GUEST REVIEWER LIST:

GUEST REVIEWER LIST APRIL 1, 2007–SEPTEMBER 30, 2007
Anesth Analg 2007 105: E1-E5. [Full Text] [PDF]  

EDITORIALS:

Honorio T. Benzon

Studies on Diagnostic Injections and Surgery for Low Back Pain: Problems, Advances, and Opportunities
Anesth Analg 2007 105: 1523-1525. [Full Text] [PDF]  

Spencer S. Liu and Emory N. Brown

Will Seeing Become Believing?
Anesth Analg 2007 105: 1526-1527. [Full Text] [PDF]  

Peter S. A. Glass and Paul F. White

Practice Guidelines for the Management of Postoperative Nausea and Vomiting: Past, Present, and Future
Anesth Analg 2007 105: 1528-1529. [Full Text] [PDF]  

Ronald S. Adler

The Use of Compact Ultrasound in Anesthesia: Friend or Foe
Anesth Analg 2007 105: 1530-1532. [Full Text] [PDF]  

CARDIOVASCULAR ANESTHESIOLOGY:

Jean-Luc Hanouz, Lan Zhu, Sandrine Lemoine, Charline Durand, Olivier Lepage, Massimo Massetti, André Khayat, Benoît Plaud, and Jean-Louis Gérard

Reactive Oxygen Species Mediate Sevoflurane- and Desflurane-Induced Preconditioning in Isolated Human Right Atria In Vitro
Anesth Analg 2007 105: 1534-1539. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Sevoflurane and desflurane precondition isolated human myocardium through production of reactive oxygen species.

François J. Singelyn, Cees C.P.M. Verheyen, Franco Piovella, Hugo K. Van Aken, Nadia Rosencher for the EXPERT Study Investigators

The Safety and Efficacy of Extended Thromboprophylaxis With Fondaparinux After Major Orthopedic Surgery of the Lower Limb With or Without a Neuraxial or Deep Peripheral Nerve Catheter: The EXPERT Study
Anesth Analg 2007 105: 1540-1547. [Abstract] [Full Text] [PDF] [Data Supplement]   

IMPLICATIONS: This observational study substantiated the clinical value of once-daily 2.5 mg fondaparinux given for 4 {+/-} 1 wk after major orthopedic lower limb surgery. The clinical value of fondaparinux was also observed in patients in whom specific recommendations for neuraxial/deep peripheral indwelling catheter removal were applied.

Timo Laitio, Jouko Jalonen, Tom Kuusela, and Harry Scheinin

The Role of Heart Rate Variability in Risk Stratification for Adverse Postoperative Cardiac Events (Review Article)
Anesth Analg 2007 105: 1548-1560. [Abstract] [Full Text] [PDF] [CME]  

Toby N. Weingarten, Brian A. Hall, Brian F. Richardson, Roger E. Hofer, and Juraj Sprung

Periorbital Ecchymoses During General Anesthesia in a Patient with Primary Amyloidosis: A Harbinger for Bleeding? (Case Report)
Anesth Analg 2007 105: 1561-1563. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: In primary amyloidosis, proliferation of plasma cells lead to an increased production of monoclonal immunoglobulins, some of which can form amyloid chains. We describe a patient who developed periorbital blistering purpura under the adhesive tape that was attributed to capillary fragility associated with deposition of amyloid.

Ralph Slepian, Arash Salemi, James Min, and Nikolaos Skubas

A Hypo-Echoic, Intramyocardial Space: Echocardiographic Characteristics of an Intramyocardial Dissecting Hematoma (Echo Rounds)
Anesth Analg 2007 105: 1564-1566. [Full Text] [PDF] [Echo Loops]   

David A. Pybus

Thrombotic Occlusion of a Bileaflet, Mechanical Mitral Valve (Echo Rounds)
Anesth Analg 2007 105: 1567-1568. [Full Text] [PDF] [Echo Loop]   

Anjan M. Shah, Shannon M. Rivenes, Charles D. Fraser, and Wanda C. Miller-Hance

Aneurysm of the Atrioventricular Membranous Septum Appearing as a Right Atrial Cystic Mass (Echo Rounds)
Anesth Analg 2007 105: 1569-1571. [Full Text] [PDF] [Echo Loops]   

