ECONOMICS, EDUCATION, AND HEALTH SYSTEMS RESEARCH:

Neal H. Cohen

Anesthetic Depth Is Not (Yet) a Predictor of Mortality! (Editorial)
Anesth Analg 2005 100: 1-3. [Full Text] [PDF] [Request Permissions]  

Terri G. Monk, Vikas Saini, B. Craig Weldon, and Jeffrey C. Sigl

Anesthetic Management and One-Year Mortality After Noncardiac Surgery
Anesth Analg 2005 100: 4-10. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A prospective, longitudinal study of 1-yr postoperative mortality after noncardiac surgery confirms that comorbidity is the primary predictor and that intraoperative hypotension and prolonged cumulative deep hypnotic time are also significant risk factors. Intraoperative anesthetic management may have a greater effect on long-term outcomes than previously appreciated.

CARDIOVASCULAR ANESTHESIA:

Andrew I. Levin and Johan F. Coetzee

Arterial Oxygenation During One-Lung Anesthesia (Editorial)
Anesth Analg 2005 100: 12-14. [Full Text] [PDF] [Request Permissions]  

Laszlo L. Szegedi, Philippe Van der Linden, Anne Ducart, Pieter Cosaert, Jan Poelaert, Frank Vermassen, Eric P. Mortier, and Alain A. d’Hollander

The Effects of Acute Isovolemic Hemodilution on Oxygenation During One-Lung Ventilation
Anesth Analg 2005 100: 15-20. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This clinical study suggests that hemodilution impairs gas exchange during one-lung ventilation in patients with pulmonary hyperinflation and chronic obstructive lung disease, but not in patients with normal lungs; the reasons for this finding are not clear.

Mukesh Tripathi, Prakash K. Dubey, and Sushil P. Ambesh

Direction of the J-Tip of the Guidewire, in Seldinger Technique, Is a Significant Factor in Misplacement of Subclavian Vein Catheter: A Randomized, Controlled Study
Anesth Analg 2005 100: 21-24. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The direction of the guidewire J-tip plays a significant role in the malpositioning of catheters introduced via the right subclavian vein.

Susan B. McDonald, Eric Jacobsohn, Dan J. Kopacz, Seema Desphande, James D. Helman, Francis Salinas, and R. Alan Hall

Parasternal Block and Local Anesthetic Infiltration with Levobupivacaine After Cardiac Surgery with Desflurane: The Effect on Postoperative Pain, Pulmonary Function, and Tracheal Extubation Times
Anesth Analg 2005 100: 25-32. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Parasternal block combined with local anesthetic infiltration of the sternotomy wound and mediastinal tube sites after cardiac surgery can provide analgesia and reduce morphine requirements in the early postoperative period.

Yoshikazu Hamada, Yoshiyuki Kameyama, Hideyuki Narita, Kirk T. Benson, and Hiroshi Goto

Protamine After Heparin Produces Hypotension Resulting from Decreased Sympathetic Outflow Secondary to Increased Nitric Oxide in the Central Nervous System
Anesth Analg 2005 100: 33-37. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Using baroreceptor-denervated rabbits it was shown that decreased sympathetic outflow resulting from increased nitric oxide is one mechanism of protamine-induced hypotension.

Wai M. Ho, Nae C. Yang, K. C. Wong, and Kai L. Hwang

A Real-Time Method for Estimating the Concentrations of Isoflurane in Mixed Venous Blood by a Derived Fick’s Equation
Anesth Analg 2005 100: 38-45. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We established a new equation derived from Fick's laws to calculate the blood concentration of inhaled anesthetics in mixed venous blood (MVBC) without direct blood sampling. We found that the equation could be applied to estimate the real-time MVBC during cardiac surgery with isoflurane.

