EDITORIALS:

Pamela Flood

A New Treatment for Hypoxic Brain Injury?
Anesth Analg 2007 105: 559-560. [Full Text] [PDF]  

CARDIOVASCULAR ANESTHESIA:

Paul S. Pagel, John G. Krolikowski, Yon Hee Shim, Suneetha Venkatapuram, Judy R. Kersten, Dorothee Weihrauch, David C. Warltier, and Phillip F. Pratt, Jr

Noble Gases Without Anesthetic Properties Protect Myocardium Against Infarction by Activating Prosurvival Signaling Kinases and Inhibiting Mitochondrial Permeability Transition In Vivo
Anesth Analg 2007 105: 562-569. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Noble gases without anesthetic properties, including helium, neon, and argon, protect myocardium against infarction produced by prolonged coronary artery occlusion and reperfusion by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo.

Jerrold H. Levy, Kenichi A. Tanaka, and Marcie J. Hursting

Reducing Thrombotic Complications in the Perioperative Setting: An Update on Heparin-Induced Thrombocytopenia (Review Article)
Anesth Analg 2007 105: 570-582. [Abstract] [Full Text] [PDF] [CME]  

Siriluk Chumnanvej, Malissa J. Wood, Thomas E. MacGillivray, and Marcos F. Vidal Melo

Perioperative Echocardiographic Examination for Ventricular Assist Device Implantation (Review Article)
Anesth Analg 2007 105: 583-601. [Abstract] [Full Text] [PDF] [Video Clips]   

Mikhail R. Sukernik and Elliott Bennett-Guerrero

The Incidental Finding of a Patent Foramen Ovale During Cardiac Surgery: Should It Always Be Repaired? A Core Review (Review Article)
Anesth Analg 2007 105: 602-610. [Abstract] [Full Text] [PDF] [CME] [Video Clips]   

IMPLICATIONS: The incidental diagnosis of patent foramen ovale is often encountered on echocardiographic examination during cardiac surgery. We review the embryology, physiology, and proper methods for detection along with perioperative implications and decision-making processes that may lead to immediate, delayed, or no intervention.

Michael Argenziano

PRO: The Incidental Finding of a Patent Foramen Ovale During Cardiac Surgery: Should It Always Be Repaired? (Editorial)
Anesth Analg 2007 105: 611-612. [Full Text] [PDF]  

Frank A. Flachskampf

CON: The Incidental Finding of a Patent Foramen Ovale During Cardiac Surgery: Should It Always Be Repaired? (Editorial)
Anesth Analg 2007 105: 613-614. [Full Text] [PDF]  

PEDIATRIC ANESTHESIOLOGY:

Thomas Engelhardt, Man K. Chan, Alan J. McCheyne, Cengiz Karsli, Igor Luginbuehl, and Bruno Bissonnette

The Effect of Varying Continuous Propofol Infusions on Plasma Cyclic Guanosine 3',5'-Monophosphate Concentrations in Anesthetized Children
Anesth Analg 2007 105: 616-619. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Plasma cGMP concentrations are inversely correlated to measured plasma propofol concentrations in children. Plasma cGMP could serve as a biochemical marker for monitoring the depth of propofol anesthesia.

Seung-Yeon Yoo, Jin-Hee Kim, Sung-Hee Han, and Ah-Young Oh

A Comparative Study of Endotracheal Tube Positioning Methods in Children: Safety from Neck Movement
Anesth Analg 2007 105: 620-625. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We evaluated three clinically prevalent methods for endotracheal tube (ETT) positioning in children with regard to the safety from endobronchial intubation or extubation during neck movement. The results of our study suggest that ETT positioning by auscultation places the ETT more deeply than midtrachea, and therefore increases the risk of endobronchial intubation during neck flexion.

Yusuke Nagamine and Kiyoyasu Kurahashi

The Use of Three-Dimensional Computed Tomography Images for Anticipated Difficult Intubation Airway Evaluation of a Patient with Treacher Collins Syndrome (Case Report)
Anesth Analg 2007 105: 626-628. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This case report introduces the use of preanesthetic anatomical evaluation of the upper airway using three-dimensional computed tomography images for safe airway management of a patient predicted to be difficult to intubate.

