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Anesth Analg 2008; 106:1922-
© 2008 International Anesthesia Research Society
doi: 10.1213/ane.0b013e318172c996
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LETTER TO THE EDITOR

Section Editor:
Lawrence Saidman

Avoiding Emetogenic Triggers in the First Place Is More Effective than Using Antiemetics

Tong J. Gan, T. Meyer, C. C. Apfel, F. Chung, P. J. Davis, A. S. Habib, V. Hooper, A. Kovac, P. Kranke, P. Myles, B. Philip, G. Samsa, D. I. Sessler, J. Temo, M. R. Tramèr, C. Vander Kolk, and M. Watcha

Department of Anesthesiology; Duke University Medical Center; Durham, North Carolina; gan00001{at}mc.duke.edu

In Response:

The interpretation by Friedberg that the consensus panel’s emphasis was "heavily biased in favor of antiemetic therapy"1 is not consistent with the published guidelines: the panel affirms that reducing baseline risk factors are important and constitute effective strategies in reducing the risks for developing postoperative nausea and vomiting (PONV).

In the published consensus,2 Guideline 1 recommends the assessment of risks for PONV. Guideline 2 outlines strategies to reduce the baseline risks. Among the recommendations include the use of regional anesthesia with local anesthetics as well as the use of local anesthetic infiltration to reduce intraoperative and postoperative opioid requirements. This is followed by Guideline 3, which discusses the options for antiemetic pharmacotherapy. The panel believes this is a logical sequence for managing patients to prevent PONV.

REFERENCES

  1. Barry L. Friedberg. Avoiding emetogenic triggers in the first place is more effective than using antiemetics. Anesth Analg 2008;106:1921–2[Free Full Text]
  2. Gan TJ, Meyer TA, Apfel CC, Chung F, Davis PJ, Habib AS, Hooper VD, Kovac AL, Kranke P, Myles P, Philip BK, Samsa G, Sessler DI, Temo J, Tramèr MR, Vander Kolk C, Watcha M; Society for Ambulatory Anesthesia. Society for Ambulatory Anesthesia Guidelines for the management of postoperative nausea and vomiting. Anesth Analg 2007;105:1615[Abstract/Free Full Text]



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P. F. White and P. S. A. Glass
Universal PONV Prophylaxis in General Anesthesia: Should We Consider Its Immediate Implementation?
Anesth. Analg., June 1, 2008; 106(6): 1922 - 1923.
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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 2008 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press