ARTICLE:

GUEST REVIEWER LIST APRIL 1, 2007–SEPTEMBER 30, 2007
Anesth Analg 2007 104: E1-E5. [Full Text] [PDF] [Request Permissions]  

EDITORIALS:

Jeannie Wurz and Bruno Regli

In One Ear and Out the Other: Communication Barriers as a Risk Factor for Critical Incidents
Anesth Analg 2007 104: 1319-1321. [Full Text] [PDF] [Request Permissions]  

Manu Sethi and Charles D. Collard

Perioperative Statin Therapy: Are Formal Guidelines and Physician Education Needed?
Anesth Analg 2007 104: 1322-1324. [Full Text] [PDF] [Request Permissions]  

CARDIOVASCULAR ANESTHESIA:

Yannick Le Manach, Gilles Godet, Pierre Coriat, Claire Martinon, Michèle Bertrand, Marie-Hélène Fléron, and Bruno Riou

The Impact of Postoperative Discontinuation or Continuation of Chronic Statin Therapy on Cardiac Outcome After Major Vascular Surgery
Anesth Analg 2007 104: 1326-1333. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We retrospectively examined the frequency of cardiac myonecrosis (troponin I release >0.2 ng/mL) in patients who had either statin therapy discontinued or resumed immediately after major vascular surgery. Discontinuation of statin therapy was associated with an increased postoperative cardiac risk, suggesting that statin therapy should be resumed early after major vascular surgery.

Glenn S. Murphy, Joseph W. Szokol, Jesse H. Marymont, Michael J. Avram, and Jeffery S. Vender

The Effects of Morphine and Fentanyl on the Inflammatory Response to Cardiopulmonary Bypass in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery
Anesth Analg 2007 104: 1334-1342. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Experimental data suggest that morphine has unique antiinflammatory properties. In this randomized, double-blind, clinical trial, we observed that morphine attenuates the inflammatory response to cardiopulmonary bypass compared with a fentanyl-based balanced anesthetic technique.

Edel Duggan, Michael J. O’Dwyer, Emma Caraher, Dara Diviney, Eilis McGovern, Dermot Kelleher, Ross McManus, and Thomas Ryan

Coagulopathy After Cardiac Surgery May Be Influenced by a Functional Plasminogen Activator Inhibitor Polymorphism
Anesth Analg 2007 104: 1343-1347. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In this observational study of elective cardiac surgery patients we demonstrate a consistent decrease in plasminogen activator inhibitor-1 (PAI-1) mRNA production after cardiopulmonary bypass. The extent of the decrease was related to PAI-1 genotype. In addition, we describe an association between PAI-1 4G/5G genotype and a propensity to receive coagulation blood products early after cardiac surgery.

Leonid L. Minkovich, Stephanie J. Brister, and Peter D. Slinger

Transesophageal Echocardiography in Adult-Type Bland-White-Garland Syndrome (Echo Rounds)
Anesth Analg 2007 104: 1348-1349. [Full Text] [PDF] [Echo Loop]  [Request Permissions]  

Madhav Swaminathan, Hilary P. Grocott, G. Burkhard Mackensen, Mihai V. Podgoreanu, Donald D. Glower, and Joseph P. Mathew

The "Sandblasting" Effect of Aortic Cannula on Arch Atheroma During Cardiopulmonary Bypass (Echo Rounds)
Anesth Analg 2007 104: 1350-1351. [Full Text] [PDF] [Echo Loops]  [Request Permissions]  

PEDIATRIC ANESTHESIA:

Young-Chang P. Arai, Meiho Nakayama, Naoko Kato, Yoshiko Wakao, Hiroshi Ito, and Toru Komatsu

The Effects of Jaw Thrust and the Lateral Position on Heart Rate Variability in Anesthetized Children with Obstructive Sleep Apnea Syndrome
Anesth Analg 2007 104: 1352-1355. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In children with obstructive sleep apnea syndrome, in the neutral neck position, anesthesia induced an occluded airway and changed heart rate variability (HRV). Relief of the occluded airway by jaw thrust and lateral positioning returned HRV to preanesthetic levels. These changes in HRV paralleled the improved stridor scores.

Thomas R. Vetter, Daniel Carvallo, Jodie L. Johnson, Michael S. Mazurek, and Robert G. Presson, Jr

A Comparison of Single-Dose Caudal Clonidine, Morphine, or Hydromorphone Combined with Ropivacaine in Pediatric Patients Undergoing Ureteral Reimplantation
Anesth Analg 2007 104: 1356-1363. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study compares caudal clonidine, morphine, and hydromorphone in children undergoing ureteral reimplantation procedures and concludes that caudal clonidine provides comparable analgesia with fewer side effects.