Surita Sidhu, Caroline Goyer, Roupen Hatzakorzian, Jean-Francois Olivier, Benoit Devarennes, Annie V. Cote, and William Li Pi Shan

Transesophageal Echocardiographic Detection of Intracardiac Bioglue® Postmitral Valve Replacement (Echo Rounds)
Anesth Analg 2007 105: 1572-1573. [Full Text] [PDF] [Echo Loops]   

Alina Nicoara, G. Burkhard Mackensen, Mihai V. Podgoreanu, Carmelo A. Milano, Joseph P. Mathew, and Madhav Swaminathan

Malpositioned Left Ventricular Assist Device Cannula: Diagnosis and Management with Transesophageal Echocardiography Guidance (Echo Rounds)
Anesth Analg 2007 105: 1574-1576. [Full Text] [PDF] [Echo Loops]   

PEDIATRIC ANESTHESIOLOGY:

Glyn D. Williams, Bridget M. Philip, Larry F. Chu, M. Gail Boltz, Komal Kamra, Heidi Terwey, Gregory B. Hammer, Stanton B. Perry, Jeffrey A. Feinstein, and Chandra Ramamoorthy

Ketamine Does Not Increase Pulmonary Vascular Resistance in Children with Pulmonary Hypertension Undergoing Sevoflurane Anesthesia and Spontaneous Ventilation
Anesth Analg 2007 105: 1578-1584. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Ketamine did not exacerbate pulmonary vascular resistance in children with pulmonary hypertension who were anesthetized with sevoflurane in air and breathing spontaneously.

Javier Garcia-Fernandez, Gerardo Tusman, Fernando Suarez-Sipmann, Julio Llorens, Marina Soro, and Javier F. Belda

Programming Pressure Support Ventilation in Pediatric Patients in Ambulatory Surgery with a Laryngeal Mask Airway
Anesth Analg 2007 105: 1585-1591. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This study evaluates the ability to administer positive pressure support ventilation through a laryngeal mask airway to anesthetized, spontaneously breathing children.

Peter Kranke, Leopold H. Eberhart, Hakki Toker, Norbert Roewer, Hinnerk Wulf, and Peter Kiefer

A Prospective Evaluation of the POVOC Score for the Prediction of Postoperative Vomiting in Children
Anesth Analg 2007 105: 1592-1597. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This evaluation trial suggests that the POVOC score for the prediction of postoperative vomiting (PV) in children allows for the risk for PV to be estimated in various patient populations and in different settings with acceptable accuracy.

Oliver J. Liakopoulos, Jonathan K. Ho, Aaron Yezbick, Elizabeth Sanchez, Clayton Naddell, Gerald D. Buckberg, Ryan Crowley, and Aman Mahajan

An Experimental and Clinical Evaluation of a Novel Central Venous Catheter with Integrated Oximetry for Pediatric Patients Undergoing Cardiac Surgery
Anesth Analg 2007 105: 1598-1604. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Central venous oxygen saturation (ScvO2) accurately reflects cardiocirculatory function. However, venous catheters do not allow continuous measurement of ScvO2 in pediatric patients. Using an experimental and clinical approach, we determined the accuracy of a novel pediatric central venous catheter with integrated fiberoptic oximetry, correlated ScvO2 to periprocedural vital variables, and tested its feasibility in pediatric cardiac surgery patients.

Harshad Gurnaney, Arjunan Ganesh, and Giovanni Cucchiaro

The Relationship Between Current Intensity for Nerve Stimulation and Success of Peripheral Nerve Blocks Performed in Pediatric Patients Under General Anesthesia
Anesth Analg 2007 105: 1605-1609. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Peripheral nerve blocks performed in pediatric patients under general anesthesia with a higher stimulation threshold (0.5 1 mA) have a similar success rate to those performed with lower stimulation thresholds (<=0.5 mA).

Kah-Lok Chan, Robyn G. Summerhayes, Vera Ignjatovic, Stephen B. Horton, and Paul T. Monagle

Reference Values for Kaolin-Activated Thromboelastography in Healthy Children
Anesth Analg 2007 105: 1610-1613. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We present reference values for kaolin-activated thromboelastography (TEG(R)) in healthy children. Accurate interpretation of pediatric TEG results requires comparison to reference values that are age-, analyzer-, and activator-specific.

