CARDIOVASCULAR ANESTHESIA:

Jan Frässdorf, Nina C. Weber, Detlef Obal, Octavian Toma, Jost Müllenheim, Georg Kojda, Benedikt Preckel, and Wolfgang Schlack

Morphine Induces Late Cardioprotection in Rat Hearts In Vivo: The Involvement of Opioid Receptors and Nuclear Transcription Factor B
Anesth Analg 2005 101: 934-941. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Like lipopolysaccharide, morphine induces late preconditioning and activation of nuclear transcription factor-{kappa}B. Opioid receptors are involved as mediators in both morphine- and lipopolysaccharide-induced late preconditioning but as triggers only in morphine-induced late preconditioning.

Dorothee Weihrauch, John G. Krolikowski, Martin Bienengraeber, Judy R. Kersten, David C. Warltier, and Paul S. Pagel

Morphine Enhances Isoflurane-Induced Postconditioning Against Myocardial Infarction: The Role of Phosphatidylinositol-3-Kinase and Opioid Receptors in Rabbits
Anesth Analg 2005 101: 942-949. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The results of this study indicate that morphine enhances isoflurane-induced postconditioning by activating phosphatidylinositol-3-kinase and opioid receptors in vivo. A reduction in apoptotic cell death contributes to preservation of myocardial integrity during postconditioning by isoflurane and morphine.

Masanori Onomoto, Isao Tsuneyoshi, Arata Yonetani, Shoich Suehiro, Kazuhisa Matsumoto, Ryuzo Sakata, and Yuichi Kanmura

Differential Pharmacologic Sensitivities of Phosphodiesterase-3 Inhibitors Among Human Isolated Gastroepiploic, Internal Mammary, and Radial Arteries
Anesth Analg 2005 101: 950-956. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Because three phosphodiesterase-3 inhibitors (milrinone, olprinone, and amrinone) differed in their vasodilator potencies (against the contractile response to either norepinephrine or a thromboxane A2 analog) among human arteries removed from different parts of the body, their vascular relaxation profiles should be considered before they are used clinically.

Thomas Schilling, Alf Kozian, Christof Huth, Frank Bühling, Moritz Kretzschmar, Tobias Welte, and Thomas Hachenberg

The Pulmonary Immune Effects of Mechanical Ventilation in Patients Undergoing Thoracic Surgery
Anesth Analg 2005 101: 957-965. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Reductions of tidal volume, with subsequently decreased peak airway pressures, may reduce some alveolar inflammatory responses seen with mechanical ventilation.

Bon N. Koo, Hae K. Kil, Jin-S Choi, Ji Y. Kim, Duk H. Chun, and Yong W. Hong

Hepatic Resection by the Cavitron Ultrasonic Surgical Aspirator® Increases the Incidence and Severity of Venous Air Embolism
Anesth Analg 2005 101: 966-970. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study demonstrated that venous air embolism during hepatic resection was more frequent and severe when using the Cavitron Ultrasonic Surgical Aspirator(R). Although we found no evidence of hemodynamic compromise, increased venous air embolism may increase the risk of paradoxical embolism in patients with liver cirrhosis.

J. Thomas Murphy and Brenda G. Fahy

Thrombosis of Sirolimus-Eluting Coronary Stent in the Postanesthesia Care Unit (Case Report)
Anesth Analg 2005 101: 971-973. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A coronary stent thrombosed postoperatively requiring cardiac catheterization.

PEDIATRIC ANESTHESIA:

Kim Jin-Hee, Young-Jin Ro, Min Seong-Won, Kim Chong-Soo, Kim Seong-Deok, Jun Ho Lee, and Bahk Jae-Hyon

Elongation of the Trachea During Neck Extension in Children: Implications of the Safety of Endotracheal Tubes
Anesth Analg 2005 101: 974-977. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The distance between endotracheal tube tip and vocal cords is directly related to the risk of extubation. Despite tracheal elongation, neck extension actually displaced the endotracheal tube tip to the vocal cords in older children.

Mary E. McCann, David Hill, Kristin C. Thomas, David Zurakowski, and Peter C. Laussen

A Comparison of Radial Artery Blood Pressure Determination Between the Vasotrac Device and Invasive Arterial Blood Pressure Monitoring in Adolescents Undergoing Scoliosis Surgery
Anesth Analg 2005 101: 978-985. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The Vasotrac, a noninvasive arterial blood pressure monitor, performs well in the prone position in adolescent patients undergoing scoliosis surgery using a technique of mild-to-moderate induced hypotension.

