GUEST REVIEWER LIST:

GUEST REVIEWER LIST April 1, 2005–September 30, 2005
Anesth Analg 2005 101: 1-4. [Full Text] [PDF] [Request Permissions]  

AUTHOR INDEX:

Author Index to Volume 101
Anesth Analg 2005 101: 5-26. [Full Text] [PDF] [Request Permissions]  

SUBJECT INDEX:

Subject Index to Volume 101
Anesth Analg 2005 101: 27-51. [Full Text] [PDF] [Request Permissions]  

CARDIOVASCULAR ANESTHESIA:

Matthias L. Riess, Amadou K. S. Camara, Samhita S. Rhodes, Joseph McCormick, Ming T. Jiang, and David F. Stowe

Increasing Heart Size and Age Attenuate Anesthetic Preconditioning in Guinea Pig Isolated Hearts
Anesth Analg 2005 101: 1572-1576. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Larger and older Langendorff-prepared guinea pig hearts are less susceptible to cardioprotection against ischemia/reperfusion injury by preconditioning with volatile anesthetics than are smaller and younger hearts. This may have important implications for further basic science research on anesthetic preconditioning and its possible clinical applicability in humans.

Claus U. Niemann, Ryutaro Hirose, Tao Liu, Matthias Behrends, Jaimi L. Brown, Douglas F. Kominsky, John P. Roberts, and Natalie Serkova

Ischemic Preconditioning Improves Energy State and Transplantation Survival in Obese Zucker Rat Livers
Anesth Analg 2005 101: 1577-1583. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Ischemic preconditioning improves hepatic energy metabolism during cold ischemia. Rats receiving a liver transplant from an obese rat demonstrate improved survival when ischemic preconditioning is used.

Hideo Hashiguchi, Hiroaki Morooka, Hiroshi Miyoshi, Masanori Matsumoto, Takehiko Koji, and Koji Sumikawa

Isoflurane Protects Renal Function Against Ischemia and Reperfusion Through Inhibition of Protein Kinases, JNK and ERK
Anesth Analg 2005 101: 1584-1589. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We have shown that isoflurane produces pharmacological preconditioning against renal ischemia/reperfusion injury in the rat kidney similar to that in the heart. Inhibition of the protein kinases, JNK and ERK, appears to be one of the mechanisms involved. Isoflurane might therefore be beneficial in patients at risk of renal ischemia/reperfusion.

John G. Krolikowski, Martin Bienengraeber, Dorothee Weihrauch, David C. Warltier, Judy R. Kersten, and Paul S. Pagel

Inhibition of Mitochondrial Permeability Transition Enhances Isoflurane-Induced Cardioprotection During Early Reperfusion: The Role of Mitochondrial K_ATP Channels
Anesth Analg 2005 101: 1590-1596. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Inhibition of the mitochondrial permeability transition pore enhances, whereas opening abolishes, reductions in myocardial infarct size produced by isoflurane when this volatile anesthetic is administered immediately before and during early reperfusion in rabbits. This isoflurane-induced inhibition of mitochondrial permeability transition is dependent on activation of mitochondrial KATP channels.

Toshiyuki Sawai, Toshihiro Nohmi, Yoshihiko Ohnishi, Yuji Takauchi, and Masakazu Kuro

Cardiac Output Measurement Using the Transesophageal Doppler Method Is Less Accurate Than the Thermodilution Method When Changing Paco₂
Anesth Analg 2005 101: 1597-1601. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS:Cardiac output measurement using the transesophageal Doppler method is as accurate as thermodilution, although it is less accurate at a higher Paco2 level. The present study has shown that both methods of measurement agree with each other at 30 mm Hg of Paco2, but the thermodilution method provides higher cardiac output values than the transesophageal Doppler method at 40 mm Hg of Paco2.

Toshiya Shiga, Zen’ichiro Wajima, Tetsuo Inoue, and Atsuhiro Sakamoto

Aprotinin in Major Orthopedic Surgery: A Systematic Review of Randomized Controlled Trials
Anesth Analg 2005 101: 1602-1607. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A meta-analysis of 13 randomized controlled trials showed that aprotinin reduces intraoperative and perioperative blood loss and blood transfusion requirements but is not associated with an increased risk of deep vein thrombosis in the presence of prophylaxis.

Adam B. Lerner, Eswar Sundar, Feroze Mahmood, Todd Sarge, Douglas W. Hanto, and Peter J. Panzica

Four Cases of Cardiopulmonary Thromboembolism During Liver Transplantation Without the Use of Antifibrinolytic Drugs (Case Report)
Anesth Analg 2005 101: 1608-1612. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: These four case reports add to the 23 previously reported cases of cardiopulmonary thromboembolism during liver transplantation. These devastating events occurred without the use of an antifibrinolytic drug.