AMBULATORY ANESTHESIOLOGY:

Tong J. Gan, Tricia A. Meyer, Christian C. Apfel, Frances Chung, Peter J. Davis, Ashraf S. Habib, Vallire D. Hooper, Anthony L. Kovac, Peter Kranke, Paul Myles, Beverly K. Philip, Gregory Samsa, Daniel I. Sessler, James Temo, Martin R. Tramèr, Craig Vander Kolk, and Mehernoor Watcha

Society for Ambulatory Anesthesia Guidelines for the Management of Postoperative Nausea and Vomiting (Special Article)
Anesth Analg 2007 105: 1615-1628. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Evidence-based guidelines developed by an international multidisciplinary panel of experts and endorsed by Society for Ambulatory Anesthesia for the management of postoperative nausea and vomiting.

ANESTHETIC PHARMACOLOGY:

Tom De Smet, Michel M. R. F. Struys, Scott Greenwald, Eric P. Mortier, and Steven L. Shafer

Estimation of Optimal Modeling Weights for a Bayesian-Based Closed-Loop System for Propofol Administration Using the Bispectral Index as a Controlled Variable: A Simulation Study
Anesth Analg 2007 105: 1629-1638. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Bispectral Index-guided closed-loop administration of propofol could be optimized by implementing Bayesian technology. We applied simulations to select the Bayesian variances yielding the optimal closed-loop control system for propofol administration and found that this technique resulted in stable control and can be introduced safely into clinical testing.

Tadayoshi Kurita, Kotaro Takata, Masahiro Uraoka, Koji Morita, Yoshimitsu Sanjo, Takasumi Katoh, and Shigehito Sato

The Influence of Hemorrhagic Shock on the Minimum Alveolar Anesthetic Concentration of Isoflurane in a Swine Model
Anesth Analg 2007 105: 1639-1643. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Hemorrhagic shock decreased the minimum alveolar concentration of isoflurane depending on the severity of the shock, although the hypnotic effect shows great resistance to hemorrhagic shock. We propose that activation of the endogenous opioid system during hemorrhagic shock explains these phenomena.

Andrea Paris, Lutz Hein, Marc Brede, Philipp-Alexander Brand, Jens Scholz, and Peter H. Tonner

The Anesthetic Effects of Etomidate: Species-Specific Interaction with ₂-Adrenoceptors
Anesth Analg 2007 105: 1644-1649. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Etomidate has structural and clinical similarities to {alpha}2-adrenoceptor agonists. Atipamezole, an {alpha}2-adrenoceptor agonist, significantly increased the half-maximal effective concentration of etomidate in tadpoles. In contrast, the sedative effects of etomidate were not reduced in wild-type or transgenic mice lacking the {alpha}2-adrenoceptor subtype. Thus the interaction between etomidate and {alpha}2-adrenoceptors is species-specific.

Toni L. Jones, Adam C. Lustig, and Linda S. Sorkin

Secondary Hyperalgesia in the Postoperative Pain Model Is Dependent on Spinal Calcium/Calmodulin-Dependent Protein Kinase II Activation
Anesth Analg 2007 105: 1650-1656. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Findings in the present study indicate that targeting spinal CaMKII{alpha} might effectively reduce spinal-mediated pain behavior during the immediate postoperative period.

Philipp Lirk, Ingrid Haller, Hans Peter Colvin, Silke Frauscher, Lukas Kirchmair, Peter Gerner, and Lars Klimaschewski

In Vitro, Lidocaine-Induced Axonal Injury Is Prevented by Peripheral Inhibition of the p38 Mitogen-Activated Protein Kinase, but Not by Inhibiting Caspase Activity
Anesth Analg 2007 105: 1657-1664. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Compartmented neuron cultures allow for axon and soma to be selectively incubated. We provide first, albeit indirect, evidence that cell death after local anesthetic application may be caused by different processes, depending upon whether the entire cell, or only the axon, is incubated.