Erinn T. Rhodes, Lynne R. Ferrari, and Joseph I. Wolfsdorf

Perioperative Management of Pediatric Surgical Patients with Diabetes Mellitus (Medical Intelligence)
Anesth Analg 2005 101: 986-999. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The evolution of diabetes care for children has made the management of perioperative blood glucose levels a greater challenge for pediatric anesthesiologists. A standardized algorithm for the perioperative management of pediatric patients with type 1 or type 2 diabetes mellitus is presented.

Edward R. Mariano, Larry F. Chu, Craig T. Albanese, and Chandra Ramamoorthy

Successful Thoracoscopic Repair of Esophageal Atresia with Tracheoesophageal Fistula in a Newborn with Single Ventricle Physiology (Case Report)
Anesth Analg 2005 101: 1000-1002. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Esophageal atresia and tracheoesophageal fistula in conjunction with single ventricle physiology carries a significant risk of mortality. We present the anesthetic management of a neonate with unpalliated tricuspid atresia who underwent a thoracoscopic tracheoesophageal fistula repair.

Douglas G. Ririe, Patrick E. Lantz, Steven S. Glazier, and Louis C. Argenta

Transfusion-Related Acute Lung Injury in an Infant During Craniofacial Surgery (Case Report)
Anesth Analg 2005 101: 1003-1006. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Transfusion-related acute lung injury (TRALI) is a life-threatening problem that can occur during blood product transfusion in patients of any age. Understanding the pathophysiology may help make an earlier diagnosis to reduce more serious adverse outcomes.

AMBULATORY ANESTHESIA:

Veysel Erden, Zehra Yangin, Kerem Erkalp, Hamdi Delatioglu, Feyza Bahçeci, and Ayse Seyhan

Increased Progesterone Production During the Luteal Phase of Menstruation May Decrease Anesthetic Requirement
Anesth Analg 2005 101: 1007-1011. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The aim of this study was to determine the effect of high progesterone levels on anesthetic requirement. We measured progesterone levels before surgery and calculated the sevoflurane dose (MAC-h) required to maintain a constant bispectral index value. The dose of sevoflurane correlated inversely with serum progesterone concentrations.

Niall Patton, Tahira Y. Malik, and Tariq M. Aslam

Sub-Tenon’s Anesthetic Administration for Cataract Surgery: How Much Stays In?
Anesth Analg 2005 101: 1012-1014. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The volume of anesthetic solution remaining within sub-Tenon's space correlates with motor block. The amount of volume lost as a percentage of total administered is independent of the volume injected, suggesting sub-Tenon's space is not limited to a finite injected volume less than 5 mL and may be capable of receiving larger volumes of anesthetic to improve motor block.

ANESTHETIC PHARMACOLOGY:

Tetsuya Kakutani, Koji Ogawa, Shizue Iwahashi, Kazuhiro Mizumoto, and Yoshio Hatano

Sevoflurane Enhances Nitroglycerin Tolerance in Rat Aorta: Implications for the Desensitization of Soluble Guanylate Cyclase Possibly Through the Additive Generation of Superoxide Anions and/or Hydroxyl Radicals Within Vascular Smooth Muscle
Anesth Analg 2005 101: 1015-1022. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The effects of sevoflurane and isoflurane on the development of nitroglycerin (TNG) tolerance were investigated in isolated rat aorta. TNG tolerance was induced by incubation of the vascular tissue in the bathing media containing TNG (10-5 M) for 30 min. Sevoflurane, but not isoflurane, enhances TNG tolerance, possibly by additive generation of oxygen-derived free radicals.

R. Ross Kennedy

The Effect of Using Different Values for the Effect-Site Equilibrium Half-Time on the Prediction of Effect-Site Sevoflurane Concentration: A Simulation Study
Anesth Analg 2005 101: 1023-1028. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A model-based predictive display to guide effect site targeting of volatile anesthesia is described. The effect of using different values for the rate of transfer of sevoflurane between central and effect site compartments is explored. The results suggest effect site concentration is relatively insensitive to 50-100% variations in half-time for plasma effect-site equilibrium.

Eric P. Wilkens and Bill J. Yates

Pretreatment with Ondansetron Blunts Plasma Vasopressin Increases Associated with Morphine Administration in Ferrets
Anesth Analg 2005 101: 1029-1033. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The antiemetic, ondansetron, has an effect not only on clinically perceived vomiting, but also on plasma vasopressin level.

Yon Hee Shim, Cheung Soo Shin, Chul Ho Chang, and Yang-Sik Shin

Optimal End-Tidal Sevoflurane Concentration for the Removal of the Laryngeal Mask Airway in Anesthetized Adults
Anesth Analg 2005 101: 1034-1037. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Because the removal of the laryngeal mask airway (LMA) in the anesthetized state is required in some clinical situations, we sought to determine the end-tidal concentration of sevoflurane to safely remove the LMA in anesthetized adults.