Brian Fitzsimons and Colleen G. Koch

Parachute Mitral Valve (Echo Rounds)
Anesth Analg 2005 101: 1613-1614. [Full Text] [PDF] [Data Supplement]  [Request Permissions]  

PEDIATRIC ANESTHESIA:

Teruhiko Ishikawa, Shiroh Isono, Atsuko Tanaka, Yugo Tagaito, and Takashi Nishino

Airway Protective Reflexes Evoked by Laryngeal Instillation of Distilled Water Under Sevoflurane General Anesthesia in Children
Anesth Analg 2005 101: 1615-1618. [Abstract] [Full Text] [PDF] [Data Supplement]  [Request Permissions]  

IMPLICATIONS: Some of the upper airway troubles during anesthesia are related to airway protective reflexes evoked from the larynx. Sevoflurane should modify these reflexes; however, systematic studies have never been performed in children. Fiberoptic visual observation was combined with conventional pressure measurements to evaluate detailed responses of the larynx in sevoflurane-anesthetized children.

Simonetta Tesoro, Daniele Mezzetti, Laura Marchesini, and Vito Aldo Peduto

Clonidine Treatment for Agitation in Children After Sevoflurane Anesthesia
Anesth Analg 2005 101: 1619-1622. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The administration of IV clonidine to children anesthetized with sevoflurane reduces the incidence of agitation at emergence.

Doralina L. Anghelescu, Laura L. Burgoyne, Linda L. Oakes, and Debora A. Wallace

The Safety of Patient-Controlled Analgesia by Proxy in Pediatric Oncology Patients
Anesth Analg 2005 101: 1623-1627. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study showed that patient-controlled analgesia (PCA) by proxy for children with cancer is a safe practice with infrequent respiratory and neurological complications. Patient selection criteria, educational programs for parents, and specific documentation are described as steps to ensure the safety of PCA by proxy.

Adarsh B. Lal, Ram Maruthavanan, and Nicholas B. Scott

Aortic Valve Repair in a Patient with Congenital Afibrinogenemia (Case Report)
Anesth Analg 2005 101: 1628-1630. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by unmeasurable fibrinogen, inability of blood to clot, and confounded by reports of thrombosis. Cardiopulmonary bypass can be effectively managed by heparinization and aprotinin to preserve clotting factors and cryoprecipitate as a source for fibrinogen.

AMBULATORY ANESTHESIA:

Admir Hadzic

Is Regional Anesthesia Really Better than General Anesthesia? (Editorial)
Anesth Analg 2005 101: 1631-1633. [Full Text] [PDF] [Request Permissions]  

Spencer S. Liu, Wyndam M. Strodtbeck, Jeffrey M. Richman, and Christopher L. Wu

A Comparison of Regional Versus General Anesthesia for Ambulatory Anesthesia: A Meta-Analysis of Randomized Controlled Trials
Anesth Analg 2005 101: 1634-1642. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This meta-analysis suggests that regional anesthesia offers several advantages over general anesthesia for ambulatory surgery, such as decreased postanesthesia care unit use, nausea, and postoperative pain. Although these advantages are thought to hasten patient recovery, patients were not discharged sooner from the ambulatory surgical unit.

Kristiina Mattila, Juhani Toivonen, Leena Janhunen, Per H. Rosenberg, and Markku Hynynen

Postdischarge Symptoms After Ambulatory Surgery: First-Week Incidence, Intensity, and Risk Factors
Anesth Analg 2005 101: 1643-1650. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Postdischarge minor morbidity in 2732 outpatients was found to be common during the first postoperative week. The identification of postoperative problems and related risk factors may aid anesthesiologists in choosing appropriate preventive strategies and to plan future research for the evaluation of the patients' functional impairment after ambulatory surgery.

Dirk H. van Zijl, Peter C. Gordon, and Michael F. James

The Comparative Effects of Remifentanil or Magnesium Sulfate Versus Placebo on Attenuating the Hemodynamic Responses After Electroconvulsive Therapy
Anesth Analg 2005 101: 1651-1655. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Either remifentanil 1.0 {micro}g/kg or magnesium sulfate (MgSO4) 30 mg/kg may be used as part of a standard general anesthetic technique to attenuate the systolic arterial blood pressure response to electroconvulsive therapy. Remifentanil, but not MgSO4, suppressed the increase in heart rate. Neither drug influenced seizure duration.

Ron Flaishon, Perla Ekstein, Haim Matzkin, and Avi A. Weinbroum

An Evaluation of General and Spinal Anesthesia Techniques for Prostate Brachytherapy in a Day Surgery Setting (Brief Report)
Anesth Analg 2005 101: 1656-1658. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Total IV anesthesia (TIVA), general anesthesia with isoflurane and fentanyl, 5 mg of bupivacaine 0.5%, and 2.5 mg of bupivacaine 0.5% plus 25 {micro}g of fentanyl spinal techniques are suitable for transperineal brachytherapy for prostate cancer in the day-surgery setting. TIVA allows for the earliest discharge home because of its allowing for earlier voiding. Between the two spinal techniques, the combination of spinal bupivacaine plus fentanyl allows for earlier voiding and home readiness.