Britta S. von Ungern-Sternberg, Adrian Regli, Andreas Schibler, Jürg Hammer, Franz J. Frei, and Thomas O. Erb

The Impact of Positive End-Expiratory Pressure on Functional Residual Capacity and Ventilation Homogeneity Impairment in Anesthetized Children Exposed to High Levels of Inspired Oxygen
Anesth Analg 2007 104: 1364-1368. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Functional residual capacity (FRC) and ventilation distribution decreased significantly at a fraction of inspired oxygen (Fio2) of 1.0 compared with an Fio2 of 0.3 when children were ventilated with a very low positive end-expiratory pressure (PEEP) of 3-cm H2O. These changes in FRC and ventilation distribution were prevented by the continuous administration of PEEP of 6-cm H2O.

AMBULATORY ANESTHESIA:

Keith A. Candiotti, Fani Nhuch, Aimee Kamat, Krisnaprasad Deepika, Kristopher L. Arheart, David J. Birnbach, and David A. Lubarsky

Granisetron Versus Ondansetron Treatment for Breakthrough Postoperative Nausea and Vomiting After Prophylactic Ondansetron Failure: A Pilot Study
Anesth Analg 2007 104: 1370-1373. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: No significant benefit was found in treating patients who failed ondansetron 4 mg prophylaxis with granisetron in doses of either 0.1 or 1 mg.

Martin R. Tramèr and Chris J. Glynn

An Evaluation of a Single Dose of Magnesium to Supplement Analgesia After Ambulatory Surgery: Randomized Controlled Trial
Anesth Analg 2007 104: 1374-1379. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In a randomized, placebo-controlled, double-blind trial, an IV bolus of magnesium sulfate 4 g, administered after anesthetic induction in patients undergoing ambulatory ilioinguinal hernia repair or varicose vein operations under general anesthesia, had no impact on postoperative pain and analgesic consumption.

Paul F. White, Henrik Kehlet, Joseph M. Neal, Thomas Schricker, Daniel B. Carr, Franco Carli, and the Fast-Track Surgery Study Group

The Role of the Anesthesiologist in Fast-Track Surgery: From Multimodal Analgesia to Perioperative Medical Care (Special Article)
Anesth Analg 2007 104: 1380-1396. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The pivotal role of the anesthesiologist as the key perioperative physician in facilitating the recovery process has assumed increased importance in the current fast-track recovery environment. The choice of premedication, anesthetic, analgesic and antiemetic drugs, as well as cardiovascular, hormonal, and fluid therapies, can influence the ability to fast-track patients after elective surgery.

ANESTHETIC PHARMACOLOGY:

Boris Singler, Andreas Tröster, Neil Manering, Jürgen Schüttler, and Wolfgang Koppert

Modulation of Remifentanil-Induced Postinfusion Hyperalgesia by Propofol
Anesth Analg 2007 104: 1397-1403. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Brief opioid exposure can enhance pain sensitivity. We investigated subhypnotic concentrations of propofol on remifentanil-induced hypersensitivity in an experimental human pain model. Propofol delayed and decreased, but did not completely antagonize, remifentanil-induced anti-analgesia. This may explain the increased demand for analgesics after remifentanil-based anesthesia.

Jong Woo Chung, Joong Ho Ahn, Jong Yang Kim, Hyun Jung Lee, Hun Hee Kang, Yoon Kyung Lee, Joung Uk Kim, and Seung-Woo Koo

The Effect of Isoflurane, Halothane and Pentobarbital on Noise-Induced Hearing Loss in Mice
Anesth Analg 2007 104: 1404-1408. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Halothane, isoflurane, and pentobarbital protected mice against noise-induced hearing loss and hair cell damage and inhaled anesthetics were more effective than pentobarbital.

Åsa Rudin, Johan F. Lundberg, Margareta Hammarlund-Udenaes, Per Flisberg, and Mads U. Werner

Morphine Metabolism After Major Liver Surgery
Anesth Analg 2007 104: 1409-1414. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study demonstrates that patients undergoing major liver surgery have a decreased morphine clearance. The impaired morphine metabolism is associated with an increased incidence of sedation.