Kazuyoshi Hirota, Mihoko Kudo, Hiroshi Hashimoto, and Tetsuya Kushikata

The Efficacy of Preanesthetic Proton Pump Inhibitor Treatment for Patients on Long-Term H₂ Antagonist Therapy
Anesth Analg 2005 101: 1038-1041. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We previously reported that more than 4 wk of administration of H2-antagonists may produce a full tolerance to preanesthetic H2-antagonists. The present study suggests that a proton pump inhibitor may be effective for prophylaxis of acid aspiration pneumonia in patients showing the full tolerance to H2 antagonists.

Bharat Keshavaprasad, Canhui Liu, John D. Au, Christoph H. Kindler, Joseph F. Cotten, and C. Spencer Yost

Species-Specific Differences in Response to Anesthetics and Other Modulators by the K_2P Channel TRESK
Anesth Analg 2005 101: 1042-1049. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Mouse and rat TRESK (TWIK-related spinal cord K+ channel) have different pharmacologic responses compared with human TRESK. In particular, we found stereospecific differences in response to isoflurane by the rodent TRESKs but not by human TRESK. TRESK may be a target site for the mechanism of action of volatile anesthetics.

Thomas Engelhardt, Jamie MacDonald, Helen F. Galley, and Nigel R. Webster

Selective Phosphodiesterase 5 Inhibition Does Not Reduce Propofol Sedation Requirements but Affects Speed of Recovery and Plasma Cyclic Guanosine 3',5'-Monophosphate Concentrations in Healthy Volunteers
Anesth Analg 2005 101: 1050-1053. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Plasma cyclic guanosine 3',5'-monophosphate (cyclic GMP) concentrations are reduced during propofol sedation. Selective phosphodiesterase 5 inhibition, however, does not reduce propofol sedation requirements or plasma cyclic GMP concentrations but affects speed of recovery in healthy volunteers.

Takahiro Fujimoto, Tomoki Nishiyama, and Kazuo Hanaoka

Inhibitory Effects of Intravenous Anesthetics on Mast Cell Function
Anesth Analg 2005 101: 1054-1059. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Mast cells play an important role in the antibacterial host-defense mechanism. Thiopental, midazolam, and propofol exerted a dose-dependent inhibitory effect on mast cell chemotaxis. Ketamine, midazolam, and propofol had a dose-dependent inhibitory effect on mast cell exocytosis. The impairment of mast cell function by IV anesthetics may influence the defense against infection.

Prakash K. Dubey and Arun Kumar

Pain on Injection of Lipid-Free Propofol and Propofol Emulsion Containing Medium-Chain Triglyceride: A Comparative Study (Brief Report)
Anesth Analg 2005 101: 1060-1062. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Pain on injection of two formulations of propofol was compared. A lipid-free formulation produced more pain on injection as compared with the emulsion containing medium-chain triglyceride.

Andrea Y. A. Plate, Daune L. Crankshaw, and Daniel D. Gallaher

The Effect of Anesthesia by Diethyl Ether or Isoflurane on Activity of Cytochrome P450 2E1 and P450 Reductases in Rat Liver (Brief Report)
Anesth Analg 2005 101: 1063-1064. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Rats were anesthetized with ether, isoflurane, or carbon dioxide and liver P450 enzymes were quantified by spectrophotometry. Based on the results of this study, rats can be anesthetized with isoflurane or diethyl ether for a short period without a change in the activity of P450 enzymes.

Anil Agarwal, Mehdi Raza, Vinay Singhal, Sanjay Dhiraaj, Rakesh Kapoor, Aneesh Srivastava, Devendra Gupta, Prabhat K. Singh, Chandra Kant Pandey, and Uttam Singh

The Efficacy of Tolterodine for Prevention of Catheter-Related Bladder Discomfort: A Prospective, Randomized, Placebo-Controlled, Double-Blind Study (Brief Report)
Anesth Analg 2005 101: 1065-1067. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Bladder discomfort secondary to an indwelling urinary catheter is distressing to patients. In the present study, we observed that tolterodine (2 mg), a competitive muscarinic receptor antagonist administered 1 h before surgery, reduced both the incidence and severity of bladder discomfort secondary to bladder catheterization.

TECHNOLOGY, COMPUTING, AND SIMULATION:

Haim Berkenstadt, Gareth S. Kantor, Yakov Yusim, Naomi Gafni, Azriel Perel, Tiberiu Ezri, and Amitai Ziv

The Feasibility of Sharing Simulation-Based Evaluation Scenarios in Anesthesiology
Anesth Analg 2005 101: 1068-1074. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Simulation-based assessment tools developed in a multi-institutional study in the United States can be used in Israel despite the differences in language, education, and medical system.