Matthias L. Riess, Leo G. Kevin, Joseph McCormick, Ming T. Jiang, Samhita S. Rhodes, and David F. Stowe

Anesthetic Preconditioning: The Role of Free Radicals in Sevoflurane-Induced Attenuation of Mitochondrial Electron Transport in Guinea Pig Isolated Hearts
Anesth Analg 2005 100: 46-53. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Nitric oxide and other reactive oxygen species mediate sevoflurane-induced attenuation of mitochondrial electron transport in Langendorff-prepared hearts. This may lead to a positive feedback mechanism that initiates cardiac anesthetic preconditioning and attenuates ischemia/reperfusion injury.

Thorsten Haas, Petra Innerhofer, Gabriele Kühbacher, and Dietmar Fries

Successful Reversal of Deleterious Coagulopathy by Recombinant Factor VIIa (Case Report)
Anesth Analg 2005 100: 54-58. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Recombinant activated factor VIIa (rFVIIa) proved to be a powerful therapeutic option for the management of life threatening bleeding caused by unresponsive coagulopathy. Roughly estimated, rFVIIa is as expensive as accepted conventional therapy but is also impressively effective in reversing persistent coagulopathy, even when traditional transfusion therapy fails.

PEDIATRIC ANESTHESIA:

Alan R. Tait and Shobha Malviya

Anesthesia for the Child with an Upper Respiratory Tract Infection: Still a Dilemma? (Review Article)
Anesth Analg 2005 100: 59-65. [Abstract] [Full Text] [PDF] [Request Permissions]  

Hannu Kokki, Paula Ylönen, Merja Laisalmi, Marja Heikkinen, and Matti Reinikainen

Isobaric Ropivacaine 5 mg/mL for Spinal Anesthesia in Children
Anesth Analg 2005 100: 66-70. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study showed that spinal ropivacaine at a dose of 0.5 mg/kg (maximum dose 20 mg) is an appropriate anesthetic for children aged 1-17 yr for surgery below the umbilicus with duration of <90 min.

Simon D. Whyte, Peter D. Booker, and David G. Buckley

The Effects of Propofol and Sevoflurane on the QT Interval and Transmural Dispersion of Repolarization in Children
Anesth Analg 2005 100: 71-77. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study indicates that although propofol and sevoflurane both prolong the corrected QT interval in healthy children, neither anesthetic increases transmural dispersion of repolarization, implying a small risk of inducing torsades de pointes.

Helge Schoenfeld, Manfred Muhm, Ulrich R. Doepfmer, Wolfgang J. Kox, Claudia Spies, and Hartmut Radtke

The Functional Integrity of Platelets in Volume-Reduced Platelet Concentrates
Anesth Analg 2005 100: 78-81. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Volume reduction of platelet concentrates may be indicated for thrombocytopenic pediatric patients with a risk of excessive intravascular volume. We studied the spontaneous, adenosine diphosphate-induced, and collagen-induced activation of platelets before and after volume reduction of single-donor-apheresis platelet concentrates. The procedure resulted in slightly impaired in vitro platelet function.

Tuta Ion, Scott D. Cook-Sather, Richard S. Finkel, and Giovanni Cucchiaro

Fascia Iliaca Block for an Infant with Arthrogryposis Multiplex Congenita Undergoing Muscle Biopsy (Case Report)
Anesth Analg 2005 100: 82-84. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This is a case report describing the successful use of regional anesthesia in a child with multiple deformities, in whom general anesthesia may have resulted in severe complications.

Anil Agarwal, Mehdi Raza, Sanjay Dhiraaj, Rajan Saxena, Prabhat K. Singh, and Ravindra Pandey

Is Ketamine a Safe Anesthetic for Percutaneous Liver Biopsy in a Liver Transplant Recipient Immunosuppressed with Cyclosporine? (Case Report)
Anesth Analg 2005 100: 85-86. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Liver transplant recipient patients, despite immunosuppression, may require liver biopsy to exclude graft rejection. We report convulsions after IV ketamine in a liver transplant recipient immunosuppressed by cyclosporine. We suggest caution with ketamine anesthesia in a patient immunosuppressed with cyclosporine.