ANESTHETIC PHARMACOLOGY:

Eliana Lucchinetti, José Aguirre, Jianhua Feng, Min Zhu, Marc Suter, Donat R. Spahn, Luc Härter, and Michael Zaugg

Molecular Evidence of Late Preconditioning After Sevoflurane Inhalation in Healthy Volunteers
Anesth Analg 2007 105: 629-640. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The authors demonstrate that a short period of sevoflurane inhalation at subanesthetic concentrations (<1%) alters the blood transcriptome in healthy volunteers. Flow cytometry analysis further demonstrated reduced L-selectin expression on granulocytes accompanied with resistance to inflammatory stimulation 24 to 48 h after sevoflurane exposure, consistent with the occurrence of a second window of protection in humans.

Sebastian N. Stehr, Torsten Christ, Berit Rasche, Stefan Rasche, Erich Wettwer, Andreas Deussen, Ursula Ravens, Thea Koch, and Matthias Hübler

The Effects of Levosimendan on Myocardial Function in Ropivacaine Toxicity in Isolated Guinea Pig Heart Preparations
Anesth Analg 2007 105: 641-647. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The calcium-sensitizer, levosimendan, is an effective inotropic drug in ropivacaine-induced myocardial depression. Levosimendan myocardial sensitivity and efficacy were not affected by the local anesthetic. Our results suggest that levosimendan is effective in local anesthetic-induced cardiac depression.

Ramachandran Ramani, Maolin Qiu, and Robert Todd Constable

Sevoflurane 0.25 MAC Preferentially Affects Higher Order Association Areas: A Functional Magnetic Resonance Imaging Study in Volunteers
Anesth Analg 2007 105: 648-655. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We used functional magnetic resonance imaging to measure the effects of 0.25 MAC sevoflurane on visual, auditory, and motor activation in 16 healthy volunteers. We showed that 0.25 MAC sevoflurane predominantly affects the primary visual cortex, the related association cortex, and certain other higher order association cortices.

Tadayoshi Kurita, Kotaro Takata, Masahiro Uraoka, Koji Morita, and Shigehito Sato

Landiolol, an Ultra–Short-Acting ß1-Adrenoceptor Antagonist, Does Not Alter the Minimum Alveolar Anesthetic Concentration of Isoflurane in a Swine Model
Anesth Analg 2007 105: 656-660. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We previously reported that landiolol, an ultra short-acting {beta}1-adrenoceptor antagonist, does not alter the electroencephalographic effect of isoflurane. Here, we investigated the influence on the minimum alveolar anesthetic concentration of isoflurane and concluded that landiolol does not alter the antinociceptive effect of isoflurane, suggesting that landiolol does not influence the anesthetic potency of inhaled anesthetics.

Michael J. Laster, Yi Zhang, Edmond I. Eger, II, Dimitry Shnayderman, and James M. Sonner

Alterations in Spinal, but Not Cerebral, Cerebrospinal Fluid Na⁺ Concentrations Affect the Isoflurane Minimum Alveolar Concentration in Rats
Anesth Analg 2007 105: 661-665. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Sodium channels may mediate part of the capacity of isoflurane to produce immobility in the face of noxious stimulation.

Silvia Nunes, Leena Berg, L.-P Raittinen, Heikki Ahonen, Jussi Laranne, Leena Lindgren, Iikka Parviainen, Esko Ruokonen, and Jyrki Tenhunen

Deep Sedation with Dexmedetomidine in a Porcine Model Does Not Compromise the Viability of Free Microvascular Flap as Depicted by Microdialysis and Tissue Oxygen Tension
Anesth Analg 2007 105: 666-672. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Dexmedetomidine is a potential sedative drug after major facial reconstructive surgery, but may induce vasoconstriction in denervated flaps and thus increase the risk of tissue damage. Our data suggest that, even if used for deep sedation, dexmedetomidine does not have deleterious effects on tissue perfusion in denervated musculocutaneous flaps.

