction (intracapsular or manual extracapsular extraction), 109 trabeculectomies, and 94 other procedures including vitrectomy and retinal surgery.

At T1 85.6% of patients had a motor block of at least 50% (score 6 of 12) and at T2 78.6% of patients had a motor block >80% (score 8 of 12). After 7 min 100% of patients had adequate anesthesia to proceed with and complete the surgery. Only 107 patients required midazolam 0.015 mg/kg intraoperatively.

Complications included one case of inferior lid hematoma for perforation of a superficial vein tributary of the angular vein and four cases of chemosis that did not hinder surgery. There were no cases of perforation of the globe, retinal or optic nerve damage or orbital hematoma or postoperative diplopia.


    Discussion
 Top
 Abstract
 Introduction
 Methods
 Results
 Discussion
 References
 
In this large series of patients peribulbar anesthesia by a medial percutaneous single injection was a valid alternative technique for ocular regional anesthesia because of the infrequent complications we observed. This site of injection is relatively avascular, which may decrease the risk of hematoma. Indeed, we noted no orbital hematoma in this series. Because the insertion of the needle is limited to the anterior orbit, ophthalmic artery, optic nerve or retinal injury is unlikely. It should be stressed that akinesia and analgesia of the globe and eyelid were obtained with our technique using a very small volume of anesthetic (no more than 6.5 mL).

To determine the exact pattern of distribution of anesthetic fluid in this type of regional anesthesia in 27 patients we performed B-scan ultrasonography before (Fig. 3, left) and at few minutes (Figs. 3, right, and 4) after the administration of anesthetic (14). After the injection, the fluid tracked behind the globe in the sub-Tenon capsule space (Fig. 4, left). Posterior, the fluid around the optic nerve developed a characteristic T sign (Fig. 4, right). The fascial sheath of the eyeball (Tenon’s capsule) is a fibrous layer that surrounds the eyeball from the optic nerve to the corneal ring. It is a thick membrane at the equator of the globe, where it is pierced by the rectus muscle tendons and is continued by the muscle sheaths. The episcleral space is a virtual gliding space between the sclera and the fascial sheath of the eyeball. The sensitivity of the eyeball is provided by the ciliary nerves, which cross the episcleral space after they emerge from the globe. We confirmed that a small volume of local anesthetic (5–6.5 mL) injected in this space is guided to surround the eyeball and produce analgesia. The fascial sheath of the eyeball extends to the rectus muscle sheaths. This explains why the anesthetic is preferentially guided to those muscle sheaths to produce good akinesia. Furthermore the fascial sheath of the eyeball guides the injected solution to the lids, especially to the orbicularis muscle. This explains how we can prevent blinking during surgery without performing any facial nerve block.



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Figure 3. B-scan ultrasonography. Left, before the block. Right, white arrows show orbital fat infiltrated by anesthetic (dark zone). MRM = medial rectus muscle.

 


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Figure 4. B-scan ultrasonography. Left, Subtenonian space (arrows) dilated by anesthetic in retrobulbar space after a few minutes. Right, "T sign" (green lines) formed by optic nerve shadow crossing subtenonian space. ON = optic nerve.

 
Our medial single injection technique is a simple and satisfactory alternative approach for ocular regional anesthesia. The advantages include decreased pain with percutaneous and short needle insertion, decreased volume of anesthetic, single rather than multiple punctures, puncture in a relatively avascular area, and a needle path that is less subject to misdirection.


    References
 Top
 Abstract
 Introduction
 Methods
 Results
 Discussion
 References
 

  1. Crandall AS. Anesthesia modalities for cataract surgery. Curr Opin Ophthalmol 2001; 12: 9–11.[Medline]
  2. Grizzard WS, Kirk NM, Pavan PR, et al. Perforating ocular injuries caused by anesthesia personnel. Ophthalmology 1991; 98: 1011–6.[Web of Science][Medline]
  3. Edge R, Navon S. Scleral perforation during retrobulbar and peribulbar anesthesia: risk factor and outcome in 50,000 consecutive injections. J Cataract Refract Surg 1999; 25: 1237–44.[Medline]
  4. Troll GF. Regional ophthalmic anesthesia: safe techniques and avoidance of complications. J Clin Anesth 1995; 7: 163–72.[Medline]
  5. Lichter PR. Avoiding complications from local anesthesia. Ophthalmology 1988; 95: 565–6.[Web of Science][Medline]
  6. Davis DB, Mandel MR. Efficacy and complication rate of 16224 consecutive peribulbar blocks: a prospective multicenter study. J Cataract Refract Surg 1994; 20: 327–37.[Web of Science][Medline]
  7. Lee MS, Rizzo JF III, Lessell S. Neuro-ophthalmologic complications of cataract surgery. Semin Ophtalmol 2002; 17: 149–52.
  8. Ben-David B. Complications of regional anaesthesia: an overview. Anesthesiol Clin N Am 2002; 20: 665–7.[Medline]
  9. Ripart J, Metge L, Prat-Pradal D, et al. Medial canthus single-injection episcleral (sub-Tenon anesthesia): computed tomography imaging. Anesth Analg 1998; 87: 42–5.[Abstract/Free Full Text]
  10. Ripart J, Lefrant JY, L’Hermite JI, et al. Caruncle single injection episcleral (sub-Tenon) anesthesia for cataract surgery: mepivacaine versus a lidocaine-bupivacaine mixture. Anesth Analg 2000; 91: 107–9.[Abstract/Free Full Text]
  11. Ripart J, Lefrant JY, Vivien B et al. Ophthalmic regional anesthesia: medial canthus episcleral (sub-Tenon) anesthesia is more efficient than peribulbar anesthesia: a double-blind randomized study. Anesthesiology 2000; 92: 1278–85.[Medline]
  12. Dareau S, Gros T, Bassoul B, et al. Orbital haemorrhage after medial canthus episclera (sub-Tenon’s) anaesthesia. Ann Fr Anesth Reanim 2003; 22: 474–6.[Medline]
  13. Ripart J, Lefrant JY, Lalourcey L, et al. Medial canthus (caruncle) single injection periocular anesthesia. Anesth Analg 1996; 83: 1234–8.[Abstract]
  14. Winder S, Walker SB, Atta HR. Ultrasonic localization of anesthetic fluid in sub-Tenon’s, peribulbar, and retrobulbar techniques. J Cataract Refract Surg 1999; 25: 56–9.[Web of Science][Medline]
Accepted for publication July 16, 2004.





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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 2005 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press