AMBULATORY ANESTHESIA:

Anna Lee, Tony Gin, Angel S. C. Lau, and Floria F. Ng

A Comparison of Patients’ and Health Care Professionals’ Preferences for Symptoms During Immediate Postoperative Recovery and the Management of Postoperative Nausea and Vomiting
Anesth Analg 2005 100: 87-93. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Patients' and health care professionals' preferences for recovery and antiemetic treatment were compared. There were small differences between groups in the importance of pain, sedation, efficacy of the antiemetic, and extra cost. There was no preference in either group for a policy of effective treatment versus routine prophylaxis.

Leonardo Rizzo, Maurizio Marini, Chiara Rosati, Italo Calamai, Michela Nesi, Roberto Salvini, Cinzia Mazzini, Fiamma Campana, and Enzo Brizzi

Peribulbar Anesthesia: A Percutaneous Single Injection Technique with a Small Volume of Anesthetic
Anesth Analg 2005 100: 94-96. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Potential complications associated with regional anesthesia in ophthalmic surgery led to the proposal of a single, rather than multiple, injection technique of regional anesthesia. The described percutaneous peribulbar medial single injection technique with very small volume of anesthetic is a simple and satisfactory alternative to the classical techniques.

ANESTHETIC PHARMACOLOGY:

Bruno H. Pypendop and Jan E. Ilkiw

The Effects of Intravenous Lidocaine Administration on the Minimum Alveolar Concentration of Isoflurane in Cats
Anesth Analg 2005 100: 97-101. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: IV lidocaine decreased the minimum alveolar concentration of isoflurane in a linear and dose-dependent fashion in cats. These results suggest that IV lidocaine might be useful whenever decreasing the requirements for inhaled anesthetics is desirable.

Andrea Paris, Christina Ohlendorf, Michael Marquardt, Berthold Bein, James M. Sonner, Jens Scholz, and Peter H. Tonner

The Effect of Meperidine on Thermoregulation in Mice: Involvement of ₂-Adrenoceptors
Anesth Analg 2005 100: 102-106. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Meperidine decreases the threshold for nonshivering thermogenesis in mice. This effect was abolished by administration of the {alpha}2-adrenoceptor antagonist atipamezole, suggesting a predominant role of {alpha}2-adrenoceptors in the inhibition of thermoregulation by meperidine. This model of thermoregulation in mice may be useful to further elucidate general mechanisms of thermoregulation.

Hiroko Iwakiri, Noboru Nishihara, Osamu Nagata, Takashi Matsukawa, Makoto Ozaki, and Daniel I. Sessler

Individual Effect-Site Concentrations of Propofol Are Similar at Loss of Consciousness and at Awakening
Anesth Analg 2005 100: 107-110. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Propofol can be titrated to the concentration that produces consciousness in individual patients. Provided that the propofol effect-site concentration does not much exceed the concentration initially required to produce unconsciousness, patients can be expected to awaken quickly on completion of the procedure.

Stavros G. Memtsoudis, Andrew H. S. The, and Paul M. Heerdt

Autonomic Mechanisms in the Age-Related Hypotensive Effect of Propofol
Anesth Analg 2005 100: 111-115. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Clinical experience suggests that aged individuals exhibit larger hypotensive effects after induction doses of propofol compared with young adults. The mechanism behind this observation remains largely unstudied. Our data gathered in a rabbit model suggest that age-related reduction in sensitivity of autonomic reflexes may contribute substantially to the increased hypotensive effect of propofol in the aged.

Keiichi Nitahara, Shinjiro Shono, Takamitsu Hamada, Hideyuki Higuchi, Tadakazu Sakuragi, and Kazuo Higa

The Effect of Adenosine Triphosphate on Vecuronium-Induced Neuromuscular Block
Anesth Analg 2005 100: 116-119. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In contrast to animal studies, this randomized-controlled study in humans demonstrated that adenosine triphosphate (ATP) 0.1 mg {middle dot} kg-1 {middle dot} min-1 did not enhance the neuromuscular block induced by vecuronium and, indeed, contributed to an increased incidence of hypotension. These findings suggest possible advantages and limitations of intraoperative use of ATP.