Elizabeth G. VanDenKerkhof, David H. Goldstein, William C. Blaine, and Michael J. Rimmer

A Comparison of Paper with Electronic Patient-Completed Questionnaires in a Preoperative Clinic
Anesth Analg 2005 101: 1075-1080. [Abstract] [Full Text] [PDF] [Data Supplement]  [Request Permissions]  

IMPLICATIONS: Self-administered electronic health questionnaires using touchscreen computer technology are an accurate means of collecting patient information in the preoperative setting and can provide a valuable basis for an electronic perioperative patient record. Patients expressed comfort and satisfaction with this method of questionnaire completion.

Shai Efrati, Yuval Leonov, Amir Oron, Yariv Siman-Tov, Michael Averbukh, Alex Lavrushevich, and Ahuva Golik

Optimization of Endotracheal Tube Cuff Filling by Continuous Upper Airway Carbon Dioxide Monitoring
Anesth Analg 2005 101: 1081-1088. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A new, objective, noninvasive method for optimizing endotracheal tube cuff filling based on monitoring carbon dioxide levels in the upper airways can be used to identify the minimal cuff pressure necessary to eliminate leak and prevent aspiration.

Laurence van Tulder, Burkhardt Michaeli, René Chioléro, Mette M. Berger, and Jean-Pierre Revelly

An Evaluation of the Initial Distribution Volume of Glucose to Assess Plasma Volume During a Fluid Challenge (Technical Communication)
Anesth Analg 2005 101: 1089-1093. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The initial distribution volume of glucose (IDVG) is supposed to reflect effective circulating blood volume. We assessed the sensitivity of this method to a fluid challenge in patients receiving a fluid challenge, and the reproducibility in otherwise stable patients. IDVG was not sensitive to a fluid challenge, and reproducibility was poor. Thus, clinical usefulness of IDVG seems limited.

Hung-Shu Chen, Bruno Jawan, Chia-Chih Tseng, Kwok-Wai Cheng, and Chih-Hsien Wang

Difficult Ventilation with a Double-Lumen Endotracheal Tube: An Unusual Manufacturing Defect (Case Report)
Anesth Analg 2005 101: 1094-1097. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Difficult ventilation occurred during general anesthesia as the result of a manufacturing defect in both limbs of the connector of the double-lumen endotracheal tube. The problem was resolved with a careful approach, and there were no serious consequences.

PAIN MEDICINE:

Steven P. Cohen, Scott Griffith, Thomas M. Larkin, Felipe Villena, and Ralph Larkin

Presentation, Diagnoses, Mechanisms of Injury, and Treatment of Soldiers Injured in Operation Iraqi Freedom: An Epidemiological Study Conducted at Two Military Pain Management Centers
Anesth Analg 2005 101: 1098-1103. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We conducted an observational study at two large military pain treatment centers among soldiers injured in Operation Iraqi Freedom. Fifty-three percent of soldiers presented with low back pain, with lumbar herniated disk being the most common diagnosis. Only 2% of patients returned to combat duty in Iraq. To improve the return-to-duty rate, better preventive measures and more aggressive treatment in forward-deployed medical units are recommended.

G. Lynn Rasmussen, Kerstin Malmstrom, Michael H. Bourne, Maurice Jove, Steven M. Rhondeau, Paul Kotey, Jennifer Ang, Michelle Aversano, Alise S. Reicin for the Etoricoxib Postorthopedic Study Group

Etoricoxib Provides Analgesic Efficacy to Patients After Knee or Hip Replacement Surgery: A Randomized, Double-Blind, Placebo-Controlled Study
Anesth Analg 2005 101: 1104-1111. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In a postsurgery setting (knee and hip replacements), etoricoxib 120 mg provided analgesia superior to placebo and similar to controlled-release naproxen sodium 1100 mg. Patients receiving etoricoxib suffered less pain and took less opioid rescue medication compared with patients on placebo.

Yehuda Shavit, Gila Fish, Gilly Wolf, Eduard Mayburd, Ylia Meerson, Raz Yirmiya, and Benzion Beilin

The Effects of Perioperative Pain Management Techniques on Food Consumption and Body Weight After Laparotomy in Rats
Anesth Analg 2005 101: 1112-1116. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Effective perioperative pain management can improve postoperative recovery. We studied the effects of two preoperative pain management techniques on recovery after laparotomy in rats. Both analgesic treatments resulted in a faster recovery, especially preoperative analgesics combined with interleukin-1 receptor antagonist.