Liya Yang, Jing Zhao, Pavle S. Milutinovic, Robert J. Brosnan, Edmond I. Eger, II, and James M. Sonner

Anesthetic Properties of the Ketone Bodies ß-Hydroxybutyric Acid and Acetone
Anesth Analg 2007 105: 673-679. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The ketone bodies {beta}-hydroxybutyric acid and acetone are anesthetics in animals, and show anesthetic-like modulation of glycine and {gamma}-aminobutyric acid type A receptors at pathophysiologic concentrations.

TECHNOLOGY, COMPUTING, AND SIMULATION:

Philip J. Peyton, Michael Chong, Christopher Stuart-Andrews, Gavin J. B. Robinson, Robert Pierce, and Bruce R. Thompson

Measurement of Anesthetics in Blood Using a Conventional Infrared Clinical Gas Analyzer
Anesth Analg 2007 105: 680-687. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Measurement of anesthetic gas tension in blood using a sidestream gas analyzer is comparable in accuracy and precision to analysis by gas chromatography. This simplified approach facilitates direct studies of anesthetic vapor delivery to blood, instead of relying upon measuring exhaled gas concentrations.

Andreas Ekman, Erik Stålberg, Eva Sundman, Lars I. Eriksson, Lars Brudin, and Rolf Sandin

The Effect of Neuromuscular Block and Noxious Stimulation on Hypnosis Monitoring During Sevoflurane Anesthesia
Anesth Analg 2007 105: 688-695. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Neuromuscular blockade blunts the bispectral index and auditory-evoked potential index response to tetanic stimulation of a peripheral nerve. The degree of neuromuscular blockade may be a factor when interpreting electroencephalogram-based monitoring of the hypnotic state.

Takehiko Adachi, Kiichi Hirota, Tomoko Hara, Yukiko Sasaki, and Yasufumi Hara

Exhaled Carbon Monoxide Levels Change in Relation to Inspired Oxygen Fraction During General Anesthesia
Anesth Analg 2007 105: 696-699. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The inspired oxygen concentration influences the concentration of carbon monoxide in the blood and exhaled gases during anesthesia. Inspired oxygen concentration should be considered when interpreting measurements of exhaled carbon monoxide concentration.

Lan Zhang, Quan Gong, Hong Xiao, Chongqi Tu, and Jin Liu

Control of Blood Loss During Sacral Surgery by Aortic Balloon Occlusion (Technical Communication)
Anesth Analg 2007 105: 700-703. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: A balloon located in the abdominal aorta can be intermittently used to occlude aortic blood flow and significantly reduce blood loss and surgical time during sacrococcygeal tumor resection.

David L. McDonagh, Matthew R. McDaniel, and Terri G. Monk

The Effect of Intravenous Indigo Carmine on Near-Infrared Cerebral Oximetry (Case Report)
Anesth Analg 2007 105: 704-706. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We report four cases of intraoperative cerebral desaturations, as measured by near-infrared cerebral oximetry, after IV administration of indigo carmine. Anesthesiologists and intensivists should be aware of this effect when using cerebral oximetry.

ECONOMICS, EDUCATION, AND POLICY:

Mark Van Houdenhoven, Jeroen M. van Oostrum, Erwin W. Hans, Gerhard Wullink, and Geert Kazemier

Improving Operating Room Efficiency by Applying Bin-Packing and Portfolio Techniques to Surgical Case Scheduling
Anesth Analg 2007 105: 707-714. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Operating room departments that cannot improve efficiency by current known scheduling practices can benefit from lowering organizational barriers and adopting mathematical algorithms to their surgical case scheduling. This study demonstrates that operating room utilization can be increased by 4.5% point.