Michael K. Herbert, Rebecca Weis, Peter Holzer, and Norbert Roewer

Peristalsis in the Guinea Pig Small Intestine In Vitro Is Impaired by Acetaminophen but Not Aspirin and Dipyrone
Anesth Analg 2005 100: 120-127. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Acetaminophen (paracetamol) concentration-dependently impairs peristalsis in the guinea pig small intestine in vitro. The inhibitory action is mediated through activation of endogenous opioidergic pathways, small conductance Ca2+-activated potassium channels, and, presumably, cyclooxygenase -3. Acetylsalicylic acid (aspirin) and dipyrone (metamizol) have no inhibitory effect.

Caroline Stabernack, Yi Zhang, James M. Sonner, Michael Laster, and Edmond I Eger, II

Thiopental Produces Immobility Primarily by Supraspinal Actions in Rats
Anesth Analg 2005 100: 128-136. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Thiopental produces immobility in response to noxious stimuli predominantly by actions on supraspinal sites.

Marilyn Gosgnach, Guy Aymard, Catherine Huraux, Marie Hélène Fléron, Pierre Coriat, and Bertrand Diquet

Atenolol Administration via a Nasogastric Tube After Abdominal Surgery: An Unreliable Route (Brief Report)
Anesth Analg 2005 100: 137-140. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Atenolol administered at the same preoperative dose via a nasogastric tube after abdominal surgery leads to reduced bioavailability due to decreased absorption. The beneficial effects of perioperative IV atenolol cannot be expected from this route of administration.

TECHNOLOGY, COMPUTING, AND SIMULATION:

Cynthia A. Wong, Robert J. Fragen, Paul C. Fitzgerald, and Robert J. McCarthy

The Association Between Propofol-Induced Loss of Consciousness and the SNAP^TM Index
Anesth Analg 2005 100: 141-148. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The SNAPTM is a processed electroencephalogram monitor that uses an algorithm based on low- and high-frequency spectral components to derive the SNAPTM index. The SNAPTM index correlated with propofol-induced loss of consciousness.

Marie-Eve Nepveu, François Donati, and Louis-Philippe Fortier

Train-of-Four Stimulation for Adductor Pollicis Neuromuscular Monitoring Can Be Applied at the Wrist or Over the Hand
Anesth Analg 2005 100: 149-154. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Adductor pollicis monitoring is usually performed by applying electrodes over the ulnar nerve at the wrist. An alternative is to stimulate over the muscle itself in the hand. Train-of-four ratios at the hand and the wrist are comparable, and direct muscle stimulation does not occur.

Ngo K. Nguyen, Fima Lenkovsky, and Girish P. Joshi

Patient State Index During a Cardiac Arrest in the Operating Room (Case Report)
Anesth Analg 2005 100: 155-157. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A 53-yr-old man undergoing laparoscopic cholecystectomy experienced cardiac arrest intraoperatively. Patient state index values decreased to single digits during the cardiac arrest and returned to baseline after successful cardiopulmonary resuscitation.

Yasuhiro Morimoto, Yoko Monden, Kazunobu Ohtake, Takefumi Sakabe, and Satoshi Hagihira

The Detection of Cerebral Hypoperfusion with Bispectral Index Monitoring During General Anesthesia (Case Report)
Anesth Analg 2005 100: 158-161. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We describe a patient in whom bispectral index decreased to 0 during general anesthesia, possibly because of cerebral hypoperfusion.