Takeshi Ohara, Tsunetoshi Itoh, and Masahiko Takahashi

Immunosuppression by Morphine-Induced Lymphocyte Apoptosis: Is It a Real Issue?
Anesth Analg 2005 101: 1117-1122. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Recent reports that morphine potentially induces apoptosis in human lymphocytes in vitro have raised a concern about the use of opioid-based analgesic strategies. Regarding this issue, we present rather contradictory findings that morphine has no effects on the cell expression of various apoptosis-related molecules in cultured human lymphocytes.

Mehmet D. Aydin, Mehmet Cesur, Nazan Aydin, and Haci A. Alici

Disappearance of Phantom Limb Pain During Cauda Equina Compression by Spinal Meningioma and Gradual Reactivation After Decompression (Case Report)
Anesth Analg 2005 101: 1123-1126. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We present a case in which phantom limb pain (PLP) in an amputated leg disappeared during cauda equina compression by meningioma and reactivated after surgical decompression. This case suggests that complete compression or blockade of nerves, a nerve plexus, the cauda equina, or the medullary cord may result in suppression of PLP, and decompression of or recovery from the block may cause reactivation.

ECONOMICS, EDUCATION, AND HEALTH SYSTEMS RESEARCH:

David J. Murray, John R. Boulet, Joseph F. Kras, John D. McAllister, and Thomas E. Cox

A Simulation-Based Acute Skills Performance Assessment for Anesthesia Training
Anesth Analg 2005 101: 1127-1134. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A trainee's skill in managing critical events can be assessed using a multiple scenario simulation-based performance evaluation.

CRITICAL CARE AND TRAUMA:

Keith A. Candiotti, Aimee Kamat, Paul Barach, Fani Nhuch, David Lubarsky, and David J. Birnbach

Emergency Preparedness for Biological and Chemical Incidents: A Survey of Anesthesiology Residency Programs in the United States
Anesth Analg 2005 101: 1135-1140. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In an attack involving weapons of mass destruction or toxic chemicals, anesthesiologists will provide care. Our survey of United States anesthesiology residency programs demonstrated that there is limited training of residents regarding the anesthetic management of patients injured by weapons of mass destruction. This has serious public health implications.

Jean-Paul Roustan, Sarah Valette, Pierre Aubas, Gérard Rondouin, and Xavier Capdevila

Can Electroencephalographic Analysis Be Used to Determine Sedation Levels in Critically Ill Patients?
Anesth Analg 2005 101: 1141-1151. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Spectral edge frequency 95 and Ratio 10 are the most relevant electroencephalogram (EEG) indexes for monitoring the level of sedation in intensive care unit patients but calculated EEG values exhibited large interindividual variability. Bispectral analysis of EEG provides a slight improvement over simple spectral analysis.

Yoko Kidani, Takumi Taniguchi, Hiroko Kanakura, Yasuhiro Takemoto, Kazunobu Tsuda, and Ken Yamamoto

Sevoflurane Pretreatment Inhibits Endotoxin-Induced Shock in Rats
Anesth Analg 2005 101: 1152-1156. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Sevoflurane pretreatment decreased mortality rate, severity of hypotension, and acidosis, and inhibited cytokine responses in rats injected with endotoxin, suggesting that sevoflurane may be an anesthetic of choice in endotoxemic states.

Alice Wood, Si-Mhamed Bendjelid, and Karim Bendjelid

Primary Aortoenteric Fistula: Should Enhanced Computed Tomography be Considered in the Diagnostic Work-Up? (Case Report)
Anesth Analg 2005 101: 1157-1159. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We describe the delayed diagnosis of an aortoduodenal fistula related to an abdominal aortic aneurysm. We emphasize that computed tomography scan results may be unreliable for detecting this pathology in patients who are hemodynamically unstable.

Matthias Behrends, Martin Beiderlinden, and Jürgen Peters

Acute Lung Injury After Peppermint Oil Injection (Case Report)
Anesth Analg 2005 101: 1160-1162. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This report is the first description of IV peppermint oil injection. The patient rapidly developed severe fluid overload of the lung and subsequent lung injury that required intubation, mechanical ventilation, and intensive care therapy for 13 days. The pulmonary edema was presumably caused by direct toxicity and an increase in pulmonary vascular permeability.

NEUROSURGICAL ANESTHESIA:

Hong Cao, Ira S. Kass, James E. Cottrell, and Peter J. Bergold

Pre- or Postinsult Administration of Lidocaine or Thiopental Attenuates Cell Death in Rat Hippocampal Slice Cultures Caused by Oxygen-Glucose Deprivation
Anesth Analg 2005 101: 1163-1169. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Lidocaine or thiopental applied either 10 min before or 10 min directly after oxygen-glucose deprivation reduced neuronal cell death in rat hippocampal slice cultures. Postinsult administration is often the first opportunity for treatment after stroke; lidocaine and thiopental reduced damage caused by oxygen-glucose deprivation, an in vitro model of stroke.