CRITICAL CARE AND TRAUMA:

Yasser Sakr, Konrad Reinhart, Stefan Hagel, Michael Kientopf, and Frank Brunkhorst

Antithrombin Levels, Morbidity, and Mortality in a Surgical Intensive Care Unit
Anesth Analg 2007 105: 715-723. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Although antithrombin levels are often low in sepsis, such levels are not related to outcome.

Takashi Hitosugi, Toshiyuki Saito, Sono Suzuki, Ieko Kubota, Emi Shoda, Toru Shimizu, and Yoshiyuki Oi

Hydroxyethyl Starch: The Effect of Molecular Weight and Degree of Substitution on Intravascular Retention In Vivo
Anesth Analg 2007 105: 724-728. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Both the molecular weight and the degree of substitution of hydroxyethyl starches modify their retention within the circulation. The properties of individual hydroxyethyl starch solutions need to be further characterized.

Lars Kjærsgaard Hansen, Jacob Koefoed-Nielsen, Jonas Nielsen, and Anders Larsson

Are Selective Lung Recruitment Maneuvers Hemodynamically Safe in Severe Hypovolemia? An Experimental Study in Hypovolemic Pigs with Lobar Collapse
Anesth Analg 2007 105: 729-734. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Selective lung recruitment maneuvers may facilitate safe reinflation of collapsed lung areas, even in the case of hemodynamic instability.

Jin-Tae Kim, Jeong-Rim Lee, Jae-Kwang Kim, Seung Zhoo Yoon, Yunseok Jeon, Jae-Hyon Bahk, Ki-Bong Kim, Chong-Sung Kim, Young-Jin Lim, Hee-Soo Kim, and Seong-Deok Kim

The Carina as a Useful Radiographic Landmark for Positioning the Intraaortic Balloon Pump
Anesth Analg 2007 105: 735-738. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The carina in a chest radiograph can be used as a guide for positioning the intraaortic balloon pump.

NEUROSURGICAL ANESTHESIOLOGY:

Alex Bekker, Michael Haile, Kevin Gingrich, Leslie Wenning, Alex Gorny, David Quartermain, and Thomas Blanck

Physostigmine Reverses Cognitive Dysfunction Caused by Moderate Hypoxia in Adult Mice
Anesth Analg 2007 105: 739-743. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Mild hypoxia (O2 saturation 70%) produces a transient impairment of short-term memory in adult mice. Physostigmine administered after hypoxic insult reverses cognitive dysfunction.

Norbert Zoremba, Joerg Schnoor, Michael Berens, Ralf Kuhlen, and Rolf Rossaint

Brain Metabolism During a Decrease in Cerebral Perfusion Pressure Caused by an Elevated Intracranial Pressure in the Porcine Neocortex
Anesth Analg 2007 105: 744-750. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: In this porcine model of increased intracranial pressure and decreased cerebral perfusion pressure, threshold values for metabolic evidence of ischemia were 30 and 40 mm Hg, respectively. Therefore, lower ICP and CPP values than expected are tolerable until ischemic changes occur.

OBSTETRIC ANESTHESIOLOGY:

Cynthia A. Wong, Robert J. McCarthy, Paul C. Fitzgerald, Kiril Raikoff, and Michael J. Avram

Gastric Emptying of Water in Obese Pregnant Women at Term
Anesth Analg 2007 105: 751-755. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Findings from this crossover study demonstrate that gastric emptying in obese, term nonlaboring pregnant volunteers did not differ after the ingestion of 50 mL compared with that after 300 mL water. These findings suggest that allowing obese pregnant women to ingest clear liquids may not increase their risk of aspiration.

Yaakov Beilin, Nicole R. Guinn, Howard H. Bernstein, Jeff Zahn, Sabera Hossain, and Carol A. Bodian

Local Anesthetics and Mode of Delivery: Bupivacaine Versus Ropivacaine Versus Levobupivacaine
Anesth Analg 2007 105: 756-763. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The findings of this prospective randomized study suggest that epidural bupivacaine, ropivacaine, and levobupivacaine all confer adequate labor epidural analgesia, with no significant influence on the mode of delivery, duration of labor, or neonatal outcome.