PAIN MEDICINE:

Peter E. Frasco, Juraj Sprung, and Terrence L. Trentman

The Impact of the Joint Commission for Accreditation of Healthcare Organizations Pain Initiative on Perioperative Opiate Consumption and Recovery Room Length of Stay
Anesth Analg 2005 100: 162-168. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Despite evidence regarding the benefits of effective pain treatment, continued disparities in practice have led the Joint Commission for Accreditation of Health Care Organizations to mandate standards to assure that all patients with pain are identified and appropriately treated. Our study disclosed that, after introduction of new pain standards, postanesthetic care unit use of opiate analgesics increased without significant adverse effects.

Barbara Kapfer, Pascal Alfonsi, Bruno Guignard, Daniel I. Sessler, and Marcel Chauvin

Nefopam and Ketamine Comparably Enhance Postoperative Analgesia
Anesth Analg 2005 100: 169-174. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Ketamine 10 mg and nefopam 20 mg comparably potentiate opioid analgesia; each reduces opioid requirements by approximately 40%. Ketamine administration was associated with sedation, whereas nefopam produced tachycardia and sweating. However, none of the side effects was serious. Either drug can thus be used to potentiate opioid analgesia.

Shin Onizuka, Toshiharu Kasaba, Toshiro Hamakawa, and Mayumi Takasaki

Lidocaine Excites Both Pre- and Postsynaptic Neurons of Reconstructed Respiratory Pattern Generator in Lymnaea stagnalis
Anesth Analg 2005 100: 175-182. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Lidocaine reduces inhibitory synaptic transmission. However, lidocaine induces a decrease in the outward voltage-gated potassium current, which leads to depolarization and general excitation of both presynaptic and postsynaptic neurons. Lidocaine's side effects, such as convulsion, seizure, and hyperventilation, may result from such changes in general neuronal excitability.

SPECIAL ARTICLES:

Perry G. Fine

The Evolving and Important Role of Anesthesiology in Palliative Care
Anesth Analg 2005 100: 183-188. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Safe and comfortable dying at the end of a progressive, life-limiting illness are key outcome measures in end-of-life care and are high priorities voiced by patients and their families. Anesthesiologists have unique skills that could greatly improve these critically important outcomes.

CRITICAL CARE AND TRAUMA:

Stephan M. Jakob

Blindness in the Intensive Care Unit (Editorial)
Anesth Analg 2005 100: 189-191. [Full Text] [PDF] [Request Permissions]  

Lorri A. Lee, Avery B. Nathens, Bryan S. Sires, Megan K. McMurray, and Arthur M. Lam

Blindness in the Intensive Care Unit: Possible Role for Vasopressors? (Case Report)
Anesth Analg 2005 100: 192-195. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Four cases of blindness in critically ill patients are described, three of which occurred outside the operative arena. Venous congestion and hypotension are among the potential risk factors for the development of ischemic optic neuropathy. The role of vasopressors remains speculative but should be considered during treatment of critically ill patients.

REVIEW ARTICLES:

Michael G. Mythen

Postoperative Gastrointestinal Tract Dysfunction
Anesth Analg 2005 100: 196-204. [Abstract] [Full Text] [PDF] [Request Permissions]  

Maria Akrofi, Scott Miller, Steve Colfar, Peter R. Corry, Brian M. Fabri, Mark D. Pullan, Glenn N. Russell, and Mark A. Fox

A Randomized Comparison of Three Methods of Analgesia for Chest Drain Removal in Postcardiac Surgical Patients
Anesth Analg 2005 100: 205-209. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The efficacy of IV morphine, subcutaneous bupivacaine, and inhaled 50% nitrous oxide in oxygen as analgesia for the removal of mediastinal chest drains after cardiac surgery was compared. All methods afford hemodynamic stability, but Entonox was the least effective in providing analgesia.

Martin Beiderlinden, Michael Adamzik, and Jürgen Peters

Conservative Treatment of Tracheal Injuries
Anesth Analg 2005 100: 210-214. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Bronchoscopic-guided bridging of tracheal tears with an artificial airway is a rapid and easy method to stop immediately life-threatening air leakage. Furthermore, with conservative treatment, tracheal injuries can heal without infectious or stenotic complications. Therefore, conservative treatment should be considered an alternative to surgery in selected patients.