Robert C. Dutton, Jason M. Cuellar, Edmond I. Eger, II, Joseph F. Antognini, and Earl Carstens

Temporal and Spatial Determinants of Sacral Dorsal Horn Neuronal Windup in Relation to Isoflurane-Induced Immobility
Anesth Analg 2007 105: 1665-1674. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Windup of sacral dorsal horn neurons is a N-methyl-d-aspartate receptor-dependent increase in progressive response to repetitive C-fiber stimulation that is enhanced by increasing stimulus frequency and intensity. Windup is dose-dependently reduced by isoflurane in a manner that parallels the influence of temporal and spatial summation of noxious stimuli on anesthetic requirements.

Charles W. Buffington, Michael J. Laster, Katarzyna Jankowska, and Edmond I. Eger, II

Concentrations of Isoflurane Exceeding Those Used Clinically Slightly Increase the Affinity of Methane, but Not Toluene, for Water
Anesth Analg 2007 105: 1675-1680. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The low aqueous solubility of nonpolar groups (hydrophobicity) is a powerful thermodynamic force determining the conformation, and thus the function, of macromolecules such as proteins. The inhaled anesthetic isoflurane does not affect the aqueous solubility of two simple nonpolar molecules (methane and toluene) in concentrations used for clinical anesthesia. These results argue against alteration in the aqueous solubility of nonpolar groups on macromolecules as a primary component of the mechanism of action of inhaled anesthetics.

TECHNOLOGY, COMPUTING, AND SIMULATION:

Anupama Wadhwa, Ryu Komatsu, Mukadder Orhan-Sungur, Pamela Barnes, JangHyeok In, Daniel I. Sessler, and Rainer Lenhardt

New Circulating-Water Devices Warm More Quickly than Forced-Air in Volunteers
Anesth Analg 2007 105: 1681-1687. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Rewarming anesthetized volunteers from a core temperature of 34{degrees}C 36{degrees}C was accomplished 25% more rapidly using Kimberly Clark energy transfer pads than with the Allon circulating-water garment and twice as fast as with a forced-air warming system.

Tomohiro Kiya, Michiaki Yamakage, Tomo Hayase, Jun-Ichi Satoh, and Akiyoshi Namiki

The Usefulness of an Earphone-Type Infrared Tympanic Thermometer for Intraoperative Core Temperature Monitoring
Anesth Analg 2007 105: 1688-1692. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: An earphone-type infrared tympanic thermometer was compared with esophageal temperature measurements in both general and cardiac surgery patients and found to agree within clinically acceptable limits for continuous core temperature monitoring.

ECONOMICS, EDUCATION, AND POLICY:

James E. Bost, Brian A. Williams, Matthew T. Bottegal, Qianyu Dang, and Doris M. Rubio

The 8-Item Short-Form Health Survey and the Physical Comfort Composite Score of the Quality of Recovery 40-Item Scale Provide the Most Responsive Assessments of Pain, Physical Function, and Mental Function During the First 4 Days After Ambulatory Knee Surgery with Regional Anesthesia
Anesth Analg 2007 105: 1693-1700. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: For outpatients undergoing anterior cruciate ligament reconstruction and receiving regional anesthesia, the SF-8 is sufficient to assess postoperative pain, physical function, and mental function. Only the Quality of Recovery from Anesthesia (QoR)-40 physical comfort composite, but not the remainder of the QoR-40, was additionally helpful when compared with the SF-8.

Franklin Dexter, Yan Xiao, Angella J. Dow, Melissa M. Strader, Danny Ho, and Ruth E. Wachtel

Coordination of Appointments for Anesthesia Care Outside of Operating Rooms Using an Enterprise-Wide Scheduling System
Anesth Analg 2007 105: 1701-1710. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: An anesthesia department implemented scheduling of anesthetics outside of operating rooms by clerks and nurses from other departments using its hospital's enterprise-wide scheduling system. Experiments showed that improvements in the consistency and accuracy of patient instructions were sensitive both to the user interface and to the probabilities of anesthetics starting earlier than scheduled.

