Table 2. Postoperative Analgesics in Intramuscular Propoxyphene (mg/24 h Postoperatively) and IM Paracetamol (mg/24 h Postoperatively), Codeine (mg/2–10 days) and Paracetamol (mg/2–10 Days) Consumed as Lonarid® Tablets, peros Total Paracetamol (Plain and in Lonarid Tablets) (mg/2–10 Days) and peros Hydroxyzine (mg/1–10 Days) in Each Group
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Mexiletinea (n = 21)
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Gabapentin (n = 22)
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Control (n = 24)
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Significant differences
|
| Propoxyphene IM (mg), POD1 |
123 ± 54 |
119 ± 50 |
116 ± 58 |
|
| Paracetamol IM (mg), POD1 |
982 ± 436 |
954 ± 400 |
925 ± 467 |
|
| Codeine (mg) PO, POD1–10 |
55 ± 54* |
65 ± 53** |
113 ± 78 |
P = 0.029 |
| Paracetamol in Lonarid® tablets (mg) PO, POD2–10 |
2209 ± 2178 |
2600 ± 2130 |
4533 ± 3120 |
P = 0.029 |
| Total paracetamol (mg) PO, POD2–10 |
2305 ± 2176|| |
2600 ± 2130¶ |
4992 ± 3317 |
P = 0.0085 |
| Hydroxyzine (mg) PO, POD1–10 |
150 ± 219 |
59 ± 153 |
106 ± 150 |
|
|
| Values are mean ± SD. The right column indicates a group effect by Kruskal- Wallis. Data refer to the acute phase. IM = intramuscular; PO = per os; POD = postoperative day. |
| *P = 0.018, |
| P = 0.035, |
| P = 0.018, |
| P = 0.035, |
| ||P = 0.0071 |
| ¶P = 0.011, each compared with the control group. |
| a No differences were observed between mexiletine and gabapentin. |
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