The Use of Oral Granisetron Versus Intravenous Ondansetron for Antiemetic Prophylaxis in Patients Undergoing Laparoscopic Surgery: The Effect on Emetic Symptoms and Quality of Recovery
Anesth Analg 2006 102: 1387-1393.
[Abstract]
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IMPLICATIONS: Preoperative administration of granisetron, 1 mg per os, was not significantly different from ondansetron, 4 mg IV, in preventing emetic symptoms and improving recovery after laparoscopic surgery. However, ondansetron was more cost-effective than granisetron for routine prophylaxis as a result of its lower cost and comparable antiemetic efficacy and patient satisfaction.