Miriam J. P. Harnett, Nollag O’Rourke, Mary Walsh, Jean Marie Carabuena, and Scott Segal

Transdermal Scopolamine for Prevention of Intrathecal Morphine-Induced Nausea and Vomiting After Cesarean Delivery
Anesth Analg 2007 105: 764-769. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We compared the postoperative antiemetic efficacy of scopolamine, ondansetron, and placebo in patients receiving intrathecal morphine undergoing cesarean delivery. The rates of all emesis were reduced by one-third by transdermal scopolamine (TDS) or ondansetron. Scopolamine is an effective medication for prophylactic use in these parturients. Its use, however, was associated with a higher incidence of side effects such as dry mouth and blurry vision.

Chiu-Ming Ho and Kwok-Hon Chan

Posterior Reversible Encephalopathy Syndrome with Vasospasm in a Postpartum Woman After Postdural Puncture Headache Following Spinal Anesthesia (Case Report)
Anesth Analg 2007 105: 770-772. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This report describes the successful management of a postpartum woman with cerebral vasospasm-induced posterior reversible encephalopathy syndrome. This syndrome is associated with irreversible brain damage if not recognized or treated incorrectly.

GENERAL ARTICLES:

Oliver Kimberger, Edith Fleischmann, Sebastian Brandt, André Kugener, Barbara Kabon, Luzius Hiltebrand, Vladimir Krejci, and Andrea Kurz

Supplemental Oxygen, but Not Supplemental Crystalloid Fluid, Increases Tissue Oxygen Tension in Healthy and Anastomotic Colon in Pigs
Anesth Analg 2007 105: 773-779. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Supplemental oxygen rapidly increases tissue oxygen tension in healthy, perianastomotic, and anastomotic colon tissue. Supplemental crystalloid fluid does not improve oxygenation of these tissues.

Victor W. Xia, Rafik M. Ghobrial, Bin Du, Tabitha Chen, Ke-Qin Hu, Jonathan R. Hiatt, Ronald W. Busuttil, and Randolph H. Steadman

Predictors of Hyperkalemia in the Prereperfusion, Early Postreperfusion, and Late Postreperfusion Periods During Adult Liver Transplantation
Anesth Analg 2007 105: 780-785. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The authors retrospectively analyzed 1124 adult liver transplants and identified several recipient, donor, laboratory, and intraoperative predictors of hyperkalemia in the prereperfusion, early postreperfusion, and late postreperfusion periods.

Zahid Hussain Khan, Mahin Gharabaghian, Ferozeh Nilli, Mehdi Ghiamat, and Mostafa Mohammadi

Easy Endotracheal Intubation of a Patient Suffering from Both Cushing's and Nelson's Syndromes Predicted by the Upper Lip Bite Test Despite a Mallampati Class 4 Airway (Case Report)
Anesth Analg 2007 105: 786-787. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The upper lip bite test correctly predicted an easy intubation in a patient with a Mallampati Class 4 airway.

ANALGESIA:

Spencer S. Liu and Christopher L. Wu

The Effect of Analgesic Technique on Postoperative Patient-Reported Outcomes Including Analgesia: A Systematic Review
Anesth Analg 2007 105: 789-808. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Data suggest that improved postoperative analgesia leads to better patient outcomes, but there is insufficient evidence to support subsequent improvements in patient-centered outcomes such as quality of life and quality of recovery. Further studies are needed to develop validated patient-reported instruments and to assess the effect of analgesic techniques on patient-reported outcomes in the perioperative period.

Shinichi Ishikawa, Masataka Yokoyama, Satoshi Mizobuchi, Hidenori Hashimoto, Eiji Moriyama, and Kiyoshi Morita

Epidural Blood Patch Therapy for Chronic Whiplash-Associated Disorder
Anesth Analg 2007 105: 809-814. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Cerebral spinal fluid leaks may be an etiology for whiplash-associated disorder and can be treated with epidural blood patch.