Edward C. Nemergut, Aaron S. Dumont, Usha T. Barry, and Edward R. Laws

Perioperative Management of Patients Undergoing Transsphenoidal Pituitary Surgery (Review Article)
Anesth Analg 2005 101: 1170-1181. [Abstract] [Full Text] [PDF] [Request Permissions]  

OBSTETRIC ANESTHESIA:

Brendan Carvalho, Sheila E. Cohen, Steven S. Lipman, Andrea Fuller, Anbu D. Mathusamy, and Alex Macario

Patient Preferences for Anesthesia Outcomes Associated with Cesarean Delivery
Anesth Analg 2005 101: 1182-1187. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Medical care can be improved by incorporating patients' preferences into medical decision making. We surveyed obstetric patients to determine their preferences regarding potential cesarean delivery anesthesia outcomes. Unlike general surgical patients who rate nausea and vomiting highest, parturients considered pain during and after cesarean delivery the most important concern.

REGIONAL ANESTHESIA:

Manuel Taboada, Jaime Rodríguez, Sabela Del Rio, Juan Lagunilla, Javier Carceller, Julián Álvarez, and Peter G. Atanassoff

Does the Site of Injection Distal to the Greater Trochanter Make a Difference in Lateral Sciatic Nerve Blockade?
Anesth Analg 2005 101: 1188-1191. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In lateral sciatic nerve blockade, a more proximal approach to the sciatic nerve provides shorter onset times and more frequent success than a more distal injection site when a single injection of 20 mL of mepivacaine 1.5% is used.

Andrea Casati, Guido Fanelli, Zbigniew Koscielniak-Nielsen, Gianluca Cappelleri, Giorgio Aldegheri, Giorgio Danelli, Régis Fuzier, and François Singelyn

Using Stimulating Catheters for Continuous Sciatic Nerve Block Shortens Onset Time of Surgical Block and Minimizes Postoperative Consumption of Pain Medication After Halux Valgus Repair as Compared with Conventional Nonstimulating Catheters
Anesth Analg 2005 101: 1192-1197. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This prospective, randomized, blind investigation demonstrated that the use of a stimulating catheter for continuous posterior popliteal sciatic nerve block resulted in shorter onset time of sensory and motor blocks and less local anesthetic consumption and need for rescue pain medication after elective orthopedic foot surgery compared with blind catheter advancement.

Vincent Minville, Roland Amathieu, N’Guyen Luc, Claude Gris, Olivier Fourcade, Kamran Samii, and Dan Benhamou

Infraclavicular Brachial Plexus Block Versus Humeral Approach: Comparison of Anesthetic Time and Efficacy
Anesth Analg 2005 101: 1198-1201. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We have compared infraclavicular brachial plexus block (ICB) with humeral block. Efficacy and anesthetic time were not significantly different, although time to perform the block was shorter with the ICB.

Ralph Lattermann, Geesche Belohlavek, Sigrid Wittmann, Bernd Füchtmeier, and Michael Gruber

The Anticatabolic Effect of Neuraxial Blockade After Hip Surgery
Anesth Analg 2005 101: 1202-1208. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We studied the effect of combined spinal/epidural blockade (CSE) on protein and glucose metabolism during and after hip surgery. In comparison to general anesthesia followed by intravenous patient-controlled analgesia, CSE inhibits the increase in glucose plasma concentration during surgery and prevents protein loss on the first postoperative day.

Mukesh Tripathi, S. S. Nath, and Rakesh K. Gupta

Paraplegia After Intracord Injection During Attempted Epidural Steroid Injection in an Awake-Patient (Case Report)
Anesth Analg 2005 101: 1209-1211. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Intracord injection of triamcinolone acetate and local anesthetic, resulting in permanent paraplegia, may occur in conscious patients.

Ban C. H. Tsui and Kevin Armstrong

Can Direct Spinal Cord Injury Occur Without Paresthesia? A Report of Delayed Spinal Cord Injury After Epidural Placement in an Awake Patient (Case Report)
Anesth Analg 2005 101: 1212-1214. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This case reminds anesthesiologists that we should not simply assume paresthesia will always occur and be reported if a needle encroaches on the spinal cord even in an awake patient.