NEUROSURGICAL ANESTHESIA:

John R. Feiner, Philip E. Bickler, Sergio Estrada, Paul H. Donohoe, Christian S. Fahlman, and Jennifer A. Schuyler

Mild Hypothermia, but Not Propofol, Is Neuroprotective in Organotypic Hippocampal Cultures
Anesth Analg 2005 100: 215-225. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The neuroprotective qualities of propofol are controversial. In rat hippocampal slice cultures, mild hypothermia (35{degrees}C), but not propofol, was protective after oxygen and glucose deprivation. Failure of propofol neuroprotection in this model may be related to relatively modest inhibition of glutamate receptor responses and excitotoxicity.

Claudia Stapelfeldt, Errol P. Lobo, Ronald Brown, and Pekka O. Talke

Intraoperative Clonidine Administration to Neurosurgical Patients
Anesth Analg 2005 100: 226-232. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We determined the dose of clonidine to prevent postoperative shivering in neurosurgical patients whose core temperature was 35{degrees}C at the end of surgery and that clonidine administered to neurosurgical patients did not delay emergence from anesthesia. Our results imply that clonidine may be used in neurosurgical patients to prevent postoperative shivering.

OBSTETRIC ANESTHESIA:

Shmuel Evron, Marek Glezerman, Oskar Sadan, Mona Boaz, and Tiberiu Ezri

Remifentanil: A Novel Systemic Analgesic for Labor Pain
Anesth Analg 2005 100: 233-238. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Patient-controlled IV remifentanil administered intermittently in incremental small doses was effective and had few side effects to the parturient and the fetus. This option should be considered when an alternative to neuraxial anesthesia is necessary.

Ashraf S. Habib, Holly A. Muir, William D. White, Tede E. Spahn, Adeyemi J. Olufolabi, Terrance W. Breen, and The Duke Women’s Anesthesia Research Group

Intrathecal Morphine for Analgesia After Postpartum Bilateral Tubal Ligation
Anesth Analg 2005 100: 239-243. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The addition of 50 {micro}g of morphine to intrathecal hyperbaric bupivacaine and fentanyl provided improved postoperative analgesia, less need for rescue analgesics, and a greater degree of patient satisfaction compared with a similar technique without morphine in women undergoing postpartum bilateral tubal ligation under spinal anesthesia.

REGIONAL ANESTHESIA:

S. C. O’Riain, D. J. Buggy, M. J. Kerin, R. W. G. Watson, and D. C. Moriarty

Inhibition of the Stress Response to Breast Cancer Surgery by Regional Anesthesia and Analgesia Does Not Affect Vascular Endothelial Growth Factor and Prostaglandin E₂
Anesth Analg 2005 100: 244-249. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In a prospective, randomized, double-blind study, inhibition of the surgical stress response by paravertebral regional anesthesia and analgesia had no effect on serum levels of putative breast cancer angiogenic factors, vascular endothelial growth factor and prostaglandin E2, compared with general anesthesia and postoperative opioid analgesia.

Manuel Taboada, Peter G. Atanassoff, Jaime Rodríguez, Joaquín Cortés, Sabela Del Rio, Juan Lagunilla, Francisco Gude, and Julián Álvarez

Plantar Flexion Seems More Reliable than Dorsiflexion with Labat’s Sciatic Nerve Block: A Prospective, Randomized Comparison
Anesth Analg 2005 100: 250-254. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Plantar flexion of the foot during Labat's classic posterior sciatic nerve block predicts a shorter onset time and more frequent success rate than dorsiflexion.

