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Anesth Analg 2003;97:715-717
© 2003 International Anesthesia Research Society


AMBULATORY ANESTHESIA

Continuous Paravertebral Catheter and Outpatient Infusion for Breast Surgery

Chester C. Buckenmaier, III, MD, Stephen M. Klein, MD, Karen C. Nielsen, MD, and Susan M. Steele, MD

Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina

Address correspondence and reprint requests to Chester C. Buckenmaier III, MD, Regional Anesthesia Section, Anesthesia & Operative Services, Walter Reed Army Medical Center, Washington, DC 20307. Address e-mail to chester.buckenmaier{at}na.amedd.army.mil


    Abstract
 Top
 Abstract
 Introduction
 Case 1
 Discussion
 Appendix A.
 References
 

IMPLICATIONS: Paravertebral somatic nerve block is an alternative to general anesthesia for breast surgery. We describe a novel needle system for paravertebral catheter insertion linked to a disposable infusion pump for prolonged analgesia at home after breast surgery.


    Introduction
 Top
 Abstract
 Introduction
 Case 1
 Discussion
 Appendix A.
 References
 
Paravertebral somatic nerve block (PVB) is an alternative to general anesthesia for breast surgery (1). It provides improved analgesia and decreased side effects (2). However, single-injection techniques are limited by the duration of the local anesthetic. Recent improvements in needle design and the introduction of disposable infusion pumps have facilitated the use of ambulatory perineural infusions after extremity surgery (3,4). Continuous perineural infusion techniques for ambulatory breast surgery have not been described. We describe two patients who underwent major breast surgery with a continuous PVB using a novel needle system. Both were discharged home the following day with a continuous infusion of local anesthetic via a disposable pump for 24 h (48-h total infusion).


    Case 1
 Top
 Abstract
 Introduction
 Case 1
 Discussion
 Appendix A.
 References
 
A 50-yr-old woman, ASA physical status II (weight 53 kg; height 157 cm) was scheduled for a right modified radical mastectomy. Her history was significant for breast cancer, tobacco use, fibromyalgia, migraine headaches, and cobalamin deficiency. Her daily oral medications included verapamil 80 mg 3 times a day, zolpidem 10 mg, cyclobenzaprine 5 mg, sertraline 50 mg each evening, and sumatriptan 50 mg as needed. Other medications included alendronate 70 mg weekly as needed and cobalamin 1000-µg injections monthly.

A PVB with an indwelling catheter and intraoperative sedation were planned. In the preoperative holding area, routine monitors were applied and supplemental oxygen was delivered via facemask. Midazolam 3 mg and fentanyl 150 µg IV were titrated for sedation.

In the sitting position using aseptic technique, the patient underwent single-injection PVB at 2 thoracic levels, T1 and T6, with 5 mL of 1% ropivacaine using the technique described by Greengrass and Steele (5). The T1 and T6 blocks were placed for complete surgical anesthesia of the breast. In our experience, these segments are inconsistently blocked with a single-injection block at T3.

For catheter placement at T3, a 25-gauge spinal needle was initially inserted to estimate depth of the T3 transverse process. An 18-gauge, 9-cm Tuohy needle attached to a hemostatic valve and sideport (B. Braun Medical Inc., Bethlehem, PA; Fig. 1), was then advanced to the transverse process (bevel up), walked off caudad, and advanced a maximum of 1 cm. A loss of resistance was noted as the needle passed through the superior costotransverse ligament into the paravertebral space. Correct needle location was further confirmed by decreased resistance to local anesthetic injection through the needle system by the assistant. After incremental injection of 20 mL of 0.5% ropivacaine, a 20-gauge, open-tipped epidural catheter was advanced 2 cm beyond the tip of the needle. The catheter was secured with medical adhesive, Steri-StripsTM, and a transparent dressing. A test dose of 5 mL of the local anesthetic solution was administered via the catheter. All local anesthetic solutions used contained epinephrine 1:400,000 as an intravascular marker.



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Figure 1. A, Paravertebral catheter equipment. The apparatus consists of an 18-gauge, 9-cm Tuohy needle (B. Braun Medical Inc.). Attached to the needle is a homostasis valve and sideport assembly with 50 cm of extension tubing that connects a 20-mL syringe with local anesthetic. B, Disposable infusion pump with 275-mL reservoir (AccufuserTM 275 10 mL/h; McKinley Medical).

 
Fifteen minutes after block placement, decreased temperature sensation in the T1-6 dermatomes was determined as an indication of successful block. The patient was then transferred to the operating room and sedated with IV propofol 25–75 µg · kg-1 · min-1. An additional 2 mg of midazolam and 100 µg of fentanyl IV were administered at the start of the surgery. An infusion of 0.2% ropivacaine at 10 mL/h (no epinephrine) via the paravertebral catheter was begun at the end of the procedure. The patient’s vital signs remained within 20% of baseline values throughout the operation.