Masahiro Irifune, Nobuhito Kikuchi, Takuya Saida, Tohru Takarada, Yoshitaka Shimizu, Chie Endo, Katsuya Morita, Toshihiro Dohi, Tomoaki Sato, and Michio Kawahara

Riluzole, a Glutamate Release Inhibitor, Induces Loss of Righting Reflex, Antinociception, and Immobility in Response to Noxious Stimulation in Mice
Anesth Analg 2007 104: 1415-1421. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Glutamatergic neurons are important targets for anesthetic action. We examined the ability of riluzole, which inhibits glutamate release from nerve terminals, to produce components of the anesthetic state. Our findings suggest that riluzole-induced loss of consciousness, immobility, and antinociception are associated with inhibition of glutamatergic neurotransmission in the central nervous system.

Sohtaro Katayama, Masahiro Irifune, Nobuhito Kikuchi, Tohru Takarada, Yoshitaka Shimizu, Chie Endo, Takashi Takata, Toshihiro Dohi, Tomoaki Sato, and Michio Kawahara

Increased -Aminobutyric Acid Levels in Mouse Brain Induce Loss of Righting Reflex, but Not Immobility, in Response to Noxious Stimulation
Anesth Analg 2007 104: 1422-1429. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The functional relevance of {gamma}-aminobutyric acid (GABA)-ergic inhibitory neurotransmission in mediating essential components of anesthesia is unknown. We examined the ability of increased GABA levels to produce behavioral components of anesthesia. Our findings suggest that unconsciousness and immobility are mediated through different neuronal pathways and/or regions in the central nervous system.

Robert J. Brosnan, Liya Yang, Pavle S. Milutinovic, Jing Zhao, Michael J. Laster, Edmond I. Eger, II, and James M. Sonner

Ammonia Has Anesthetic Properties
Anesth Analg 2007 104: 1430-1433. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Ammonia is a metabolite with anesthetic-like effects on both anesthetic-sensitive ion channels and in whole animals.

Koji Hara and Takeyoshi Sata

The Effects of the Local Anesthetics Lidocaine and Procaine on Glycine and -Aminobutyric Acid Receptors Expressed in Xenopus Oocytes
Anesth Analg 2007 104: 1434-1439. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Lidocaine and procaine enhanced glycine receptor function at low concentrations and inhibited glycine and {gamma}-aminobutyric acid type A receptors functions at high concentrations. The mechanism of the local anesthetic (LA)-induced enhancement of glycine receptor function probably differs from that of general anesthetics. These findings may explain the pharmacological effects of LAs, such as antinociception and convulsion.

Logan J. Voss, Guy Ludbrook, Cliff Grant, Richard Upton, and James W. Sleigh

A Comparison of Pharmacokinetic/Pharmacodynamic versus Mass-Balance Measurement of Brain Concentrations of Intravenous Anesthetics in Sheep
Anesth Analg 2007 104: 1440-1446. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Accurate estimates of t1/2Keo are critical for effect-compartment dosing in IV anesthesia. We compared the pharmacokinetic/pharmacodynamic and mass-balance methods for propofol, methohexital, and ketamine in a sheep model. Both methods give similar values for t1/2Keo. Methohexital crosses into the brain much faster than either propofol or ketamine.

Max T. Baker

Sevoflurane: Are There Differences in Products? (Medical Intelligence)
Anesth Analg 2007 104: 1447-1451. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Although the two sevoflurane products available in the United States are rated therapeutically equivalent, there are differences in the manufacturing processes between Ultane(R) and generic sevoflurane. They are also packaged in different containers. The quantities of impurities are, however, low and qualitative differences minor and unlikely to be of clinical significance.

James S. Anderson, Noel R. Rose, Jackie L. Martin, Edmond I. Eger, and Dolores B. Njoku

Desflurane Hepatitis Associated with Hapten and Autoantigen-Specific IgG4 Antibodies (Case Report)
Anesth Analg 2007 104: 1452-1453. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We provide the first documentation of cytochrome P450 2E1 IgG4 autoantibodies, as well as 58 kDa endoplasmic reticulum protein and trifluoroacetyl chloride hapten-specific IgG4 antibodies, in a patient who developed hepatitis after desflurane anesthesia. These findings suggest that allergic and autoimmune mechanisms have critical roles in the development of desflurane-induced liver injury.

TECHNOLOGY, COMPUTING, AND SIMULATION:

William D. Driscoll, Mary Ann Columbia, and Robert A. Peterfreund

An Observational Study of Anesthesia Record Completeness Using an Anesthesia Information Management System
Anesth Analg 2007 104: 1454-1461. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Evaluation of records created using an anesthesia information system indicates that documentation is often incomplete. Further study is necessary to understand the relationship between the system design and completeness of documentation.