Marc Beaussier, Henri Weickmans, Zoubida Abdelhalim, and André Lienhart

Inguinal Herniorrhaphy Under Monitored Anesthesia Care with Ilioinguinal-Iliohypogastric Block: The Impact of Adding Clonidine to Ropivacaine (Brief Report)
Anesth Analg 2005 101: 1659-1662. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The benefit of adding clonidine 75 {micro}g to ropivacaine 225 mg (7.5 mg/mL) for ilioinguinal-iliohypogastric block in adult patients operated on for inguinal hernia repair is to reduce motion pain on the third postoperative day. This benefit must be balanced with an awareness of an increasing risk of orthostatic hypotension in the immediate postoperative period.

Stephen M. Klein, Holly Evans, Karen C. Nielsen, Marcy S. Tucker, David S. Warner, and Susan M. Steele

Peripheral Nerve Block Techniques for Ambulatory Surgery (Review Article)
Anesth Analg 2005 101: 1663-1676. [Abstract] [Full Text] [PDF] [Request Permissions]  

ANESTHETIC PHARMACOLOGY:

Thomas J. Ebert, David J. Ficke, Shahbaz R. Arain, Melissa N. Holtz, and Hariharan Shankar

Vasodilation from Sufentanil in Humans
Anesth Analg 2005 101: 1677-1680. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Sufentanil has a dose-dependent, direct, vasodilatory effect on human vascular tissue.

Atsushi Kohjitani, Makoto Funahashi, Takuya Miyawaki, Motohiko Hanazaki, Ryuji Matsuo, and Masahiko Shimada

Peripheral N-Methyl-d-Aspartate Receptors Modulate Nonadrenergic Noncholinergic Lower Esophageal Sphincter Relaxation in Rabbits
Anesth Analg 2005 101: 1681-1688. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Our findings suggest that anesthetics may affect lower esophageal sphincter motility by modulating nitric oxide-mediated physiological relaxation through peripheral N-methyl-d-aspartate receptors in clinical situations.

Kiyokazu Kagawa, Yukio Hayashi, Isao Itoh, Mitsuo Iwasaki, Koji Takada, Takahiko Kamibayashi, Atsushi Yamatodani, and Takashi Mashimo

Identification of the Central Imidazoline Receptor Subtype Involved in Modulation of Halothane-Epinephrine Arrhythmias in Rats
Anesth Analg 2005 101: 1689-1694. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Imidazoline receptors in the central nervous system are subclassified as I1 and I2 subtypes. We examined which imidazoline receptor subtype is involved in the halothane-epinephrine-induced arrhythmias. Our results show that central I1, but not I2, receptors play an important role in inhibition of halothane-epinephrine arrhythmia.

Tobias Podranski, Thomas Bouillon, Peter M. Schumacher, Akikio Taguchi, Daniel I. Sessler, and Andrea Kurz

Compartmental Pharmacokinetics of Dantrolene in Adults: Do Malignant Hyperthermia Association Dosing Guidelines Work?
Anesth Analg 2005 101: 1695-1699. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Dantrolene is the drug of choice for treatment of malignant hyperthermia and malignant neuroleptic syndrome. Current dosing recommendations are based on noncompartmental analyses. This study determines the compartmental pharmacokinetics of dantrolene, models current dosing recommendations, and proposes an infusion regime to maintain constant plasma concentrations.

Thomas Ledowski, Berthold Bein, Robert Hanss, Andrea Paris, Wolfgang Fudickar, Jens Scholz, and Peter H. Tonner

Neuroendocrine Stress Response and Heart Rate Variability: A Comparison of Total Intravenous Versus Balanced Anesthesia
Anesth Analg 2005 101: 1700-1705. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Intraoperative stress is one of the key factors of outcome. We compared intraoperative stress during balanced and total IV anesthesia using plasma levels of stress hormones and heart rate variability for assessment. The results indicate a higher sympathetic outflow during balanced anesthesia.

Yuki Sato, Norimasa Seo, and Eiji Kobahashi

The Dosing-Time Dependent Effects of Intravenous Hypnotics in Mice (Brief Report)
Anesth Analg 2005 101: 1706-1708. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Hypnotic duration of ketamine, pentobarbital, propofol, midazolam, and ethanol showed significant dosing-time dependency in mice.

