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Anesth Analg 2008; 107:344-
© 2008 International Anesthesia Research Society
doi: 10.1213/ane.0b013e3181771097
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LETTER TO THE EDITOR

Section Editor:
: Lawrence Saidman

Smoking and Nalbuphine May Reduce Postoperative Emesis

Miriam Harnett, MB, FFARCSI, and Scott Segal, MD

Department of Anesthesia, Perioperative and Pain Medicine; Brigham and Women's Hospital; Harvard Medical School, Boston; mharnett{at}partners.org

In Response:

Apiliogullari and Duman1 highlight some important points in response to our paper.2 First, although we agree that the incidence of PONV is reduced in cigarette smokers, we did not include cigarette smoking as an exclusion criteria in our study population because it is unheard of for pregnant patients at our institution to smoke. Second, with regard to the use of ondansetron as both a study and a rescue antiemetic medication, we did comment that "some may criticize the use of ondansetron as one of the rescue antiemetic drugs in the study. Ondansetron was chosen for rescue treatment because ondansetron and metoclopramide are standard drugs for rescue treatment in our institution." Finally, there was no significant difference between the three groups (placebo, ondansetron, and scopolamine) in the use of nalbuphine as an antipruritic.

REFERENCES

  1. Apiliogullari S, Duman A. Smoking and nalbuphine may reduce postoperative emesis. Anesth Analg 2008;107:344[Free Full Text]
  2. Harnett MJP, O'Rourke N, Walsh M, Carabuena JM, Segal S. Transdermal scopolamine for prevention of intrathecal morphine-induced nausea and vomiting after cesarean delivery. Anesth Analg 2007;105:764–9[Abstract/Free Full Text]




This Article
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Right arrow Alert me when this article is cited
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PubMed
Right arrow Articles by Harnett, M.
Right arrow Articles by Segal, S.

Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 2008 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press