David B. Wax and David L. Reich

Changes in Utilization of Intraoperative Laboratory Testing Associated with the Introduction of Point-of-Care Testing Devices in an Academic Department (Brief Report)
Anesth Analg 2007 105: 1711-1713. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The frequency of intraoperative blood testing for noncardiothoracic cases was 13% before and after installation of point-of-care testing devices at a hospital.

CRITICAL CARE AND TRAUMA:

Takashi Kawano, Katsuya Tanaka, Hossein Nazari, Shuzo Oshita, Akira Takahashi, and Yutaka Nakaya

The Effects of Extracellular pH on Vasopressin Inhibition of ATP-Sensitive K⁺ Channels in Vascular Smooth Muscle Cells
Anesth Analg 2007 105: 1714-1719. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The effects of arginine vasopressin in vascular KATP channels are enhanced by extracellular acidification, hence arginine vasopressin-induced vasoconstriction may be enhanced in shock.

Donn Marciniak and Charles E. Smith

Emergent Retrograde Tracheal Intubation with a Gum-Elastic Bougie in a Trauma Patient (Case Report)
Anesth Analg 2007 105: 1720-1721. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The gum-elastic bougie can be used for retrogade intubation when the trachea is open.

NEUROSURGICAL ANESTHESIA:

Tetsuro Shirasaka, De-Lai Qiu, Hiroshi Kannan, and Mayumi Takasaki

The Effects of Centrally Administered Dexmedetomidine on Cardiovascular and Sympathetic Function in Conscious Rats
Anesth Analg 2007 105: 1722-1728. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The intracerebroventricular administration of dexmedetomidine to conscious rats results in a reduction in arterial blood pressure through sympathetic inhibition and a decrease in heart rate by sympathetic inhibition and vagal stimulation.

Ehsan Saboory, Miron Derchansky, Mohammed Ismaili, Shokrollah S. Jahromi, Richard Brull, Peter L. Carlen, and Hossam El Beheiry

Mechanisms of Morphine Enhancement of Spontaneous Seizure Activity
Anesth Analg 2007 105: 1729-1735. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: In this in vitro study using mouse hippocampus, the proseizure effect of morphine was mediated by {micro} and {kappa} opioid receptors.

OBSTETRIC ANESTHESIOLOGY:

Paloma Toledo, Robert J. McCarthy, Bradley J. Hewlett, Paul C. Fitzgerald, and Cynthia A. Wong

The Accuracy of Blood Loss Estimation After Simulated Vaginal Delivery (Brief Report)
Anesth Analg 2007 105: 1736-1740. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Estimation of blood loss after simulated vaginal delivery using noncalibrated drapes was inaccurate, and the inaccuracy worsened as blood loss volume increased. Calibration of the vaginal delivery drape improved the accuracy of estimated blood loss.

GENERAL ARTICLES:

Madhav Swaminathan, Barbara G. Phillips-Bute, and Katherine P. Grichnik

A Bibliometric Analysis of Global Clinical Research by Anesthesia Departments
Anesth Analg 2007 105: 1741-1746. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Bibliometric analysis of clinical research publications from anesthesiology departments over a 6-yr period found that the United States leads in overall research productivity, whereas European countries have higher per capita research productivity.

Jonathan V. Roth

Bilateral Sciatic and Femoral Neuropathies, Rhabdomyolysis, and Acute Renal Failure Caused by Positioning During Radical Retropubic Prostatectomy (Case Report)
Anesth Analg 2007 105: 1747-1748. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: In the hyperlordotic position, the patient's hips are above the feet and head. A case of bilateral femoral and sciatic neuropathies caused by this position is presented.

Hitoshi Yoshida, Tetsuya Kushikata, Shizuko Kabara, Hajime Takase, Hironori Ishihara, and Kazuyoshi Hirota

Flat Electroencephalogram Caused by Carbon Dioxide Pneumoperitoneum (Case Report)
Anesth Analg 2007 105: 1749-1752. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This report demonstrates the complications of extremely high levels of CO2 when the CO2 used for peritoneal insufflation cannot be removed through increased ventilation.