Hendrik Freise, Sören Anthonsen, Lars G. Fischer, Hugo K. Van Aken, and Andreas W. Sielenkämper

Continuous Thoracic Epidural Anesthesia Induces Segmental Sympathetic Block in the Awake Rat
Anesth Analg 2005 100: 255-262. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Continuous thoracic epidural anesthesia (TEA) was applied in awake rats. Sympathetic block was evaluated by changes in skin temperature. TEA induced segmental sympathetic block without cardiorespiratory side effects. This new technique may be applicable in research evaluating TEA in prolonged models of critical illness.

Vincent Minville, Luc N'Guyen, Clement Chassery, Paul Zetlaoui, Jean-Claude Pourrut, Claude Gris, Bernard Eychennes, Dan Benhamou, and Kamran Samii

A Modified Coracoid Approach to Infraclavicular Brachial Plexus Blocks Using a Double-Stimulation Technique in 300 Patients (Brief Report)
Anesth Analg 2005 100: 263-265. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In this study, a modified coracoid approach to the infraclavicular brachial plexus performed using a double-stimulation technique is described and its efficacy assessed. This modified approach had frequent success and was safe in this cohort.

Satoki Inoue, Naoko Nishimine, and Hitoshi Furuya

Unintentional Intrapleural Insertion of an Epidural Catheter: Should We Remove It or Leave It In Situ to Provide Perioperative Analgesia? (Case Report)
Anesth Analg 2005 100: 266-268. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In cases in which an intended thoracic epidural catheter is found to be in the intrapleural cavity at the time of surgery, the administration of local anesthetic through the intrapleural catheter could be a potential alterative postoperative analgesic method.

GENERAL ARTICLES:

John H. Eisenach, Tasha L. Pike, Diane E. Wick, Niki M. Dietz, Robert D. Fealey, John L. D. Atkinson, and Nisha Charkoudian

A Comparison of Peripheral Skin Blood Flow and Temperature During Endoscopic Thoracic Sympathotomy
Anesth Analg 2005 100: 269-276. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Termed sympathotomy, endoscopic surgical disconnection of the sympathetic chain to the upper extremities is an effective therapy for people affected with excessive sweating of the hands. Success relies on intraoperative monitoring of denervation, which can be determined rapidly by monitoring skin blood flow with laser Doppler flowmetry.

Craig G. Crandall, Dan M. Meyer, Scott L. Davis, and Suzanne M. Dellaria

Palmar Skin Blood Flow and Temperature Responses Throughout Endoscopic Sympathectomy
Anesth Analg 2005 100: 277-283. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Thoracic surgical sympathectomy is a common procedure to treat hyperhidrosis. This study revealed that palmar skin blood flow increased during cautery of the parietal pleura before the disruption of the ganglion. This observation may limit the utility skin blood-flow responses for confirming a successful sympathectomy.

Pankaj Kundra, N. Sujata, and M. Ravishankar

Conventional Tracheal Tubes for Intubation Through the Intubating Laryngeal Mask Airway
Anesth Analg 2005 100: 284-288. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The laryngeal mask airway (LMA)-FastrachTM silicone wire-reinforced tracheal tube (FTST) was designed for tracheal intubation through the intubating LMA (ILMA). This study demonstrates that a prewarmed Rusch polyvinyl chloride tube can be used as successfully as an FTST for blind tracheal intubation through the ILMA, whereas the Rusch latex armored tube is associated with more frequent failure and esophageal intubation.

LETTERS TO THE EDITOR:

Robert Hanss, Dietmar Block, Peter H. Tonner, Berthold Bein, Timo Laitio, Tom Kuusela, Heikki Huikuri, Jouko Jalonen, Erkki Kentala, Timo Mäkikallio, Hans Helenius, Olar Pullisaar, Jaakko Hartiala, and Harry Scheinin

Prediction of Postoperative Myocardial Ischemia by Fractal Heart Rate Dynamics • Response
Anesth Analg 2005 100: 289-290. [Full Text] [PDF] [Request Permissions]  