R. Michael Ritchey, Robert F. Helfand, Samuel A. Irefin, Maged Argalious, and John E. Tetzlaff

Hetastarch Allergy and Positive Latex Radioallergosorbent Test in a Patient Suffering Cardiovascular Decompensation During Multiple Perioperative Periods (Case Report)
Anesth Analg 2005 101: 1709-1712. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We report a case of a patient suffering cardiovascular decompensation during four nonconsecutive perioperative periods, ultimately found to have an allergy to hetastarch, while also manifesting a very highly positive latex radioallergosorbent test.

TECHNOLOGY, COMPUTING, AND SIMULATION:

Ngai Liu, Thierry Chazot, Isabelle Huybrechts, Jean-Dominique Law-Koune, Luc Barvais, and Marc Fischler

The Influence of a Muscle Relaxant Bolus on Bispectral and Datex-Ohmeda Entropy Values During Propofol-Remifentanil Induced Loss of Consciousness
Anesth Analg 2005 101: 1713-1718. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: During light anesthesia, electromyographic activity is high and myorelaxant bolus administration decreases bispectral index and response entropy values.

Jessie Y. C. Ng, Jo C. F. Man, Sidney Fels, Guy Dumont, and J. Mark Ansermino

An Evaluation of a Vibro-Tactile Display Prototype for Physiological Monitoring
Anesth Analg 2005 101: 1719-1724. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The cognitive ability of the clinician has been overloaded by the exponential growth of physiological monitoring devices and a large percentage of false alarms in an operating room. This study investigated the possibility of using a vibro-tactile display to replace visual and audio alarms for conveying physiological information.

Jonathan D. Katz

Radiation Exposure to Anesthesia Personnel: The Impact of an Electrophysiology Laboratory (Brief Report)
Anesth Analg 2005 101: 1725-1726. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Anesthesiologists are at risk for occupational exposure to radiation during a number of diagnostic and therapeutic procedures. This study reports on the increase in radiation exposure to a small department of anesthesiology subsequent to the introduction of an electrophysiology laboratory.

PAIN MEDICINE:

Igor Kissin

Tolerance to Opioid Analgesia: Why Do We Differ from Rats? (Editorial)
Anesth Analg 2005 101: 1727-1729. [Full Text] [PDF] [Request Permissions]  

Ahmet Dogrul, Edward J. Bilsky, Michael H. Ossipov, Josephine Lai, and Frank Porreca

Spinal L-Type Calcium Channel Blockade Abolishes Opioid-Induced Sensory Hypersensitivity and Antinociceptive Tolerance
Anesth Analg 2005 101: 1730-1735. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Long-term morphine administration causes hypersensitivity sensory stimuli, which presents as behavioral signs indicative of enhanced pain. Morphine-induced hyperesthesias may drive antinociceptive tolerance. A L-type calcium channel blocker, amlodipine, abolishes these morphine-induced hypersensitivities and antinociceptive tolerance and may represent a therapeutic advantage in the treatment of chronic pain states.

James P. Rathmell and Jane C. Ballantyne

Local Anesthetics for the Treatment of Neuropathic Pain: On the Limits of Meta-Analysis (Editorial)
Anesth Analg 2005 101: 1736-1737. [Full Text] [PDF] [Request Permissions]  

Ivo W. Tremont-Lukats, Vidya Challapalli, Ewan D. McNicol, Joseph Lau, and Daniel B. Carr

Systemic Administration of Local Anesthetics to Relieve Neuropathic Pain: A Systematic Review and Meta-Analysis
Anesth Analg 2005 101: 1738-1749. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Systemic administration of local anesthetics is superior to placebo and as effective as other analgesics commonly used for neuropathic pain. This benefit is greatest for pain from trauma, diabetes, and central pain.

Alain C. Van Elstraete, Philippe Sitbon, Fabien Trabold, Jean-Xavier Mazoit, and Dan Benhamou

A Single Dose of Intrathecal Morphine in Rats Induces Long-Lasting Hyperalgesia: The Protective Effect of Prior Administration of Ketamine
Anesth Analg 2005 101: 1750-1756. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A single intrathecal injection of morphine in rats produced a delayed and sustained hyperalgesia linked to the development of opioid-induced pain sensitivity. The noncompetitive N-methyl-d-aspartate-receptor antagonist ketamine almost completely prevented morphine-induced hyperalgesia.

Markus Klass, Allen Hord, Melissa Wilcox, Don Denson, and Marie Csete

A Role for Endothelin in Neuropathic Pain After Chronic Constriction Injury of the Sciatic Nerve
Anesth Analg 2005 101: 1757-1762. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Neuropathic pain is poorly understood at the molecular level. Using chronic constriction injury of rat sciatic nerve, we show that the vasoactive hormone endothelin (ET)-1 is involved in establishing pain, which can be treated acutely by blockade of ETA receptor activity. ETA antagonism may be a novel therapy for neuropathic pain.