Valéria Martinez, Dominique Fletcher, Didier Bouhassira, Daniel I. Sessler, and Marcel Chauvin

The Evolution of Primary Hyperalgesia in Orthopedic Surgery: Quantitative Sensory Testing and Clinical Evaluation Before and After Total Knee Arthroplasty
Anesth Analg 2007 105: 815-821. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Peripheral sensitization plays an important role in pain associated with knee arthroplasty in both the preoperative and postoperative periods.

Supranee Niruthisard, Thewarug Werawataganon, Pavena Bunburaphong, Montson Ussawanophakiat, Chuthayuth Wongsakornchaikul, and Kusonsi Toleb

Improving the Analgesic Efficacy of Intrathecal Morphine with Parecoxib After Total Abdominal Hysterectomy (Brief Report)
Anesth Analg 2007 105: 822-824. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Perioperative parecoxib enhanced the postoperative analgesia of intrathecal morphine/bupivacaine and improved satisfaction in patients undergoing total abdominal hysterectomy.

Igor Kissin, Cristina F. Freitas, Howard L. Mulhern, and Umberto DeGirolami

Sciatic Nerve Block with Resiniferatoxin: An Electron Microscopic Study of Unmyelinated Fibers in the Rat
Anesth Analg 2007 105: 825-831. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: A single injection of resiniferatoxin can block the rat sciatic for up to 3-wk duration without any significant damage to the unmyelinated nerve fibers.

Ryoji Iida, Ken-ichi Iwasaki, Jitsu Kato, Shigeru Saeki, and Setsuro Ogawa

Reflex Sympathetic Activity After Intravenous Administration of Midazolam in Anesthetized Cats
Anesth Analg 2007 105: 832-837. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: IV midazolam produces dose-related effects on somatosympathetic A{delta} and C reflex discharges in cats. The effect is enhanced in decerebrate cats.

Michael A. Thacker, Anna K. Clark, Fabien Marchand, and Stephen B. McMahon

Pathophysiology of Peripheral Neuropathic Pain: Immune Cells and Molecules (Review Article)
Anesth Analg 2007 105: 838-847. [Abstract] [Full Text] [PDF]  

Sanjay K. Sinha, Jonathan H. Abrams, and Robert S. Weller

Ultrasound-Guided Interscalene Needle Placement Produces Successful Anesthesia Regardless of Motor Stimulation Above or Below 0.5 mA
Anesth Analg 2007 105: 848-852. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: During ultrasound-guided interscalene block using nerve stimulation, the observed motor response below or above 0.5 mA had no impact on success or duration of upper trunk block.

Ken Kardash, Don Hickey, Michael J. Tessler, Stacey Payne, David Zukor, and Ana Miriam Velly

Obturator Versus Femoral Nerve Block for Analgesia After Total Knee Arthroplasty
Anesth Analg 2007 105: 853-858. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Single-injection femoral nerve block improves multimodal analgesia after total knee arthroplasty. However, this effect does not persist beyond the day of surgery. Obturator block alone provides no benefit.

François-Xavier Rose, Jean-Pierre Estebe, Maja Ratajczak, Eric Wodey, François Chevanne, Gilles Dollo, David Bec, Jean-Marc Malinovsky, Claude Ecoffey, and Pascal Le Corre

Epidural, Intrathecal Pharmacokinetics, and Intrathecal Bioavailability of Ropivacaine
Anesth Analg 2007 105: 859-867. [Abstract] [Full Text] [PDF] [Data Supplement]   

IMPLICATIONS: Using an animal model, we showed that the drug dispositions in the intrathecal and epidural compartments are different, and that the intrathecal bioavailability of ropivacaine after epidural administration is low, and highly variable.

W. Anton Visser, Maarten J. P. G. van Eerd, Robert van Seventer, Mathieu J. M. Gielen, Janneke L. P. Giele, and Gert J. Scheffer

Continuous Positive Airway Pressure Breathing Increases Cranial Spread of Sensory Blockade After Cervicothoracic Epidural Injection of Lidocaine
Anesth Analg 2007 105: 868-871. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We have demonstrated that airway pressure is a factor in determining the distribution of sensory blockade in cervicothoracic epidural anesthesia.