Daniel C. H. Kidani and Nitin K. Shah

The Use of a Laryngeal Mask Airway After a Prolonged Suspension Laryngoscopy to Preserve a Vocal Cord Fat Graft (Case Report)
Anesth Analg 2007 105: 1753-1754. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The laryngeal mask airway may be used as a bridge, in lieu of endotracheal intubation, in microdirect laryngoscopy cases in which ventilation during emergence may be difficult and the insertion of an endotracheal tube would disrupt the surgical procedure.

ANALGESIA:

Steven P. Cohen and Robert W. Hurley

The Ability of Diagnostic Spinal Injections to Predict Surgical Outcomes (Medical Intelligence)
Anesth Analg 2007 105: 1756-1775. [Abstract] [Full Text] [PDF] [CME]  

IMPLICATIONS: The ability of diagnostic spinal injections to improve surgical outcomes remains unproven. There is strong evidence for selective nerve root blocks, although the evidence supporting the use of preoperative discography is weak. There is no evidence to support the use of facet blocks or sacroiliac joint injections before spinal fusion.

Hunter G. Hoffman, Todd L. Richards, Trevor Van Oostrom, Barbara A. Coda, Mark P. Jensen, David K. Blough, and Sam R. Sharar

The Analgesic Effects of Opioids and Immersive Virtual Reality Distraction: Evidence from Subjective and Functional Brain Imaging Assessments (Medical Intelligence)
Anesth Analg 2007 105: 1776-1783. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: In response to experimental pain, subjects reported subjective analgesia and demonstrated reductions in pain-related brain activity with either opioid administration or virtual reality distraction, whereas combining the two interventions further improved the two analgesic end points. These results provide preliminary data to support the clinical use of multimodal (e.g., combined pharmacologic and nonpharmacologic) analgesic techniques.

Asokumar Buvanendran, Amjad Ali, Travis R. Stoub, Richard A. Berger, and Jeffrey S. Kroin

The Use of Brain Positron Emission Tomography to Identify Sites of Postoperative Pain Processing With and Without Epidural Analgesia (Brief Report)
Anesth Analg 2007 105: 1784-1786. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Postsurgical pain is associated with increased brain activity in regions usually identified with acute pain.

Edward Andrew Ochroch, Andrea B. Troxel, Jonathan K. Frogel, and John T. Farrar

The Influence of Race and Socioeconomic Factors on Patient Acceptance of Perioperative Epidural Analgesia (Brief Report)
Anesth Analg 2007 105: 1787-1792. [Abstract] [Full Text] [PDF] [Data Supplement]   

IMPLICATIONS: African Americans and people of low socioeconomic standing may be less likely to accept, and thus benefit from, perioperative epidural analgesia.

Girish P. Joshi, Ralph Gertler, and Ruth Fricker

Cardiovascular Thromboembolic Adverse Effects Associated with Cyclooxygenase-2 Selective Inhibitors and Nonselective Antiinflammatory Drugs (Brief Report)
Anesth Analg 2007 105: 1793-1804. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The cardiovascular adverse effects of nonselective nonsteroidal antiinflammatory drugs and cyclooxygenase-2 selective inhibitors will likely continue to be controversial. In the meantime, careful risk/benefit assessment should be undertaken and these drugs should be used with caution in patients with cardiovascular risks.

Noor M. Gajraj

Pregabalin: Its Pharmacology and Use in Pain Management (Review Article)
Anesth Analg 2007 105: 1805-1815. [Abstract] [Full Text] [PDF]  

Aneesh Singla, Milan P. Stojanovic, Lucy Chen, and Jianren Mao

A Differential Diagnosis of Hyperalgesia, Toxicity, and Withdrawal from Intrathecal Morphine Infusion (Case Report)
Anesth Analg 2007 105: 1816-1819. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This report demonstrates the complexity of treating patients with long-term continuous intrathecal opioids when modest adjustment of the intrathecal cocktail results in a paradoxical clinical course.

Sandra M. Siegel, Jeung W. Lee, and Anne Louise Oaklander

Needlestick Distal Nerve Injury in Rats Models Symptoms of Complex Regional Pain Syndrome
Anesth Analg 2007 105: 1820-1829. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Needlestick distal nerve injury in rats models several clinical and pathological features of human chronic regional pain syndrome, suggesting that even minor distal nerve injury can cause some of the abnormalities associated with chronic regional pain syndrome.

