Anesth Analg 2007 105: 1287-1292.
[Abstract]
[Full Text]
[PDF]
IMPLICATIONS: Inhaled anesthetics enhanced the actions of {gamma}-aminobutyric acid (GABA) on GABAA receptors. However, at equivalent minimal alveolar anesthetic concentration multiples, the magnitudes of these actions vary dramatically among anesthetics. In general, inhaled anesthetics (aromatic and clinical) that inhibit N-methyl-d-aspartate receptor currents most, enhance GABAA receptor currents least (and vice versa).