Hoang C. Nguyen, Erwin Fath, Sebastian Wirtz, and Tareg Bey

Transscalene Brachial Plexus Block: A New Posterolateral Approach for Brachial Plexus Block (Brief Report)
Anesth Analg 2007 105: 872-875. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: A new posterolateral approach to the proximal brachial plexus, the transscalene block, is associated with an 85% success rate and only minor (transient) side effects. Additional studies are needed to compare the efficacy and safety of the transscalene block with other approaches.

LETTERS TO THE EDITOR:

Edwin J. Rosman

Pseudo-Emergent Use of an Investigational Drug
Anesth Analg 2007 105: 876. [Full Text] [PDF]  

Steven L. Shafer

Pseudo-Emergent Use of an Investigational Drug
Anesth Analg 2007 105: 876. [Full Text] [PDF]  

Avishai Ziser

Was It a True Emergency?
Anesth Analg 2007 105: 876-877. [Full Text] [PDF]  

Philip M. Jones and Timothy P. Turkstra

Urgent Usage of Sugammadex to Treat Residual Neuromuscular Blockade in the PACU
Anesth Analg 2007 105: 877. [Full Text] [PDF]  

David Wax

Where's the Fire?
Anesth Analg 2007 105: 877-878. [Full Text] [PDF]  

Paul F. White, Gary Hill, and Adam Lenz

Where's the Fire?
Anesth Analg 2007 105: 878. [Full Text] [PDF]  

Rick Bjerke

Survey of Specialists Shows We Are Not Special
Anesth Analg 2007 105: 879. [Full Text] [PDF]  

Felipe Urdaneta and Nikolaus Gravenstein

Central Venous Catheter Insertion: It is Finally Time to Start Looking
Anesth Analg 2007 105: 879. [Full Text] [PDF]  

Peter Bailey, Michael Eaton, and Scott McIntosh

Central Venous Catheter Insertion: It is Finally Time to Start Looking
Anesth Analg 2007 105: 879-880. [Full Text] [PDF]  

Steven J. Fowler

Risk of a Severe Neurological Complication After Regional Anesthesia Should Be Individualized
Anesth Analg 2007 105: 880-881. [Full Text] [PDF]  

Richard Brull, Colin J.L. McCartney, Vincent W.S. Chan, and Hossam El-Beheiry

Risk of a Severe Neurological Complication After Regional Anesthesia Should Be Individualized
Anesth Analg 2007 105: 881. [Full Text] [PDF]  

Andrew Davidson, Mary Ellen McCann, and Neil Morton

Anesthesia Neurotoxicity in Neonates: The Need for Clinical Research
Anesth Analg 2007 105: 881-882. [Full Text] [PDF]  

Richard Rowe

Neurotoxicity of Anesthetic Agents in Children
Anesth Analg 2007 105: 882. [Full Text] [PDF]  

Steven L. Shafer

Neurotoxicity of Anesthetic Agents in Children
Anesth Analg 2007 105: 882-883. [Full Text] [PDF]  

Yasuyuki Shibata, Yuko Sato, Yoshihiro Fujiwara, and Toru Komatsu

Transversus Abdominis Plane Block
Anesth Analg 2007 105: 883. [Full Text] [PDF]  

John G. McDonnell and John G. Laffey

Transversus Abdominis Plane Block
Anesth Analg 2007 105: 883. [Full Text] [PDF]  

Aaron F. Kopman

Sugammadex–Rocuronium Dosing
Anesth Analg 2007 105: 883-884. [Full Text] [PDF]  

Scott Groudine

Sugammadex–Rocuronium Dosing
Anesth Analg 2007 105: 884. [Full Text] [PDF]  

Raja Jayaram

Standards Expected While Reporting a Critical Incident
Anesth Analg 2007 105: 884. [Full Text] [PDF]  