David B. Wax, Yaakov Beilin, Matthew Levin, Neil Chadha, Marina Krol, and David L. Reich

The Effect of an Interactive Visual Reminder in an Anesthesia Information Management System on Timeliness of Prophylactic Antibiotic Administration
Anesth Analg 2007 104: 1462-1466. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Timely administration of prophylactic antibiotics can be improved by adding a visual reminder to the display of an anesthesia information system.

ECONOMICS, EDUCATION, AND POLICY:

Getúlio R. de Oliveira Filho and Joaquim Edson Vieira

The Relationship of Learning Environment, Quality of Life, and Study Strategies Measures to Anesthesiology Resident Academic Performance
Anesth Analg 2007 104: 1467-1472. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Differences in academic performance among anesthesia residents were not due to differences in rate of learning, but baseline differences in affective-motivational variables: level of anxiety related to study and achievement, motivation for learning and for personal improvement, and ability to select main ideas from subject matters to which residents are exposed during learning episodes.

CRITICAL CARE AND TRAUMA:

Henry R. Kroll and Thomas R. Maher

Significant Hypoglycemia Secondary to Icodextrin Peritoneal Dialysate in a Diabetic Patient (Case Report)
Anesth Analg 2007 104: 1473-1474. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Icodextrin, a peritoneal dialysate commonly used in the renal failure patient with diabetes, may lead to an overestimation of blood glucose levels as determined by bedside glucometers. Failure to communicate this information to all caregivers may lead to inappropriate treatment and patient mortality.

Thomas G. Ruttmann, Luis F. Montoya-Pelaez, and Michael F. M. James

The Coagulation Changes Induced by Rapid In Vivo Crystalloid Infusion Are Attenuated When Magnesium Is Kept at the Upper Limit of Normal
Anesth Analg 2007 104: 1475-1480. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Large volume crystalloid resuscitation may enhance coagulation. This procoagulant effect may be attenuated by magnesium.

NEUROSURGICAL ANESTHESIA:

Uwe Schulz, Didier Keh, Christoph Barner, Udo Kaisers, and Willehad Boemke

Bispectral Index Monitoring Does Not Improve Anesthesia Performance in Patients with Movement Disorders Undergoing Deep Brain Stimulating Electrode Implantation
Anesth Analg 2007 104: 1481-1487. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Bispectral Index did not reduce propofol consumption or speed arousal times in patients with movement disorders undergoing deep brain stimulation.

Yuri Yamamoto, Masahiko Kawaguchi, Meiko Kakimoto, Satoki Inoue, and Hitoshi Furuya

The Effects of Dexmedetomidine on Myogenic Motor Evoked Potentials in Rabbits
Anesth Analg 2007 104: 1488-1492. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In rabbits, dexmedetomidine produces a dose-dependent suppression of motor evoked potentials (MEPs). Use of multipulses allowed MEPs to be recorded at 50 {micro}g/kg/h of dexmedetomidine

Guruswamy Balakrishnan, Kavita M. Grover, Karen Mason, Brien Smith, Gregory L. Barkley, Norman Tepley, and Susan M. Bowyer

A Retrospective Analysis of the Effect of General Anesthetics on the Successful Detection of Interictal Epileptiform Activity in Magnetoencephalography
Anesth Analg 2007 104: 1493-1497. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This retrospective study demonstrates that the levels of anesthesia needed to provide unconsciousness and immobility during magnetoencephalography(MEG) studies do not significantly alter the likelihood of recording interictal epileptiform spike activity with MEG.

Mei Wang and Shailendra Joshi

Electrocerebral Silence After Intracarotid Propofol Injection Is a Function of Transit Time
Anesth Analg 2007 104: 1498-1503. [Abstract] [Full Text] [PDF] [Videos]  [Request Permissions]  

IMPLICATIONS: The duration of electrocerebral silence after intracarotid bolus injection of propofol during cerebral hypoperfusion was related to the transit time of the propofol emulsion. In the cerebral circulation, the effects of highly lipid-soluble drugs are a function of the time available for the drug to diffuse across the blood brain barrier.

PAIN MEDICINE:

Jeffrey W. Allen, Katrin Hofer, Damon McCumber, John D. Wagstaff, Richard T. Layer, R. Tyler McCabe, and Tony L. Yaksh

An Assessment of the Antinociceptive Efficacy of Intrathecal and Epidural Contulakin-G in Rats and Dogs
Anesth Analg 2007 104: 1505-1513. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Using rat and dog models of nociception, we have demonstrated contulakin-G to be highly effective, with minimal side effects, when delivered as an intrathecal bolus.

