IMPLICATIONS: The development of pulse oximetry by Takuo Aoyagi is arguably the greatest advance inpatient safety in the history of Anesthesiology. The story of Aoyagi's discovery and that of earlier oximeter concepts is covered in this historical review.
IMPLICATIONS: The PPG, or the pulse waveform, measured with pulse oximetry is gaining increased attention as a source of useful physiological data, including vascular volume status, sympathetic tone and other variables. Maximizing the potential of this waveform requires standards for its display and experimentation investigating its clinical importance.
IMPLICATIONS: Darkly pigmented skin increases the bias in pulse oximeter measurements of oxyhemoglobin saturations at values <80%.
IMPLICATIONS: Hemoximetry on arterial blood is the reference standard for pulse oximeter accuracy testing. Hemoximeter accuracy varies with manufacturer, saturation range, and the species of hemoglobin in the sample.
Implications: We developed a comprehensive mathematical theory of pulse oximetry based on light scattering through complex tissues. The model predicts, and experiments show that using three- and five-wavelengths of light improves oximeter accuracy and reduces errors due to interfering factors.
IMPLICATIONS: A clinically relevant protocol for evaluating pulse oximeter errors because of patient motion has been lacking. We propose that training test subjects to create motions achieving standardized disturbances in pulse oximeter light signals can be used to objectively compare the motion resistance of oximeter probes and for the development of more motion-resistant oximeter designs.
IMPLICATIONS: Emerging technologies in sensors and microsystem integration are leading to miniaturized chip-scale integrated sensor systems for health monitoring that are more portable and wearable than current systems.
IMPLICATIONS: Safe and effective medical equipment design requires multidisciplinary contributions at all stages of the product lifecycle. Regulators and standards writers blend the concerns of engineers and clinicians to produce devices of optimal utility and safety.
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