Rohna Sinclair and Rahul R. Bajekal

Vagal Nerve Stimulation and Reflux
Anesth Analg 2007 105: 884-885. [Full Text] [PDF]  

Kevin W. Hatton and Brenda G. Fahy

Vagal Nerve Stimulation and Reflux
Anesth Analg 2007 105: 885. [Full Text] [PDF]  

Gisela Scharbert and Sibylle Kozek-Langenecker

Limitations of In Vitro Experiments on Hydroxyethyl Starch Solutions
Anesth Analg 2007 105: 885. [Full Text] [PDF]  

Joachim Boldt, Michael Wolf, and Andinet Mengistu

Limitations of In Vitro Experiments on Hydroxyethyl Starch Solutions
Anesth Analg 2007 105: 885-886. [Full Text] [PDF]  

Pierre Pandin and Olivier Dewitte

Open Low-Field Intraoperative MRI for Transsphenoidal Pituitary Surgery
Anesth Analg 2007 105: 886. [Full Text] [PDF]  

Gaab Soo Kim, Mi Sook Gwak, and Justin Sang Ko

Donor Difference (Living Versus Cadaver) Rather Than Preoperative Recipient's Status Affects Transfusion Requirements in Liver Transplantation
Anesth Analg 2007 105: 886-887. [Full Text] [PDF]  

Hemanshu Prabhakar, Zulfiqar Ali, Girija P. Rath, and Deepak Singh

Zero Bispectral Index During Coil Embolization of an Intracranial Aneurysm
Anesth Analg 2007 105: 887-888. [Full Text] [PDF]  

Yoshihiro Fujiwara, Yutaka Sato, Masato Kitayama, Yasuyuki Shibata, Toru Komatsu, and Kazuyoshi Hirota

Obturator Nerve Block Using Ultrasound Guidance
Anesth Analg 2007 105: 888-889. [Full Text] [PDF]  

C. Barker, P. Jefferson, and D. R. Ball

Portable Ultrasound to Diagnose True Radial Artery Aneurysm
Anesth Analg 2007 105: 890-891. [Full Text] [PDF]  

David C. Kramer, Joyce C. Lo, Ronit Gilad, and Arthur Jenkins, III

Fiberoptic Scope as a Rescue Device in an Anesthetized Patient in the Prone Position
Anesth Analg 2007 105: 890. [Full Text] [PDF]  

Charles Schrock, Joseph Kras, and Alex Visuara

Unclear Methodology for Anesthesia Machine Checkout
Anesth Analg 2007 105: 891-892. [Full Text] [PDF]  

Jin-Tae Kim, Tae-Gyoon Yoon, Hee-Soo Kim, Chong-Sung Kim, and Seong-Deok Kim

Simple Multiport Adaptor for Selective Lung Ventilation in Pediatric Patients
Anesth Analg 2007 105: 892. [Full Text] [PDF]  

Gregory B. Hammer

An Alternative Airway Adaptor for Single-Lung Ventilation in Infants
Anesth Analg 2007 105: 892-893. [Full Text] [PDF]  

BOOK AND MULTIMEDIA REVIEWS:

Matthew Aldrich

Anesthesiology Board Review, 2nd ed.
Anesth Analg 2007 105: 894. [Full Text] [PDF]  

Holly Muir

Atlas of Airway Management: Techniques and Tools
Anesth Analg 2007 105: 894-895. [Full Text] [PDF]  

Martin M. Stechert

A Practical Approach to Transesophageal Echocardiography on PDA
Anesth Analg 2007 105: 895. [Full Text] [PDF]  

Richard B. Patt

Current Diagnosis and Treatment of Pain
Anesth Analg 2007 105: 895-896. [Full Text] [PDF]  

LIST OF BOOKS RECEIVED FOR ANESTHESIA AND ANALGESIA JUNE 2007
Anesth Analg 2007 105: 896. [Full Text] [PDF]  

ERRATA:

ERRATUM
Anesth Analg 2007 105: 695. [Full Text] [PDF]  

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