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Anesth Analg 2007;104:745
© 2007 International Anesthesia Research Society
doi: 10.1213/01.ane.0000256025.95981.c5


LETTER TO THE EDITOR

Section Editor:
Lawrence Saidman

The Safety and Efficacy of Spinal Anesthesia for Surgery in Infants

Robert K. Williams, MD, J. Christian Abajian, MD, and David C. Adams, MD

Departments of Anesthesia and Pediatrics; College of Medicine, University of Vermont; Burlington, Vermont; Robert.Williams{at}vtmednet.org

In Response:

We thank Dr. Mayhew (1) for his comments on our study (2) and agree that spinal anesthesia appears to be underutilized for otherwise appropriate surgical procedures in infants.

Although we acknowledge that the relatively short duration of action of spinal anesthetics in infants may ultimately limit its utility, the minimal expected duration of surgical anesthesia typically ranges from 60 to 90 min (3). The duration of neuraxial blockade may be further prolonged by using a combined spinal/epidural technique, or by the addition of intrathecal clonidine (4,5). In our patients (2), the duration of tetracaine spinal anesthesia was sufficient for a variety of surgical procedures performed by numerous surgeons and trainees. The need to convert to general anesthesia because of insufficient duration of anesthesia was just 1.2%.

The administration of supplemental sedation increases the risk of postoperative apnea. For this reason we prefer soothing and stroking our patients to pharmacological sedation, and most of our patients (76%) did not require supplemental sedation. The use of sedation does not negate the other beneficial aspects of the technique. When compared with general anesthesia, spinal anesthesia is associated with a dramatic decrease in the incidence of postoperative hypoxia, bradycardia, and hypotension (6). Even though infants are notorious for respiratory complications, the vast majority of our infants (96%), underwent the entire surgical process from start to finish breathing room air, and oxyhemoglobin desaturation was extremely rare (<0.6%).

Over the past two decades, more than 1500 infants underwent surgery in our institution without requiring active airway management. The cardiovascular and respiratory stability of infant spinal anesthesia is compelling. We endorse Dr. Mayhew’s call for a national survey to identify the barriers that impede widespread use of infant spinal anesthesia.

REFERENCES

  1. Mayhew JF. The safety and efficacy of spinal anesthesia for surgery in infants. Anesth Analg 2006;104:745.
  2. Williams RK, Adams DC, Aladjem EV, et al. The safety and efficacy of spinal anesthesia for surgery in infants: the Vermont infant spinal registry. Anesth Analg 2006;102:67–71.[Abstract/Free Full Text]
  3. Polaner D, Suresh S, Cote C. Pediatric regional anesthesia. In: Cote C, ed. A practice of anesthesia for infants and children. Philadelphia: WB Saunders, 2001;646.
  4. Williams R, McBride W, Abajian JC. Combined spinal and epidural anesthesia for major abdominal surgery in infants. Can J Anaesth 1997;44:511–14.[Abstract/Free Full Text]
  5. Rochette A, Raux O, Troncin R, et al. Clonidine prolongs spinal anesthesia in newborns: a prospective dose-ranging study. Anesth Analg 2004;98:56–9.[Abstract/Free Full Text]
  6. Krane E, Haberkern C, Jacobson L. Postoperative apnea, bradycardia and oxygen desaturation in formerly premature infants: prospective comparison of spinal and general anesthesia. Anesth Analg 1995;80:7–13.[Abstract]




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press