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Anesth Analg 1999;89:1587
© 1999 International Anesthesia Research Society


LETTERS TO THE EDITOR

Transcranial Doppler Technique for Monitoring the Efficacy of Selective Antegrade Cerebral Perfusion

Adrianus J. De Vries, MD

Department of Anesthesiology University Hospital Groningen, Groningen, The Netherlands

I would like to report on the use of transcranial Doppler (TCD) as a monitoring tool for the efficacy of selective antegrade cerebral perfusion (SACP) during circulatory arrest for surgery of the aortic arch.

A 44-yr-old man was scheduled for aortic arch reconstruction because of a large aortic aneurysm. After the induction of anesthesia a 2-MHz TCD transducer was fixated over the left middle cerebral artery. At a nasopharyngeal temperature of 20°C, the right and the left carotid artery were carefully canulated and, via a separate roller pump, perfused with a flow of 300 mL/min. At 300 mL/min, no flow was detected by TCD (Figure 1). The hemoglobin level of the perfusate was 4.2 mmol/L, and pH management during the procedure was alpha-stat. The pump flow was increased, and at a flow of 550 mL/min a stable TCD tracing suddenly appeared (Figure 2), indicating flow in the left middle cerebral artery. This flow was comparable to the flow in the middle cerebral artery on full cardiopulmonary bypass just before SACP. No embolic events were seen. After 40 min, cardiopulmonary bypass was reinstituted. The patient had an uneventful recovery without neurological sequelae.



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Figure 1. Transcranial Doppler registration of the left middle cerebral artery during selective cerebral perfusion at a flow of 300 mL/min. Three artifacts can be seen, but no flow is present.

 


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Figure 2. Transcranial Doppler registration of the left middle cerebral artery during selective cerebral perfusion at a flow of 550 mL/min. A mean flow of 12 cm/s is seen.

 
Recommended flows for SACP are approximately 300 mL/min (1,2). This was, in our patient, insufficient to produce an adequate signal on TCD. The fact that, on increasing the flow to 550 mL/min, a stable TCD signal was suddenly seen stresses the point that a certain resistance in the brain or shunting via the external carotid system has to be overcome. We therefore find the simple and noninvasive TCD measurement of the flow in the middle cerebral artery essential in assuring an adequate cerebral blood flow during SACP in the individual patient during these high-risk surgical procedures.

References

  1. Alamanni F, Agrifoglio M, Pompilio G, et al. Aortic arch surgery: pros and cons of selective cerebral perfusion: a multivariable analysis for cerebral injury during hypothermic circulatory arrest. J Cardiovasc Surg (Torino) 1995;36:31–7.[Medline]
  2. Frist WH, Baldwin JC, Starnes VA, et al. A reconsideration of cerebral perfusion in aortic arch replacement. Ann Thorac Surg 1986;42:273–81.[Abstract]



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J. Thorac. Cardiovasc. Surg.Home page
A. L. Estrera, Z. Garami, C. C. Miller III, R. Sheinbaum, T. T.T. Huynh, E. E. Porat, B. S. Allen, and H. J. Safi
Cerebral monitoring with transcranial Doppler ultrasonography improves neurologic outcome during repairs of acute type A aortic dissection
J. Thorac. Cardiovasc. Surg., February 1, 2005; 129(2): 277 - 285.
[Abstract] [Full Text] [PDF]


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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 1999 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press