Nara L. M. Quintão, Rodrigo Medeiros, Adair R.S. Santos, Maria M. Campos, and João B. Calixto

The Effects of Diacerhein on Mechanical Allodynia in Inflammatory and Neuropathic Models of Nociception in Mice
Anesth Analg 2005 101: 1763-1769. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The present work assesses, for the first time, the antiallodynic effects of diacerhein, a drug used clinically in some countries for the treatment of osteoarthritis, in inflammatory and neuropathic animal models of nociception. In all experiments, the effects of diacerhein were compared to those of gabapentin.

CRITICAL CARE AND TRAUMA:

Joachim H. Zdolsek, Björn Lisander, and Robert G. Hahn

Measuring the Size of the Extracellular Fluid Space Using Bromide, Iohexol, and Sodium Dilution
Anesth Analg 2005 101: 1770-1777. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Bromide is compared with two new tracers, iohexol and sodium dilution, for measurement of the extracellular fluid volume. The new methods are more easily applied in the clinical environment.

Martin W. Dünser, Andreas J. Mayr, Guido Hinterberger, Cornelia Lass Flörl, Hanno Ulmer, Stefan Schmid, Barbara Friesenecker, Ingo Lorenz, and Walter R. Hasibeder

Central Venous Catheter Colonization in Critically Ill Patients: A Prospective, Randomized, Controlled Study Comparing Standard with Two Antiseptic-Impregnated Catheters
Anesth Analg 2005 101: 1778-1784. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Sepsis originating from infected intravascular devices is a major cause of morbidity and extra costs. Antiseptic-impregnated central venous catheters (CVC) could not prevent catheter colonization when compared with standard catheters in a critical care setting with infrequent catheter colonization rates and CVC left in place for >10 days.

Evandro L.A. Ferreira, Renato G.G. Terzi, William A. Silva, and Ana C. de Moraes

Early Colloid Replacement Therapy in a Near-Fatal Model of Hemorrhagic Shock
Anesth Analg 2005 101: 1785-1791. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Pigs in hemorrhagic shock (severe enough to induce lactic acidosis) were resuscitated either with a synthetic oncotic solution of hydroxyethyl starch (colloid) or with an ionic isotonic solution (crystalloid). Variables expressing circulatory and tissue perfusion recovery demonstrated better performance of colloid when compared with crystalloid.

Pekka Loisa, Ari Uusaro, and Esko Ruokonen

A Single Adrenocorticotropic Hormone Stimulation Test Does Not Reveal Adrenal Insufficiency in Septic Shock
Anesth Analg 2005 101: 1792-1798. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In this prospective study two consecutive adrenocorticotropic hormone (ACTH) stimulation tests were performed in 60 critically ill patients. In a subgroup of septic shock patients the test results were poorly reproducible. This suggests that the ACTH stimulation test is not a sensitive method to diagnose adrenal insufficiency in septic shock patients.

Hirofumi Nagata, Takashi Horiguchi, Keiji Enzan, Toshiaki Nishikawa, and Kenji Suzuki

Inhibition of Poly (ADP-ribose) Synthetase Improves Pulmonary Arterial Endothelium-Dependent Relaxation After Ischemic-Reperfusion Injury of Splanchnic Artery in Rats
Anesth Analg 2005 101: 1799-1804. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Inhibition of poly (adenosine diphosphate [ADP]-ribose) synthetase improves pulmonary arterial endothelium-dependent relaxation after ischemic-reperfusion injury of the splanchnic artery.

Elke G. Czeslick, Frank Nestler, Andreas Simm, Anja Struppert, and Armin Sablotzki

Drotrecogin Alfa (Activated) Does Not Affect Intracellular Production of Interleukin-6 and Tumor Necrosis Factor- in Endotoxin-Stimulated Human Monocytes (Brief Report)
Anesth Analg 2005 101: 1805-1808. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The objective of this laboratory ex vivo study was to investigate the effects of drotrecogin alfa (activated, a recombinant human activated protein C) for the first time on intracellular expression of interleukin-6 and tumor necrosis factor α of lipopolysaccharide-stimulated human monocytes in a whole blood system assessed by flow cytometry.

Sebastian Schulz-Stübner

The Use of Small-Dose Theophylline for the Treatment of Bradycardia in Patients with Spinal Cord Injury (Case Report)
Anesth Analg 2005 101: 1809-1811. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Small-dose theophylline might be an interesting adjunct for the treatment of spinal cord injury-evoked bradycardia and respiratory dysfunction.

NEUROSURGICAL ANESTHESIA:

Sethuraman Manikandan, Praveen Kumar Neema, and Ramesh Chandra Rathod

Airway Problems Caused by Hypogonadism in Male Patients Undergoing Neurosurgery (Case Report)
Anesth Analg 2005 101: 1812-1815. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Impaired growth and development of the upper airway in male hypogonadism patients, caused by delayed sexual maturation during puberty, can cause problems in securing the airway for the conduct of general anesthesia.

