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Table 2. Postoperative Analgesics in Intramuscular Propoxyphene (mg/24 h Postoperatively) and IM Paracetamol (mg/24 h Postoperatively), Codeine (mg/2–10 days) and Paracetamol (mg/2–10 Days) Consumed as Lonarid® Tablets, peros Total Paracetamol (Plain and in Lonarid Tablets) (mg/2–10 Days) and peros Hydroxyzine (mg/1–10 Days) in Each Group
 Mexiletinea (n = 21)
 Gabapentin (n = 22)
 Control (n = 24)
 Significant differences
Propoxyphene IM (mg), POD1 123 ± 54 119 ± 50 116 ± 58
Paracetamol IM (mg), POD1 982 ± 436 954 ± 400 925 ± 467
Codeine (mg) PO, POD1–10 55 ± 54* 65 ± 53**{dagger} 113 ± 78 P = 0.029
Paracetamol in Lonarid® tablets (mg) PO, POD2–10 2209 ± 2178{ddagger} 2600 ± 2130§ 4533 ± 3120 P = 0.029
Total paracetamol (mg) PO, POD2–10 2305 ± 2176|| 2600 ± 2130 4992 ± 3317 P = 0.0085
Hydroxyzine (mg) PO, POD1–10 150 ± 219 59 ± 153 106 ± 150
Values are mean ± SD. The right column indicates a group effect by Kruskal- Wallis. Data refer to the acute phase. IM = intramuscular; PO = per os; POD = postoperative day.
*P = 0.018,
{dagger}P = 0.035,
{ddagger}P = 0.018,
§P = 0.035,
||P = 0.0071
P = 0.011, each compared with the control group.
a No differences were observed between mexiletine and gabapentin.





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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press