Jiin-Tarng Liou, Fu-Chao Liu, Shi-Tai Hsin, Ching-Yue Yang, and Ping-Wing Lui

Inhibition of the Cyclic Adenosine Monophosphate Pathway Attenuates Neuropathic Pain and Reduces Phosphorylation of Cyclic Adenosine Monophosphate Response Element-Binding in the Spinal Cord After Partial Sciatic Nerve Ligation in Rats
Anesth Analg 2007 105: 1830-1837. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The present study aimed to assess the effects of spinal cyclic adenosine monophosphate (cAMP) on the nociceptive processing in a chronic neuropathic pain model. Our results showed that blockade of the cAMP pathway within 3 days could partially reverse the increase in phosphorylated cAMP response element-binding protein to partial sciatic nerve ligation-induced tactile allodynia and thermal hyperalgesia. Modulation of the cAMP pathway may be of clinical importance if there is early intervention in patients with chronic neuropathic pain.

Li Xu, Yuguang Huang, Xuerong Yu, Jianying Yue, Nan Yang, and Pingping Zuo

The Influence of p38 Mitogen-Activated Protein Kinase Inhibitor on Synthesis of Inflammatory Cytokine Tumor Necrosis Factor Alpha in Spinal Cord of Rats with Chronic Constriction Injury
Anesth Analg 2007 105: 1838-1844. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Using a specific p38 mitogen-activated protein kinase inhibitor (MAPK), we demonstrated that p38 MAPK activation is part of the signaling cascade in the spinal cord that leads to synthesis of tumor necrosis factor-alpha and contributes to mechanical allodynia in a rat chronic constriction injury model of neuropathic pain.

Brian D. Sites, Susan Durham, John D. Gallagher, and Marc L. Bertrand

The Use of Intraoperative Ultrasound by Anesthesiologists to Facilitate the Surgical Management of Peripheral Nerve Tumors of the Upper Extremity (Case Report)
Anesth Analg 2007 105: 1845-1847. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This series of four cases describes the use of intraoperative ultrasonography performed by an anesthesiologist to facilitate surgical dissection of peripheral nerve tumors.

Jytte F. Moller, Lone Nikolajsen, Svein Aage Rodt, Hanne Ronning, and Palle S. Carlsson

Thoracic Paravertebral Block for Breast Cancer Surgery: A Randomized Double-Blind Study (Case Report)
Anesth Analg 2007 105: 1848-1851. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: A multilevel paravertebral block provides good analgesia for breast surgery, but the duration of analgesia is briefer than described in previous studies.

Arno Schiferer, Carmen Gore, Laszlo Gorove, Thomas Lang, Barbara Steinlechner, Michael Zimpfer, and Alexander Kober

A Randomized Controlled Trial of Femoral Nerve Blockade Administered Preclinically for Pain Relief in Femoral Trauma (Brief Report)
Anesth Analg 2007 105: 1852-1854. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Preclinical administered femoral nerve blockade effectively decreases pain, anxiety, and heart rate in patients after femoral trauma. Regional blockade is an option to be considered for out of hospital analgesia in the hands of the trained physician.

Anna Rabinowitz, Benoît Bourdet, Vincent Minville, Clément Chassery, Antoine Pianezza, Aline Colombani, Bernard Eychenne, Kamran Samii, and Olivier Fourcade

The Paramedian Technique: A Superior Initial Approach to Continuous Spinal Anesthesia in the Elderly (Brief Report)
Anesth Analg 2007 105: 1855-1857. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: After a single attempt, the paramedian approach is associated with an increased success rate, compared with the midline approach, during continuous spinal anesthesia in elderly patients.

Stephen M. Klein, Matthew P. Fronheiser, John Reach, Karen C. Nielsen, and Stephen W. Smith

Piezoelectric Vibrating Needle and Catheter for Enhancing Ultrasound-Guided Peripheral Nerve Blocks (Technical Communication)
Anesth Analg 2007 105: 1858-1860. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This report describes a piezoelectric needle and catheter design that permits distal tip visualization using color flow Doppler ultrasound. This method may be useful to confirm the location of the needle or catheter tip when performing regional anesthesia.