OBSTETRIC ANESTHESIA:

Yukio Hayashi, Hiroshi Ueyama, Takashi Mashimo, Kenji Kangawa, and Naoto Minamino

Circulating Mature Adrenomedullin Is Related to Blood Volume in Full-Term Pregnancy
Anesth Analg 2005 101: 1816-1820. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Mature adrenomedullin is a potent vasodilating peptide. We demonstrated that plasma-mature adrenomedullin concentration increased and that increased plasma-mature adrenomedullin is associated with increased blood volume during pregnancy.

Miriam J. Harnett, Mary E. Walsh, Thomas F. McElrath, and Lawrence C. Tsen

The Use of Central Neuraxial Techniques in Parturients with Factor V Leiden Mutation (Case Report)
Anesth Analg 2005 101: 1821-1823. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Factor V Leiden has significant anesthetic implications throughout pregnancy.

REGIONAL ANESTHESIA:

Michael J. Barrington, David Olive, Keng Low, David A. Scott, Jennifer Brittain, and Peter Choong

Continuous Femoral Nerve Blockade or Epidural Analgesia After Total Knee Replacement: A Prospective Randomized Controlled Trial
Anesth Analg 2005 101: 1824-1829. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In this study, femoral nerve infusions and epidural infusions provided equivalent analgesia and postoperative rehabilitation after total knee replacement. Femoral nerve blockade was associated with less nausea and vomiting.

Etienne de Medicis, Jean-Pierre Tetrault, Rene Martin, Remi Robichaud, and Lucie Laroche

A Prospective Comparative Study of Two Indirect Methods for Confirming the Localization of an Epidural Catheter for Postoperative Analgesia
Anesth Analg 2005 101: 1830-1833. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We prospectively compared 2 different tests that predict whether an epidural catheter insertion will be successful to see if one was better. The epidural stimulation test and the epidural pressure wave analysis were found to be equivalent.

Chen-Hwan Cherng, Chih-Ping Yang, and Chih-Shung Wong

Epidural Fentanyl Speeds the Onset of Sensory and Motor Blocks During Epidural Ropivacaine Anesthesia
Anesth Analg 2005 101: 1834-1837. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The addition of 100 {micro}g fentanyl to 1% ropivacaine solution accelerated the onset of sensory and motor blocks during epidural ropivacaine anesthesia without significant fentanyl-related side effects.

Caryn S. Barnet, David N. Louis, and Daniel S. Kohane

Tissue Injury from Tricyclic Antidepressants Used as Local Anesthetics
Anesth Analg 2005 101: 1838-1843. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Tissue toxicity of tricyclic antidepressants was studied in a rat model of sciatic nerve blockade. It was found that amitriptyline and doxepin cause severe local tissue injury.

Wolfgang G. Voelckel, Günther Klima, Anette C. Krismer, Christopher Haslinger, Karl H. Stadlbauer, Volker Wenzel, and Achim von Goedecke

Signs of Inflammation After Sciatic Nerve Block in Pigs (Brief Report)
Anesth Analg 2005 101: 1844-1846. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Nerve trauma remains a major concern of regional anesthesia. Results from this pilot study in pigs suggest that very low current stimulation (<0.2 mA) before injection of bupivacaine might be associated with an increased risk of inflammatory response compared with a motor response achieved with a current between 0.3 and 0.5 mA.

Thouraya Chabbouh, Claude Lentschener, Mathieu Zuber, Nicole Jude, Bernard Delaitre, and Yves Ozier

Persistent Cauda Equina Syndrome with No Identifiable Facilitating Condition After an Uneventful Single Spinal Administration of 0.5% Hyperbaric Bupivacaine (Case Report)
Anesth Analg 2005 101: 1847-1848. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A case of persistent cauda equina syndrome after uneventful single intrathecal administration of bupivacaine, in the absence of any predisposing factors, is reported. This report suggests the need to follow up all patients undergoing regional anesthesia procedures to assess infrequent complications, including unexpected persistent neurologic deficit.

GENERAL ARTICLES:

Leopold H. J. Eberhart, Friederike Döderlein, Gudrun Eisenhardt, Peter Kranke, Daniel I. Sessler, Alexander Torossian, Hinnerk Wulf, and Astrid M. Morin

Independent Risk Factors for Postoperative Shivering
Anesth Analg 2005 101: 1849-1857. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Postoperative shivering can be predicted with acceptable accuracy using the four risk factors identified in the present study. The presented model may serve as a clinical tool to help clinicians to rationally administer prophylactic antishivering drugs.