After the 2-h incident-free procedure, the patient was taken to the postanesthesia care unit (PACU) awake and pain free. Her initial pain assessment in the PACU by verbal analog scale (VAS; 0 = no pain, 10 = worst pain imaginable) was zero. The patient was transferred to the 23-h recovery care center where the same local anesthetic infusion was continued. In addition, she was given oral acetaminophen 650 mg and IV ketorolac 30 mg every 6 h. Oral and IV opioid medications were available but not used by the patient.

The following morning, the patient was pain free and was discharged home with a continuous infusion of local anesthetic via a disposable infusion pump for an additional day. The patient’s catheter was connected to an AccufuserTM 275 10 mL/h (McKinley Medical, Wheat Ridge, CO) containing 275 mL of 0.2% ropivacaine. Detailed verbal and written (see Appendix) instructions about local anesthetic toxicity, pump function, and catheter removal were given. Telephone numbers to an anesthesiologist were also provided.

The patient was contacted the following day. She remained pain free and did not use any oral opioid. A family member had no difficulty with catheter removal, and the patient was satisfied with her anesthetic care.

Case 2
A 66-yr-old woman, ASA physical status II (95 kg; 165 cm) had undergone a left lumpectomy and a axillary dissection 1 mo earlier under regional anesthesia and T3 paravertebral catheter technique. The patient presented for bilateral simple mastectomies with tissue expanders. Her history included breast cancer, hypertension, chronic bronchitis, 30 pack-year smoking, and obesity. Her oral medication included hydrochlorothiazide 50 mg daily.

The patient requested paravertebral anesthesia with catheters for her mastectomies based on her previous positive experience with the technique. Bilateral T3 paravertebral catheters were placed using the technique and medications described in Case 1. To reduce total local anesthetic dose, 5 mL of 0.5% ropivacaine was used for the bilateral T1 and T6 blocks with an additional 30 mL injected at T3 bilaterally (15 mL each side). Management of this patient in the operating room was similar to Case 1.

One hour after the start of the operation, infusions of 0.2% ropivacaine at 6 mL/h were started via each catheter (12 mL/h total). Heart rate and blood pressure measurements remained within 20% of her initial values throughout the operation.

The patient was alert and comfortable in the PACU. During her overnight stay, both paravertebral catheters were infused. Her VAS remained <2 throughout the evening with the exception of a headache rated as an 8 that was treated with morphine 4 mg IV. The patient was comfortable the following morning. AccufuserTM 5 mL/h pumps were connected to each catheter and the patient was discharged with detailed instructions as previously described. The following morning, she complained of a VAS of 4 in her right breast that she treated with 4 tablets of oxycodone 5 mg with acetaminophen 325 mg during the night. Her left breast remained pain free. Interestingly, the patient noted that the right infusion pump did not appear to be infusing because no change in the fluid reservoir was observed compared with the left pump. The catheters were removed during the telephone interview. The patient’s spouse noted that the right catheter appeared to have become dislodged and kinked under the dressing. Despite this difficulty, the patient expressed satisfaction.


    Discussion
 Top
 Abstract
 Introduction
 Case 1
 Discussion
 Appendix A.
 References
 
These cases demonstrate a novel method of postoperative ambulatory pain control for breast surgery. Previous information describing continuous PVB with a disposable infusion pump at home is unavailable. The technique provided good operative anesthesia for major chest wall procedures as well as good postoperative analgesia. The patients required fewer postoperative opioids then we would expect after surgery of this magnitude and they were satisfied with their anesthetic care.

The use of paravertebral catheters in the management of thoracic pain after surgery or trauma has been well described (6–8). Percutaneous paravertebral catheters have traditionally been placed using the method described by Eason and Wyatt (9) using loss of resistance to air or saline with needle and syringe. In contrast, our system uses equipment that allows for loss of resistance technique whereas facilitating placement of the catheter with minimal needle manipulation. The system is also closed to atmospheric pressure, thus minimizing pneumothorax development should the needle violate the pleura. The initial use of a 25-gauge spinal needle to identify the depth of the transverse process before placement of the 18-gauge Tuohy needle may also reduce the risk of patient injury. Caudad needle redirection is preferred; accidental initial needle contact with a rib will result in contact with the transverse process at a more shallow depth instead of the pleura (10).