LETTERS TO THE EDITOR:

Paul F. White

The Importance of Transparency in Industry-Sponsored Multicenter Clinical Studies
Anesth Analg 2007 105: 1861. [Full Text] [PDF]  

Tong J. Gan, Christian C. Apfel, Anthony Kovac, Beverly K. Philip, Neil Singla, Harold Minkowitz, Ashraf S. Habib, Alexandra Carides, Kevin J. Horgan, Judith K. Evans, and Francesca C. Lawson

The Importance of Transparency in Industry-Sponsored Multicenter Clinical Studies
Anesth Analg 2007 105: 1861-1862. [Full Text] [PDF]  

Richard K. Baumgarten

Spinal Anesthesia Research: Let’s Not Be Hasty
Anesth Analg 2007 105: 1862. [Full Text] [PDF]  

Steven L. Shafer

Spinal Anesthesia Research: Let’s Not Be Hasty
Anesth Analg 2007 105: 1862-1863. [Full Text] [PDF]  

Paul S. Pagel

When Lack of Addition Really Does Add Up
Anesth Analg 2007 105: 1863. [Full Text] [PDF]  

Hong Liu

When Lack of Addition Really Does Add Up
Anesth Analg 2007 105: 1863-1864. [Full Text] [PDF]  

Babak Roboubi

Extended Release Epidural Morphine, Far from Ideal for Postcesarean Delivery Pain Control
Anesth Analg 2007 105: 1864. [Full Text] [PDF]  

Brendan Carvalho and Edward Riley

Extended Release Epidural Morphine, Far from Ideal for Postcesarean Delivery Pain Control
Anesth Analg 2007 105: 1864-1865. [Full Text] [PDF]  

Frank Brennan, Daniel B. Carr, and Michael Cousins

The Role of Opioids in Pain Management
Anesth Analg 2007 105: 1865-1866. [Full Text] [PDF]  

Paul F. White and Henrik Kehlet

The Role of Opioids in Pain Management
Anesth Analg 2007 105: 1866. [Full Text] [PDF]  

D. John Doyle

Consumer Reports for Anesthesia Equipment: An Idea Whose Time Has Come?
Anesth Analg 2007 105: 1866-1867. [Full Text] [PDF]  

Jeffrey M. Feldman

Consumer Reports for Anesthesia Equipment: An Idea Whose Time Has Come?
Anesth Analg 2007 105: 1867. [Full Text] [PDF]  

Yatindra Kumar Batra, Sachin Kumar Gupta, and Subramanyam Rajeev

Tracheomalacia due to Short Term Ventilation After Total Hip Arthroplasty in an Adult with Long Standing Goiter
Anesth Analg 2007 105: 1867-1868. [Full Text] [PDF]  

Maximilien Gourdin, François-Valery Verstraete, Christophe Dransart, Philippe Dubois, and Edith Collard

Disruption of a Laryngeal Mask During Removal
Anesth Analg 2007 105: 1868. [Full Text] [PDF]  

Corey S. Scher, Antonio Torres, and Shira Y. Wieder

Internet Drug Access Runs Rampant
Anesth Analg 2007 105: 1868-1869. [Full Text] [PDF]  

Edmond I. Eger, II

The Ever-Useful Infrared Analyzer
Anesth Analg 2007 105: 1869. [Full Text] [PDF]  

Norman Bolden, Charles E. Smith, Dennis Auckley, Jeanne Makarski, and Ramachandra Avula

Perioperative Complications During Use of an Obstructive Sleep Apnea Protocol Following Surgery and Anesthesia
Anesth Analg 2007 105: 1869-1870. [Full Text] [PDF]  

BOOK AND MULTIMEDIA REVIEWS:

Thomas J. Conahan

Manual of Office-Based Anesthesia Procedures
Anesth Analg 2007 105: 1871. [Full Text] [PDF]  

Jordan L. Blinder and Jeffrey B. Gross

Anesthesia in Cosmetic Surgery
Anesth Analg 2007 105: 1871-1872. [Full Text] [PDF]  

LIST OF BOOKS RECEIVED FOR ANESTHESIA AND ANALGESIA
Anesth Analg 2007 105: 1872. [Full Text] [PDF]  

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