Lawrence T. Goodnough, Aryeh Shander, Jerry L. Spivak, Jonathan H. Waters, Arnold J. Friedman, Jeffrey L. Carson, E. Michael Keating, Thomas Maddox, and Richard Spence

Detection, Evaluation, and Management of Anemia in the Elective Surgical Patient
Anesth Analg 2005 101: 1858-1861. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Up to 35% of patients scheduled for elective surgery are found to be anemic (hemoglobin <13.0 g/dL) on preadmission testing. There are no guidelines for the evaluation and management for these patients. To address this unmet medical need, a panel of multidisciplinary experts was convened. A clinical care pathway for the screening, evaluation, and management of anemia in the elective surgery patient is presented.

Carin A. Hagberg, Frank Samsoe Jensen, Harald V. Genzwuerker, Renée Krivosic-Horber, Bettina U. Schmitz, Jochen Hinkelbein, Marius Contzen, Herve Menu, and Karim Bourzoufi

A Multicenter Study of the Ambu® Laryngeal Mask in Nonparalyzed, Anesthetized Patients
Anesth Analg 2005 101: 1862-1866. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The clinical performance and safety of the new, disposable Ambu laryngeal mask airway was evaluated in an international multicenter study of 118 patients. This device is easy to insert and provides an efficient seal during positive pressure ventilation in nonparalyzed elective surgical patients under general anesthesia.

Akira Kudoh

Perioperative Management for Chronic Schizophrenic Patients (Review Article)
Anesth Analg 2005 101: 1867-1872. [Abstract] [Full Text] [PDF] [Request Permissions]  

Yuka Noto, Tetsumi Sato, Mihoko Kudo, Kiyoshi Kurata, and Kazuyoshi Hirota

The Relationship Between Salivary Biomarkers and State-Trait Anxiety Inventory Score Under Mental Arithmetic Stress: A Pilot Study. (Brief Report)
Anesth Analg 2005 101: 1873-1876. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: To determine the efficacy of salivary biomarkers for assessing mental stress, we examined the relationship between State Anxiety Inventory score and salivary chromogranin-A, α-amylase, and cortisol during a mental arithmetic task. Because there was a significant correlation with α-amylase only, this marker may be a useful indicator of mental stress.

Edmond Cohen

The Cohen Flexitip Endobronchial Blocker: An Alternative to a Double Lumen Tube (Case Report)
Anesth Analg 2005 101: 1877-1879. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This case report describes the technical features and technical use of a new tip-deflecting endobronchial blocker that can be used during lung surgery to exclude the operative lung from the ventilation.

LETTER TO THE EDITOR:

Jeremy Scarlett, Nathan Hahn, Eric Jacobsohn, and Michael S. Avidan

The Evidence That Deep Anesthesia Impacts Long Term Mortality Is Not Compelling
Anesth Analg 2005 101: 1880. [Full Text] [PDF] [Request Permissions]  

Terri G. Monk, B. Craig Weldon, Vikas Saini, and Jeffrey C. Sigl

The Evidence That Deep Anesthesia Impacts Long Term Mortality Is Not Compelling
Anesth Analg 2005 101: 1880-1881. [Full Text] [PDF] [Request Permissions]  

Cuneyt Yilmazer, Mesut Sener, and Ismail Yilmaz

Bilateral Giant Posterior Laryngeal Granulomas with Dyspnea: A Rare Complication of Endotracheal Intubation
Anesth Analg 2005 101: 1881-1882. [Full Text] [PDF] [Request Permissions]  

Stefan A. Ianchulev

Through-the-LMA Fiberoptic Intubation of the Trachea in a Patient with an Unexpected Difficult Airway
Anesth Analg 2005 101: 1882-1883. [Full Text] [PDF] [Request Permissions]  

Zoher Naja, Ahed Zeidan, Hilal Maaliki, Samir Zoubeir, R. El-Khatib, and Anis Baraka

Tetraplegia After Coronary Artery Bypass Grafting in a Patient with Undiagnosed Cervical Stenosis
Anesth Analg 2005 101: 1883-1884. [Full Text] [PDF] [Request Permissions]  

Susumu Fujioka

Tetraplegia After Coronary Artery Bypass Grafting in a Patient with Undiagnosed Cervical Stenosis
Anesth Analg 2005 101: 1884. [Full Text] [PDF] [Request Permissions]  

Ashley Webb and Sam Leong

The Combination of Tramadol and Morphine May Be Recommended for Postoperative Analgesia
Anesth Analg 2005 101: 1884-1885. [Full Text] [PDF] [Request Permissions]  

Dan Benhamou, Jean-Xavier Mazoit, and Aurore Marcou

The Combination of Tramadol and Morphine May Be Recommended for Postoperative Analgesia
Anesth Analg 2005 101: 1885. [Full Text] [PDF] [Request Permissions]  

Petros Kopterides

What Is the Appropriate Anticoagulation Therapy in Patients with a History of Heparin-Induced Thrombocytopenia?
Anesth Analg 2005 101: 1885. [Full Text] [PDF] [Request Permissions]  