Steven E. Kern, Jeff Allen, John Wagstaff, Steven L. Shafer, and Tony Yaksh

The Pharmacokinetics of the Conopeptide Contulakin-G (CGX-1160) After Intrathecal Administration: An Analysis of Data from Studies in Beagles
Anesth Analg 2007 104: 1514-1520. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study determined the time course that a dose of CGX-1160 lasts after spinal administration into beagle dogs. This agent is a man-made derivative from a peptide toxin naturally found in marine snails that has been shown to possess analgesic activity.

Valéria Martinez, Anissa Belbachir, Aithem Jaber, Kamel Cherif, Adel Jamal, Yves Ozier, Daniel I. Sessler, Marcel Chauvin, and Dominique Fletcher

The Influence of Timing of Administration on the Analgesic Efficacy of Parecoxib in Orthopedic Surgery
Anesth Analg 2007 104: 1521-1527. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Preoperative parecoxib does not provide clinically significant preemptive analgesia. However, perioperative parecoxib provides substantial postoperative analgesia after total hip arthroplasty for the first 24 h after surgery without increasing perioperative bleeding.

Michelle Franz-Montan, André L. R. Silva, Karina Cogo, Cristiane de C. Bergamaschi, Maria C. Volpato, José Ranali, Eneida de Paula, and Francisco C. Groppo

Liposome-Encapsulated Ropivacaine for Topical Anesthesia of Human Oral Mucosa
Anesth Analg 2007 104: 1528-1531. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Liposome encapsulation enhanced the anesthetic properties of ropivacaine, which was comparable with EMLA in reducing pain and discomfort during needle insertion into the oral mucosa.

Christopher Lysakowski, Lionel Dumont, Christoph Czarnetzki, and Martin R. Tramèr

Magnesium as an Adjuvant to Postoperative Analgesia: A Systematic Review of Randomized Trials
Anesth Analg 2007 104: 1532-1539. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Systematically searched randomized trials do not provide convincing evidence that perioperative magnesium may have favorable effects on postoperative pain intensity and analgesic requirements. Perioperative magnesium supplementation prevents postoperative hypomagnesemia and decreases the incidence of postoperative shivering.

Marie T. Aouad, Sahar M. Siddik-Sayyid, Achir A. Al-Alami, and Anis S. Baraka

Multimodal Analgesia to Prevent Propofol-Induced Pain: Pretreatment with Remifentanil and Lidocaine Versus Remifentanil or Lidocaine Alone
Anesth Analg 2007 104: 1540-1544. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This prospective, randomized, double-blind study evaluated the incidence and severity of propofol injection pain after pretreatment with remifentanil, premixing propofol with lidocaine, or the combination of both. The combination of remifentanil and lidocaine significantly reduced the incidence of mild pain and completely abolished moderate and severe pain as compared to either drug alone.

Elina M. Tiippana, Katri Hamunen, Vesa K. Kontinen, and Eija Kalso

Do Surgical Patients Benefit from Perioperative Gabapentin/Pregabalin? A Systematic Review of Efficacy and Safety
Anesth Analg 2007 104: 1545-1556. [Abstract] [Full Text] [PDF] [Data Supplement]  [Request Permissions]  

IMPLICATIONS: This systematic review shows that preoperative administration of gabapentin/pregabalin reduces postoperative pain intensity, opioid consumption, and opioid-related adverse effects without major risks. Studies defining optimal dosing, duration of the treatment, and effects on chronic pain are needed.

Michael H. Verdolin, Eric T. Stedje-Larsen, and Anita H. Hickey

Ten Consecutive Cases of Complex Regional Pain Syndrome of Less than 12 Months Duration in Active Duty United States Military Personnel Treated with Spinal Cord Stimulation (Case Report)
Anesth Analg 2007 104: 1557-1560. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Spinal cord stimulation for refractory complex regional pain syndrome of less than 1 yr duration may be effective as measured by decreased opioid intake, participation with physical rehabilitation, and retention on active military duty. These observations should be interpreted cautiously based on the short duration of postimplantation follow-up and the small number of cases presented.

Carlos R. D. Oliveira, Fúlvio A. dos Santos, Celso S. Nogueira, and Emerson J. Mainardes

Spinal Anesthesia in a Patient with Congenital Insensitivity to Pain with Anhidrosis (Case Report)
Anesth Analg 2007 104: 1561-1562. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The authors used spinal anesthesia in a patient with congenital insensitivity to pain with anhidrosis for surgery on both knees without complications. Spinal anesthesia may be a useful alternative to general anesthesia in such patients if they are cooperative.