Pneumothorax after paravertebral catheter placement is a potential disadvantage of this technique (11); however, the incidence of pneumothorax after single-injection techniques is rare when the blocks are performed by experienced anesthesiologists (2,12). Catheter placement with a larger-gauge needle may increase this risk. An additional concern, particularly in outpatients, is spread of local anesthetic into the epidural space. This could result in bilateral blockade or hypotension. To address this concern, test doses were administered through the catheters, patients were observed overnight and evaluated before discharge, and we chose local anesthetic infusions that have previously been used safely in thoracotomy patients (13).

Local anesthetic toxicity is another concern with this technique. In our experience, adult patients tolerate the dosages described well. Unfortunately, data describing blood concentrations of ropivacaine at these dosages are unavailable.

Careful patient selection for home infusion techniques is essential for success. Patients must be able to understand pump function, recognize warning signs of toxicity, and have a dedicated home care provider to assist with catheter management and removal. Patient education with written and verbal instructions on home catheter management is essential. Finally, patients must be able to communicate questions or concerns to an anesthesiologist any time during the course of the home infusion.

These cases demonstrate an alternative method of paravertebral catheter insertion and outpatient analgesia delivery for breast surgery. Further investigation examining safety and feasibility compared with conventional treatments is warranted.


    Appendix A.
 Top
 Abstract
 Introduction
 Case 1
 Discussion
 Appendix A.
 References
 
Duke Ambulatory Surgery Center Written Instructions to Patients for Home Infusion Pumps


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    Acknowledgments
 
This work was supported by departmental funds.


    References
 Top
 Abstract
 Introduction
 Case 1
 Discussion
 Appendix A.
 References
 

  1. Klein SM, Bergh A, Steele SM, et al. Thoracic paravertebral block for breast surgery. Anesth Analg 2000; 90: 1402–5.[Abstract/Free Full Text]
  2. Karmakar MK. Thoracic paravertebral block. Anesthesiology 2001; 95: 771–80.[Web of Science][Medline]
  3. Ilfeld BM, Morey TE, Enneking FK. Continuous infraclavicular brachial plexus block for postoperative pain control at home: a randomized, double-blinded, placebo-controlled study. Anesthesiology 2002; 96: 1297–304.[Web of Science][Medline]
  4. Klein SM, Greengrass RA, Gleason DH, et al. Major ambulatory surgery with continuous regional anesthesia and a disposable infusion pump. Anesthesiology 1999; 91: 563–5.[Web of Science][Medline]
  5. Greengrass R, Steele S. Paravertebral blocks for breast surgery. Tech Reg Anesth Pain Manage 1998; 2: 8–12.
  6. Dhole S, Mehta Y, Saxena H, et al. Comparison of continuous thoracic epidural and paravertebral blocks for postoperative analgesia after minimally invasive direct coronary artery bypass surgery. J Cardiothorac Vasc Anesth 2001; 15: 288–92.[Web of Science][Medline]
  7. Karmakar MK, Chui PT, Joynt GM, Ho AM. Thoracic paravertebral block for management of pain associated with multiple fractured ribs in patients with concomitant lumbar spinal trauma. Reg Anesth Pain Med 2001; 26: 169–73.[Web of Science][Medline]
  8. Paniagua P, Catala E, Villar Landeira JM. Successful management of pleuritic pain with thoracic paravertebral block. Reg Anesth Pain Med 2000; 25: 651–3.[Web of Science][Medline]
  9. Eason MJ, Wyatt R. Paravertebral thoracic block: a reappraisal. Anaesthesia 1979; 34: 638–42.[Web of Science][Medline]
  10. Greengrass R, Buckenmaier CC III. Paravertebral anaesthesia/analgesia for ambulatory surgery. Best Pract Res Clin Anaesthesiol 2002; 16: 271–83.[Medline]
  11. Naja Z, Lonnqvist PA. Somatic paravertebral nerve blockade: incidence of failed block and complications. Anaesthesia 2001; 56: 1184–8.[Web of Science][Medline]
  12. Lonnqvist PA, MacKenzie J, Soni AK, Conacher ID. Paravertebral blockade: failure rate and complications. Anaesthesia 1995; 50: 813–5.[Web of Science][Medline]
  13. Matthews PJ, Govenden V. Comparison of continuous paravertebral and extradural infusions of bupivacaine for pain relief after thoracotomy. Br J Anaesth 1989; 62: 204–5.[Abstract/Free Full Text]
Accepted for publication April 23, 2003.




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This Article
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Right arrow Citing Articles via Web of Science (9)
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Right arrow Articles by Steele, S. M.
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Right arrow Articles by Buckenmaier, C. C., III
Right arrow Articles by Steele, S. M.
Related Collections
Right arrow Ambulatory
Right arrow Regional Anesthesia
Right arrow Pain


Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 2003 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press