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Anesth Analg 2007;105:543-544
© 2007 International Anesthesia Research Society
doi: 10.1213/01.ane.0000265696.16017.c5


LETTER TO THE EDITOR

Section Editor:
Lawrence Saidman

Is the Hemodynamic Response to Nasotracheal Fiberoptic Bronchoscopy Less Than That Following Orotracheal Bronchoscopy?

Fu Shan Xue, MD, Cheng Wen Li, MD, Kun Peng Liu, MD, Hai Tao Sun, MD, Guo Hua Zhang, MD, Ya Chao Xu, MD, and Yi Liu, MD

Department of Anaesthesiology; Plastic Surgery Hospital; Chinese Academy of Medical Sciences and Peking Union Medical College; Beijing; People’s Republic of China; fruitxue{at}yahoo.com.cn

In Response:

We appreciate the comments presented by Adachi et al. (1), but we do not concur with their comment that same depth of anesthesia was not maintained in our study. The anesthetic protocol used in all of our studies was as follows: After routine preoxygenation anesthesia was induced with fentanyl 2 µg/kg and propofol 2.5 mg/kg IV over 15–20 s, neuromuscular block was produced with vecuronium 0.1 mg/kg IV. When a response to verbal command was absent, the lungs were ventilated via a facemask with isoflurane and 100% oxygen. The inspired concentration of isoflurane was gradually increased to 1% with an increment of 0.2% every four breaths. After tracheal intubation, anesthesia was maintained with isoflurane and 60% nitrous oxide in oxygen. During the observation, a fresh gas flow of 1.5 L/min was used, and the ventilator settings and isoflurane concentrations adjusted to maintain end-expired carbon dioxide and isoflurane concentrations of 35–40 mm Hg and 1%, respectively. Inspired and end-tidal concentrations of isoflurane, oxygen, nitrous oxide, and carbon dioxide were measured and displayed digitally with a multifunction monitor ®Datex Ohmeda F-CU8©. In addition, all anesthetics were given by the same anesthetist in each study, and comparable anesthetic equipment and drugs that are produced in a single factory and have the same batch number were used in all cases. These methods were described in detail in the Discussion section of our article (2). Before publication of our manuscript, however, details of the anesthetic protocol described above were deleted by the editors to shorten the length of the text.

REFERENCES

  1. Adachi YU, Suzuki K, Obata Y, Doi M, Sato S. Is the hemodynamic response to nasotracheal fiberoptic bronchoscopy less than that following orotracheal bronchoscopy? Anesth Analg 2007;105:543[Free Full Text]
  2. Xue FS, Li CW, Sun HT, Liu KP, Zhang GH, Xu YC, Liu Y, Yu L. Circulatory responses to fibreoptic intubation in anesthetized children: a comparison of oral and nasal routes. Anesth Analg 2007;104:283–8[Abstract/Free Full Text]




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 2007 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press