PAIN MECHANISMS:

Josée Guindon, Jesse LoVerme, Daniele Piomelli, and Pierre Beaulieu

The Antinociceptive Effects of Local Injections of Propofol in Rats Are Mediated in Part by Cannabinoid CB₁ and CB₂ Receptors
Anesth Analg 2007 104: 1563-1569. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Propofol may interact with peripheral cannabinoid receptors to alter facilitated pain states initiated by local inflammation.

Takahiro Suzuki, Mitsuyuki Amata, Gaku Sakaue, Shinya Nishimura, Takaya Inoue, Masahiko Shibata, and Takashi Mashimo

Experimental Neuropathy in Mice Is Associated with Delayed Behavioral Changes Related to Anxiety and Depression
Anesth Analg 2007 104: 1570-1577. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Patients with chronic pain frequently suffer affective disorders. To study the relationship between pain and affective disorders, we examined anxiety and depression-related behaviors in mice subjected to spinal nerve ligation. Nerve injury can trigger affective disturbances in mice that appear much later than sensory hypersensitivity.

REGIONAL ANESTHESIA:

Martin Wiegel, Udo Gottschaldt, Ria Hennebach, Thilo Hirschberg, and Andreas Reske

Complications and Adverse Effects Associated with Continuous Peripheral Nerve Blocks in Orthopedic Patients
Anesth Analg 2007 104: 1578-1582. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In this prospective observational study involving 1398 continuous peripheral nerve catheters, serious complications, such as permanent nerve damage, and major bleeding, were rare. However, minor complications, including vascular puncture and local inflammation, were more common.

Chul Joong Lee, Yunseok Jeon, Young Jin Lim, Jae Hyon Bahk, Yong Chul Kim, Sang Chul Lee, and Chong Sung Kim

The Influence of Neck Flexion and Extension on the Distribution of Contrast Medium in the High Thoracic Epidural Space
Anesth Analg 2007 104: 1583-1586. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: During high (T1 2) epidural analgesia, the tip of the epidural catheter should be at the upper margin of the level to be blocked and neck flexion may cause an unwanted cervical block.

Francesco Donatelli, Angelo Vavassori, Simona Bonfanti, Piervirgilio Parrella, Luca Lorini, Roberto Fumagalli, and Franco Carli

Epidural Anesthesia and Analgesia Decrease the Postoperative Incidence of Insulin Resistance in Preoperative Insulin-Resistant Subjects Only
Anesth Analg 2007 104: 1587-1593. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Insulin resistance is a feature of the endocrine stress response to surgery. In this study, epidural anesthesia and analgesia, compared with general anesthesia and patient-controlled analgesia, decreased the incidence of insulin resistance immediately after surgery and 48 h postoperatively in patients who were insulin-resistant before surgery.

Medhat R. Wassef, Emil I. Michaels, Jeffrey M. Rangel, and Arkadiy T. Tsyrlin

Spinal Perianal Block: A Prospective, Randomized, Double-Blind Comparison with Spinal Saddle Block (Brief Report)
Anesth Analg 2007 104: 1594-1596. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In patients undergoing short perianal procedures, very low dose bupivacaine spinal block led to earlier readiness to home discharge, was without side effects, and was associated with a high degree of patient satisfaction.

LETTERS TO THE EDITOR:

Mark Rothmann, M. Miles Braun, and Tie-Hua Ng

On the Hazard Ratios and Corresponding Confidence Intervals That Appear in Basran et al. (2006)
Anesth Analg 2007 104: 1597. [Full Text] [PDF] [Request Permissions]  

Sukhjeewan Basran, Robert J. Frumento, Allison Cohen, Samuel Lee, Yuling Du, Ervant Nishanian, Harold S. Kaplan, Mark Stafford-Smith, and Elliott Bennett-Guerrero

On the Hazard Ratios and Corresponding Confidence Intervals That Appear in Basran et al. (2006)
Anesth Analg 2007 104: 1597. [Full Text] [PDF] [Request Permissions]  

Steven L. Shafer

Occam’s Razor
Anesth Analg 2007 104: 1597-1598. [Full Text] [PDF] [Data Supplement]  [Request Permissions]  

Maxime Cannesson, Olivier Desebbe, and Jean-Jacques Lehot

Fluid Responsiveness Assessment Using the Pulse Oxymeter Waveform: Not Yet Ready for Prime Time
Anesth Analg 2007 104: 1598-1599. [Full Text] [PDF] [Request Permissions]  