GENERAL ARTICLES:

Punita T. Sharma, Frederick E. Sieber, Khwaja J. Zakriya, Ronald W. Pauldine, Kevin B. Gerold, Jian Hang, and Timothy H. Smith

Recovery Room Delirium Predicts Postoperative Delirium After Hip-Fracture Repair
Anesth Analg 2005 101: 1215-1220. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In patients undergoing hip-fracture repair, recovery room delirium is a strong predictor of postoperative delirium when using a standardized protocol for general anesthesia and postoperative pain management.

Conan L. McCaul, Donal Harney, Margaret Ryan, Ciaran Moran, Brian P. Kavanagh, and John F. Boylan

Airway Management in the Lateral Position: A Randomized Controlled Trial
Anesth Analg 2005 101: 1221-1225. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Inadequate airway management may be fatal. There are recommendations for airway difficulties, but the evidence favoring any specific strategy is limited. This study suggests that, in the lateral position, a laryngeal mask airway more rapidly and reliably establishes airway control than attempts at endotracheal intubation. It further suggests that placing a patient with an inadequate airway into the lateral position will hinder, not help, airway management.

Jong-Hwan Lee, Chang-Hee Kim, Jae-Hyon Bahk, and Kum-Suk Park

The Influence of Endotracheal Tube Tip Design on Nasal Trauma During Nasotracheal Intubation: Magill-Tip Versus Murphy-Tip
Anesth Analg 2005 101: 1226-1229. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: During nasotracheal intubation with conventional endotracheal tubes, Magill-tipped, nonthermosoftened tubes seem to be comparable to Murphy-tipped, thermosoftened tubes with regard to trauma on the nasal mucosa.

Anil Agarwal, P. K. Sinha, Manish Tandon, Sanjay Dhiraaj, and Uttam Singh

Evaluating the Efficacy of the Valsalva Maneuver on Venous Cannulation Pain: A Prospective, Randomized Study
Anesth Analg 2005 101: 1230-1232. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Venous cannulation is a necessary step for safe anesthesia administration; however, the pain associated with it is sometimes very distressing. We observed that the Valsalva maneuver performed at the time of venous cannulation greatly decreases this pain.

Spyros D. Mentzelopoulos, Maria Tzoufi, Kostas Rellos, Argyris S. Michalopoulos, Elissavet Stamataki, Charris Roussos, and Spyros G. Zakynthinos

An Evaluation of McCoy Balloon Laryngoscopy in Patients With Moderate-to-Major Endotracheal Intubation Difficulty
Anesth Analg 2005 101: 1233-1237. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study shows that, in patients with moderate-to-major conventional airway management difficulty, combined McCoy-balloon laryngoscopy results in improved laryngoscopic/intubating conditions when compared with the conventional, McCoy, and balloon laryngoscopic techniques. McCoy-balloon laryngoscopy combines the merits of McCoy and balloon laryngoscopy and can be recommended for patients with moderate-to-major intubation difficulty.

LETTER TO THE EDITOR:

Warren J. Levy

Is Anesthetic-Related Mortality a Statistical Illness?
Anesth Analg 2005 101: 1238. [Full Text] [PDF] [Request Permissions]  

Arnold J. Berry

Observational Studies Identify Associations, Not Causality
Anesth Analg 2005 101: 1238. [Full Text] [PDF] [Request Permissions]  

John C. Drummond and Piyush M. Patel

Editorial Board Reproached for Publication of BIS-Mortality Correlation
Anesth Analg 2005 101: 1238-1239. [Full Text] [PDF] [Request Permissions]  

Terri G. Monk, B. Craig Weldon, Vikas Saini, and Jeffrey C. Sigl

Editorial Board Reproached for Publication of BIS-Mortality Correlation
Anesth Analg 2005 101: 1239-1240. [Full Text] [PDF] [Request Permissions]  

Neal Cohen

Editorial Board Reproached for Publication of BIS-Mortality Correlation
Anesth Analg 2005 101: 1240. [Full Text] [PDF] [Request Permissions]  

Philip J. Balestrieri

Epidural Chloroprocaine-Standard of Care for Postpartum Bilateral Tubal Ligation
Anesth Analg 2005 101: 1241. [Full Text] [PDF] [Request Permissions]  

Kenneth Drasner

Epidural Chloroprocaine-Standard of Care for Postpartum Bilateral Tubal Ligation
Anesth Analg 2005 101: 1241. [Full Text] [PDF] [Request Permissions]  

Guillermo Lema and Nicolás Aeschlimann

To Dilate or Not To Dilate
Anesth Analg 2005 101: 1241-1242. [Full Text] [PDF] [Request Permissions]  

Giorgio Della Rocca and L. Pompei

To Dilate or Not To Dilate
Anesth Analg 2005 101: 1242. [Full Text] [PDF] [Request Permissions]  