André P. Boezaart and Mace A. Nosovitch

Carotid Endarterectomy Using Single Injection Posterior Cervical Paravertebral Block
Anesth Analg 2005 101: 1885-1886. [Full Text] [PDF] [Request Permissions]  

Harald Hollnberger, Elisabeth Gruber, and Birgit Seelbach-Goebel

Major Post-Partum Hemorrhage and Treatment with Recombinant Factor VIIa
Anesth Analg 2005 101: 1886-1887. [Full Text] [PDF] [Request Permissions]  

Paul F. White

Treatment of Postoperative Nausea and Vomiting with Dolasetron Versus Ondansetron: Is There a Conflict of Interest?
Anesth Analg 2005 101: 1887. [Full Text] [PDF] [Request Permissions]  

Charles R. Roberson and Tricia A. Meyer

Treatment of Postoperative Nausea and Vomiting with Dolasetron Versus Ondansetron: Is There a Conflict of Interest?
Anesth Analg 2005 101: 1887-1888. [Full Text] [PDF] [Request Permissions]  

J. H. van Oostrom

Web-Based Data Collection: Security Is Only as Good as the Weakest Link
Anesth Analg 2005 101: 1888. [Full Text] [PDF] [Request Permissions]  

Alexander Avidan, Charles Weissman, and Charles L. Sprung

Web-Based Data Collection: Security Is Only as Good as the Weakest Link
Anesth Analg 2005 101: 1888. [Full Text] [PDF] [Request Permissions]  

Robert F. Atkins

The LMA Is a Critical Rescue Device in Airway Emergencies
Anesth Analg 2005 101: 1888-1889. [Full Text] [PDF] [Request Permissions]  

David T. Wong

The LMA Is a Critical Rescue Device in Airway Emergencies
Anesth Analg 2005 101: 1889. [Full Text] [PDF] [Request Permissions]  

Manuel Muñoz, Elvira Bisbe, José Antonio García-Erce, and Jorge Cuenca

Allogeneic Blood Transfusion and Wound Healing Disturbance After Orthopaedic Surgery
Anesth Analg 2005 101: 1889-1890. [Full Text] [PDF] [Request Permissions]  

Eric W. G. Weber, D. Strümper, and M. E. Durieux

Allogeneic Blood Transfusion and Wound Healing Disturbance After Orthopaedic Surgery
Anesth Analg 2005 101: 1890. [Full Text] [PDF] [Request Permissions]  

Babita Ghai and Jeetinder Kaur Makkar

An Unusual Cause of Faulty Tec 7 Vaporizer
Anesth Analg 2005 101: 1890-1891. [Full Text] [PDF] [Request Permissions]  

Masahiro Yagihara, Masayuki Miyabe, Taro Mizutani, Yukio Sato, and Hidenori Toyooka

Intraduodenal Milk Injection After Induction of General Anesthesia Is Safe and Useful During Surgical Treatment for Intractable Chylothorax
Anesth Analg 2005 101: 1891. [Full Text] [PDF] [Request Permissions]  

Rodrigo Diaz, Glauber Gouvêa, Lúcio Auler, and Rosalice Miecznikowski

Thoracic Epidural Anesthesia in Pediatric Liver Transplantation
Anesth Analg 2005 101: 1891-1892. [Full Text] [PDF] [Request Permissions]  

P. Saravanan and J. E. Arrowsmith

Retrograde Submental Intubation After Faciomaxillary Trauma
Anesth Analg 2005 101: 1892-1893. [Full Text] [PDF] [Request Permissions]  

Virendra K. Arya, Arun Kumar, Surinder S. Makkar, and Ramesh K. Sharma

Retrograde Submental Intubation After Faciomaxillary Trauma
Anesth Analg 2005 101: 1893-1894. [Full Text] [PDF] [Request Permissions]  

Rangraj Setlur and Ram M. Sharma

Severe Metabolic Acidosis Secondary to Organophosphate Poisoning
Anesth Analg 2005 101: 1894. [Full Text] [PDF] [Request Permissions]  

BOOK AND MULTIMEDIA REVIEWS:

Robert E. Johnstone

Anesthesia. 6th ed.
Anesth Analg 2005 101: 1895. [Full Text] [PDF] [Request Permissions]  

Frederic A. Berry

Legal and Ethical Aspects of Anaesthesia, Critical Care, and Perioperative Medicine.
Anesth Analg 2005 101: 1895-1896. [Full Text] [PDF] [Request Permissions]  

Dan R. Brown

Critical Care Medicine: Review and Self-Assessment.
Anesth Analg 2005 101: 1896-1897. [Full Text] [PDF] [Request Permissions]  

Books and Multimedia Received
Anesth Analg 2005 101: 1897. [Full Text] [PDF] [Request Permissions]  

ERRATA:

Erratum
Anesth Analg 2005 101: 1614. [Full Text] [PDF] [Request Permissions]  

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