Benoît Tavernier, Marie-Sophie Destandau, and Benoît Vallet

Variations in Photoplethysmographic Waveform During Mechanical Ventilation
Anesth Analg 2007 104: 1599. [Full Text] [PDF] [Request Permissions]  

Giuseppe Natalini

Variations in Photoplethysmographic Waveform During Mechanical Ventilation
Anesth Analg 2007 104: 1599-1600. [Full Text] [PDF] [Request Permissions]  

Robert J. Coffey and Jeffrey W. Allen

Not All Intrathecal Catheter Tip MRI Findings Are Inflammatory Masses
Anesth Analg 2007 104: 1600-1602. [Full Text] [PDF] [Request Permissions]  

Paul M. Murphy and Michael J. Cousins

Not All Intrathecal Catheter Tip MRI Findings Are Inflammatory Masses
Anesth Analg 2007 104: 1602. [Full Text] [PDF] [Request Permissions]  

Paul M. Kempen

Let Us Make MRI Anesthesia Safe!
Anesth Analg 2007 104: 1602. [Full Text] [PDF] [Request Permissions]  

Randall Wetzel

Let Us Make MRI Anesthesia Safe!
Anesth Analg 2007 104: 1602. [Full Text] [PDF] [Request Permissions]  

Jochen Renner, Jens Scholz, and Berthold Bein

Dynamic Variables of Fluid Responsiveness may be Related to the Type of Volume Challenge Performed
Anesth Analg 2007 104: 1603. [Full Text] [PDF] [Request Permissions]  

Cyril Charron, Christine Fessenmeyer, Claudine Cosson, Jean-Louis Hebert, Dan Benhamou, Jean Xavier Mazoit, and Alain Edouard

Dynamic Variables of Fluid Responsiveness may be Related to the Type of Volume Challenge Performed
Anesth Analg 2007 104: 1603. [Full Text] [PDF] [Request Permissions]  

Prabhat Kumar Sinha and Thomas Koshy

Defective Double Lumen Tubes: Mallinckrodt the Culprit!
Anesth Analg 2007 104: 1603-1604. [Full Text] [PDF] [Request Permissions]  

Michael Vannier

Defective Double Lumen Tubes: Mallinckrodt the Culprit!
Anesth Analg 2007 104: 1604. [Full Text] [PDF] [Request Permissions]  

Yatindra K. Batra and Subramanyam Rajeev

Tribulations With Filling Tec 7 Vaporizers
Anesth Analg 2007 104: 1604. [Full Text] [PDF] [Request Permissions]  

Michael Mitton

Tribulations With Filling Tec 7 Vaporizers
Anesth Analg 2007 104: 1604-1605. [Full Text] [PDF] [Request Permissions]  

Dennis E. Feierman, Giuseppe Trunfio, Anand Morankar, and Evan Kharasch

More than Polymorphism
Anesth Analg 2007 104: 1605. [Full Text] [PDF] [Request Permissions]  

Piotr K. Janicki

More than Polymorphism
Anesth Analg 2007 104: 1605-1606. [Full Text] [PDF] [Request Permissions]  

Frédéric Michard

Using Pulse Oximetry Waveform Analysis to Guide Fluid Therapy: Are We There Yet?
Anesth Analg 2007 104: 1606-1607. [Full Text] [PDF] [Request Permissions]  

Kirk H. Shelley, Denis H. Jablonka, Aymen A. Awad, Robert G. Stout, Hoda Rezkanna, and David G. Silverman

Using Pulse Oximetry Waveform Analysis to Guide Fluid Therapy: Are We There Yet?
Anesth Analg 2007 104: 1607-1609. [Full Text] [PDF] [Request Permissions]  

Hector J. Lacassie, Hector P. Lacassie, and Malachy O. Columb

Reflections on Motor Blocking Minimum Local Anesthetic Concentrations
Anesth Analg 2007 104: 1609. [Full Text] [PDF] [Request Permissions]  

Yuhong Li

Reflections on Motor Blocking Minimum Local Anesthetic Concentrations
Anesth Analg 2007 104: 1609. [Full Text] [PDF] [Request Permissions]  

Wei-Ti Hsu, Shu-Chia Hsu, Yung-Lung Lee, Jinn-Sheng Huang, and Chao-Liang Chen

Penetrating Injury of the Soft Palate During GlideScope® Intubation
Anesth Analg 2007 104: 1609-1610. [Full Text] [PDF] [Request Permissions]  

Asif M. Malik and Jonathan K. Frogel

Anterior Tonsillar Pillar Perforation During Glidescope® Video Laryngoscopy
Anesth Analg 2007 104: 1610-1611. [Full Text] [PDF] [Request Permissions]  