Zorica Jankovic, Dusica Stamenkovic, and Wafaa Abdel-Hadi

Chronic Intrapleural Effusion Drainage Using an Epidural Catheter
Anesth Analg 2005 101: 1242. [Full Text] [PDF] [Request Permissions]  

Hector J. Lacassie and Adeyemi J. Olufolabi

Remifentanil for Labor Pain: Is the Drug or the Method the Problem?
Anesth Analg 2005 101: 1242-1243. [Full Text] [PDF] [Request Permissions]  

Shmuel Evron and Tiberiu Ezri

Remifentanil for Labor Pain: Is the Drug or the Method the Problem?
Anesth Analg 2005 101: 1243. [Full Text] [PDF] [Request Permissions]  

Jens Lohser and Jay B. Brodsky

Tracheal Perforation from Double-Lumen Tubes: Size May Be Important
Anesth Analg 2005 101: 1243-1244. [Full Text] [PDF] [Request Permissions]  

Govind R. Rajan

Tracheal Perforation from Double-Lumen Tubes: Size May Be Important
Anesth Analg 2005 101: 1244-1245. [Full Text] [PDF] [Request Permissions]  

Hwan Joo and Viren Naik

Conventional Tracheal Tubes for Intubation through the Intubating Laryngeal Mask Airway
Anesth Analg 2005 101: 1245. [Full Text] [PDF] [Request Permissions]  

Pankaj Kundra, N. Sujata, and M. Ravishankar

Conventional Tracheal Tubes for Intubation through the Intubating Laryngeal Mask Airway
Anesth Analg 2005 101: 1245. [Full Text] [PDF] [Request Permissions]  

Peter Szmuk, Oscar Ghelber, and Tiberiu Ezri

Difficult Intubation in Thoracopagus Twins in MRI Suite
Anesth Analg 2005 101: 1246. [Full Text] [PDF] [Request Permissions]  

Erik S. Shank and Ulrich Schmidt

Difficult Intubation in Thoracopagus Twins in MRI Suite
Anesth Analg 2005 101: 1246. [Full Text] [PDF] [Request Permissions]  

Philippe E. Dubois, Maximilien J. Gourdin, and Jacques Jamart

Assessment of Neuromuscular Blockade Using Acceleromyography Should Be Performed Before Emergence from Anesthesia
Anesth Analg 2005 101: 1246-1247. [Full Text] [PDF] [Request Permissions]  

Christophe Baillard

Assessment of Neuromuscular Blockade Using Acceleromyography Should Be Performed Before Emergence from Anesthesia
Anesth Analg 2005 101: 1247. [Full Text] [PDF] [Request Permissions]  

Chol Kim, Atsuhiro Sakamoto, and Ryo Ogawa

Effect of Landiolol on Nonsustained Ventricular Tachycardia During Electroconvulsive Therapy
Anesth Analg 2005 101: 1247. [Full Text] [PDF] [Request Permissions]  

Ahed Zeidan

Can’t Blame Ropivacaine
Anesth Analg 2005 101: 1247. [Full Text] [PDF] [Request Permissions]  

M. K. Panni

Can’t Blame Ropivacaine
Anesth Analg 2005 101: 1247-1248. [Full Text] [PDF] [Request Permissions]  

Edmund H. Jooste, Susumu Ohkawa, and Lena S. Sun

Fiberoptic Intubation with Dexmedetomidine in Two Children with Spinal Cord Impingements
Anesth Analg 2005 101: 1248. [Full Text] [PDF] [Request Permissions]  

Robert T. M. van Dongen and Bas M. Gerritse

Epidural Blood Patch in Varicella Infection
Anesth Analg 2005 101: 1248. [Full Text] [PDF] [Request Permissions]  

David P. Martin

Epidural Blood Patch in Varicella Infection
Anesth Analg 2005 101: 1248. [Full Text] [PDF] [Request Permissions]  

BOOK AND MULTIMEDIA REVIEWS:

Michael J. Murray

Textbook of Critical Care, 5th Ed.
Anesth Analg 2005 101: 1249. [Full Text] [PDF] [Request Permissions]  

Robert E. Johnstone

Essential Anesthesia: From Science to Practice.
Anesth Analg 2005 101: 1249-1250. [Full Text] [PDF] [Request Permissions]  

Norig Ellison

Pentathol Postcards
Anesth Analg 2005 101: 1250. [Full Text] [PDF] [Request Permissions]  

ERRATA:

Erratum
Anesth Analg 2005 101: 965. [Full Text] [PDF] [Request Permissions]  

Erratum
Anesth Analg 2005 101: 1011. [Full Text] [PDF] [Request Permissions]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.