Tim M. Cook, Jerry P. Nolan, J. Brimacombe, and C. Keller

Failed Obstetric Tracheal Intubation and Postoperative Respiratory Support with the Proseal Laryngeal Mask Airway • Response
Anesth Analg 2005 100: 290-291. [Full Text] [PDF] [Request Permissions]  

Govind R. Rajan

Tracheal Perforation with Modified Broncho-Cath®: Is It the Tube or the Technique?
Anesth Analg 2005 100: 291. [Full Text] [PDF] [Request Permissions]  

M. Sean Kincaid, Colleen M. Douville, Arthur M. Lam, Rao N. Gundamraj, and Kathryn K. Lauer

Perioperative Use of Transcranial Doppler • Response
Anesth Analg 2005 100: 291-292. [Full Text] [PDF] [Request Permissions]  

Peter Rosenberger, Stanton K. Shernan, Thomas Weissmüller, Holger K. Eltzschig, Chen-Wei Lu, Yi-Sharng Chen, and Ming-Jiuh Wang

Role of Intraoperative Transesophageal Echocardiography for Diagnosing and Managing Pulmonary Embolism in the Perioperative Period • Response
Anesth Analg 2005 100: 292-293. [Full Text] [PDF] [Request Permissions]  

Tomasz Gaszynski

BIS in Brain Injury
Anesth Analg 2005 100: 293-294. [Full Text] [PDF] [Request Permissions]  

Indu Sen, K. L. Narsimhan, and P. Chari

Multiple Tracheobronchial Foreign Bodies in an Infant
Anesth Analg 2005 100: 294. [Full Text] [PDF] [Request Permissions]  

Yuko Yoshida, Takashi Hongo, Atsuhiro Sakamoto, and Ryo Ogawa

Successful Management of Tachycardiac Atrial Fibrillation in a Septic Patient with Landiolol
Anesth Analg 2005 100: 294. [Full Text] [PDF] [Request Permissions]  

Karim Bendjelid, Kathryn E. Glas, and Jack S. Shanewise

ECG Monitoring Is Essential for Echocardiographic Analysis • Response
Anesth Analg 2005 100: 294-296. [Full Text] [PDF] [Request Permissions]  

Baljit Singh, Chhavi Papneja, Vishnu Datt, Ban C. H. Tsui, and Stephen Malherbe

Reversal of an Unintentional Spinal Anesthetic by Cerebrospinal Lavage • Response
Anesth Analg 2005 100: 296-297. [Full Text] [PDF] [Request Permissions]  

Andrea Michalek-Sauberer, Hermann Gilly, Thomas M. Hemmerling, Guillaume Michaud, Stéphane Deschamps, and Guillaume Trager

Neuromuscular Blockade at Laryngeal Muscles • Response
Anesth Analg 2005 100: 297-298. [Full Text] [PDF] [Request Permissions]  

J. Brimacombe and C. Keller

A Proposed Algorithm for the Management of Airway Obstruction with the Proseal^TM Laryngeal Mask Airway
Anesth Analg 2005 100: 298-299. [Full Text] [PDF] [Request Permissions]  

Rudolph H. de Jong and Zafer Salim Tabboush

"Tumescent Anesthesia" for Office-Based Liposuction • Response
Anesth Analg 2005 100: 299-300. [Full Text] [PDF] [Request Permissions]  

Thomas J. Papadimos and Anthony L. Braida

Potential Surgical Site Misidentification
Anesth Analg 2005 100: 300. [Full Text] [PDF] [Request Permissions]  

Altaf Hussain

Cervical Spine Firearm Injury: Bullets Do Not Have Eyes
Anesth Analg 2005 100: 300-301. [Full Text] [PDF] [Request Permissions]  

BOOK AND MULTIMEDIA REVIEWS:

Marcel E. Durieux and Mary K. McHugh

Pain Research: Methods and Protocols. • Obstetric Anesthesia: Principles and Practice, 3rd ed. • Books and Multimedia Received
Anesth Analg 2005 100: 302-303. [Full Text] [PDF] [Request Permissions]  

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