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LETTER TO THE EDITOR

Hemostatic Impairment After Infusion of Hydroxyethyl Starch, Gelatin, and Albumin

Department of Anesthesiology and Intensive Care Medicine, Helsinki University Hospital, Meilahti Hospital, Helsinki, Finland, tomi.niemi{at}hus.fi

In Response:

Drs. Bamgbade, Dorje, and Caldwell (1) raise an interesting question about whether our results (2) varied with patient blood type. Unfortunately, we do not have ready access to ABO blood types in our patients, although this could probably be determined from reviewing the preoperative laboratory studies. The greater concern is that our sample size was relatively small. As a result, I don’t expect that we would have enough sensitivity to identify the different effects of blood type on the hemostatic alterations associated with synthetic colloid solutions.

REFERENCES

1. Bamgbade O, Dorje P, Caldwell M. Hemostatic Impairment After Infusion of Hydroxyethyl Starch, Gelatin, and Albumin. Anesth Analg 2007;104:1295–6.[Free Full Text]
2. Niemi T, Suojaranta-Ylinen RT, Kukkonen SI, Kuitunen AH. Gelatin and hydroxyethyl starch, but not albumin, impair hemostasis after cardiac surgery. Anesth Analg 2006; 102:998–1006.[Abstract/Free Full Text]

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