John Allen Pacey

Anterior Tonsillar Pillar Perforation During Glidescope® Video Laryngoscopy
Anesth Analg 2007 104: 1611. [Full Text] [PDF] [Request Permissions]  

Thierry Girard and Albert Urwyler

Not Every Hypermetabolic State Is Due to Malignant Hyperthermia!
Anesth Analg 2007 104: 1611-1612. [Full Text] [PDF] [Request Permissions]  

Adam D. Lichtman and Charles Oribabor

If It Quacks Like a Duck Then ...!
Anesth Analg 2007 104: 1612-1613. [Full Text] [PDF] [Request Permissions]  

Paul M. Kempen

Weakness Following an Overdose of Lidocaine During General Anesthesia
Anesth Analg 2007 104: 1613. [Full Text] [PDF] [Request Permissions]  

Peter Szmuk, Alan Farrow-Gillespie, Paul Sheeran, and Tiberiu Ezri

The Sedative Effect of High Dose Lidocaine
Anesth Analg 2007 104: 1613. [Full Text] [PDF] [Request Permissions]  

Cheryl M. Gaughen and Marcel E. Durieux

The Sedative Effect of High Dose Lidocaine
Anesth Analg 2007 104: 1613-1614. [Full Text] [PDF] [Request Permissions]  

Muhammad Farooq

Can Electrocardiogram-Controlled Central Line Placement Decrease the Need for Routine Chest Radiographs After Central Venous Cannulation?
Anesth Analg 2007 104: 1614. [Full Text] [PDF] [Request Permissions]  

Ralf E. Gebhard

Can Electrocardiogram-Controlled Central Line Placement Decrease the Need for Routine Chest Radiographs After Central Venous Cannulation?
Anesth Analg 2007 104: 1614-1615. [Full Text] [PDF] [Request Permissions]  

John G. Brock-Utne

Be Aware of the Patient with an Eye Patch
Anesth Analg 2007 104: 1615. [Full Text] [PDF] [Request Permissions]  

Jonathan V. Roth

How to Enter a Medication Vial Without Coring
Anesth Analg 2007 104: 1615. [Full Text] [PDF] [Request Permissions]  

Jaclyn M. LeBlanc, Sandra L. Kane-Gill, Charles H. Cook, and Joseph F. Dasta

Bispectral Index Does Not Correlate with the Stress Response in Critical Care Patients
Anesth Analg 2007 104: 1616. [Full Text] [PDF] [Request Permissions]  

Jesse Aron and Debnath Chatterjee

Transient Pourfour du Petit Syndrome
Anesth Analg 2007 104: 1616. [Full Text] [PDF] [Request Permissions]  

Joel Waring, Sohail K. Mahboobi, Kalpana Tyagaraj, and David Eddi

Use of Remifentanil for Labor Analgesia: The Good and the Bad
Anesth Analg 2007 104: 1616-1617. [Full Text] [PDF] [Request Permissions]  

Nathalie Van Cutsem, Anne Ducart, and Arlette Vandesteene

A New Device for Regulation of Lumbar Cerebrospinal Fluid Drainage
Anesth Analg 2007 104: 1617-1618. [Full Text] [PDF] [Request Permissions]  

BOOK AND MULTIMEDIA REVIEWS:

Richard B. Patt

The 5-Minute Pain Management Consult
Anesth Analg 2007 104: 1619-1620. [Full Text] [PDF] [Request Permissions]  

Rafael Ortega

How to Survive in Anaesthesia: A Guide for Trainees, 3rd ed.
Anesth Analg 2007 104: 1620. [Full Text] [PDF] [Request Permissions]  

Doris Cope

Fast Facts: Chronic Pain
Anesth Analg 2007 104: 1620. [Full Text] [PDF] [Request Permissions]  

Elizabeth Kroepfl and Johanna Wallisa

Clinical Anesthesia Procedures of the Massachusetts General Hospital, 7th ed.
Anesth Analg 2007 104: 1620-1621. [Full Text] [PDF] [Request Permissions]  

ERRATA:

ERRATUM
Anesth Analg 2007 104: 1503. [Full Text] [PDF] [Request Permissions]  

ERRATUM
Anesth Analg 2007 104: 1544. [Full Text] [PDF] [Request Permissions]  

ERRATUM
Anesth Analg 2007 104: 1562. [Full Text] [PDF] [Request Permissions]  

ERRATUM
Anesth Analg 2007 104: 1577. [Full Text] [PDF] [Request Permissions]  

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