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Contents: Volume 106, Issue 6 (June 2008)   [Index by Author]       Other Issues: Previous Next
      Down EDITORIALS
      Down CARDIOVASCULAR ANESTHESIOLOGY
      Down PEDIATRIC ANESTHESIOLOGY
      Down AMBULATORY ANESTHESIOLOGY
      Down ANESTHETIC PHARMACOLOGY
      Down TECHNOLOGY, COMPUTING AND SIMULATION
      Down CTITICAL CARE AND TRAUMA
      Down CRITICAL CARE AND TRAUMA
      Down OBSTETRIC ANESTHESIOLOGY
      Down ECONOMICS, EDUCATION, AND POLICY
      Down NEUROSURGICAL ANESTHESIOLOGY
      Down GENERAL ARTICLES
      Down ANALGESIA
      Down LETTERS TO THE EDITOR
      Down BOOK AND MULTIMEDIA REVIEWS

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To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

EDITORIALS:Back

Francis X. McGowan, Jr and Peter J. Davis
Anesthetic-Related Neurotoxicity in the Developing Infant: Of Mice, Rats, Monkeys and, Possibly, Humans
Anesth Analg 2008 106: 1599-1602. [Full Text] [PDF]  

Robert Hahn
Blood, Plasma, and Red Blood Cell Volumes in Intensive Care Unit Patients
Anesth Analg 2008 106: 1603-1604. [Full Text] [PDF]  

Pekka O. Talke and Mervyn Maze
Expecting the Unexpected
Anesth Analg 2008 106: 1605-1606. [Full Text] [PDF]  

CARDIOVASCULAR ANESTHESIOLOGY:Back

George Djaiani, Mohamed Ali, Michael A. Borger, Anna Woo, Jo Carroll, Christopher Feindel, Ludwik Fedorko, Jacek Karski, and Harry Rakowski

Anesth Analg 2008 106: 1611-1618. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The use of epiaortic scanning before aortic manipulations led to modifications in intraoperative surgical management in nearly one-third of patients undergoing coronary artery bypass graft surgery. Epiaortic scanning should be considered for assessment of the proximal thoracic aorta especially for patients at high risk of neurological injury.

Mohamed H. Bakri, Hassan Nagem, Daniel I. Sessler, Ramatia Mahboobi, Jarrod Dalton, Ozan Akça, Eric E. Roselli, and Steven R. Insler

Anesth Analg 2008 106: 1619-1626. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Supplemental postoperative inspired oxygen improves arterial and sternal wound tissue oxygenation after cardiac surgery; however, oxygen insufflated locally into the occlusive dressing over the wound did not improve wound oxygenation. Since interventions that improve tissue oxygenation reduce infection risk, supplemental inspired oxygen, but not local transdermal application, may reduce wound infection risk after cardiac surgery.

Daniel Dirkmann, Alexander A. Hanke, Klaus Görlinger, and Jürgen Peters

Anesth Analg 2008 106: 1627-1632. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Human whole blood coagulation is significantly impaired by hypothermia, but not by acidosis, as studied by rotational thromboelastometry. Hypothermia and acidosis combined synergistically impair coagulation.

Susan M. Martinelli, John D. Mitchell, Richard L. McCann, Mihai V. Podgoreanu, Joseph P. Mathew, and Madhav Swaminathan
Intraoperative Transesophageal Echocardiography Diagnosis of Residual Tumor Fragment After Surgical Removal of Renal Cell Carcinoma (Echo Rounds)
Anesth Analg 2008 106: 1633-1635. [Full Text] [PDF] [Video Loops]   

Daniel T. Redford, Thomas W. Quigley, Kimberly L. Gandy, and Brent J. Barber
Transesophageal Echocardiography for the Intraoperative Evaluation and Management of a Left Ventricular Vegetation (Echo Rounds)
Anesth Analg 2008 106: 1636-1638. [Full Text] [PDF] [Video Loop]   

Junko Nakahira, Toshiyuki Sawai, Takahiro Katsumata, Hideaki Imanaka, and Toshiaki Minami
Lambl’s Excrescence on Aortic Valve Detected by Transesophageal Echocardiography (Echo Rounds)
Anesth Analg 2008 106: 1639-1640. [Full Text] [PDF] [Video Loop]   

PEDIATRIC ANESTHESIOLOGY:Back

Cheng Wang and William Slikker, Jr
(Special Article)
Anesth Analg 2008 106: 1643-1658. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: By applying pharmacogenomic and system biology approaches, along with the appropriate in vivo and in vitro nonhuman primate and rodent models, complex biological processes, such as the mechanisms underlying neuronal cell death induced by anesthetics in the developing brain, can be better understood. This understanding may further reveal the pathways involved in anesthetic-induced neuronal cell death, and suggest potential treatment regimens that protect or attenuate pediatric anesthetic toxicity.

Vesna Jevtovic-Todorovic and John W. Olney
PRO: Anesthesia-Induced Developmental Neuroapoptosis: Status of the Evidence (Editorial)
Anesth Analg 2008 106: 1659-1663. [Full Text] [PDF]  

Andreas W. Loepke, Francis X. McGowan, Jr, and Sulpicio G. Soriano
CON: The Toxic Effects of Anesthetics in the Developing Brain: The Clinical Perspective (Editorial)
Anesth Analg 2008 106: 1664-1669. [Full Text] [PDF]  

Vincent Degos, Gauthier Loron, Jean Mantz, and Pierre Gressens
(Review Article)
Anesth Analg 2008 106: 1670-1680. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Injury to the perinatal brain is a leading cause of death and disability in children. Understanding the pathophysiology of perinatal brain damage will help to identify potential targets for neuroprotective strategies.

Andreas W. Loepke and Sulpicio G. Soriano
(Review Article)
Anesth Analg 2008 106: 1681-1707. [Abstract] [Full Text] [PDF] [CME]  

IMPLICATIONS: Data obtained in developing animals have demonstrated widespread neurodegeneration after anesthesia and have led to serious questions about the safety of pediatric anesthesia. Relevant reports in animals and humans are reviewed and their pertinence to clinical practice assessed.

Robert D. Sanders, Jing Xu, Yi Shu, Antonio Fidalgo, Daqing Ma, and Mervyn Maze
(Review Article)
Anesth Analg 2008 106: 1708-1711. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Anesthesia induces apoptosis throughout the neonatal rat central nervous system, including the spinal cord; however, we have not discovered any functional consequences of the spinal cord injury.

Davide Cattano, Chainllie Young, Megan M.W. Straiko, and John W. Olney
(Brief Report)
Anesth Analg 2008 106: 1712-1714. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Propofol is used for sedation and anesthesia in pediatric and obstetric medicine. Subanesthetic exposure of infant mice to other anesthetics (ketamine, midazolam, and isoflurane) triggers neuroapoptosis in the developing brain. We now report that propofol, in subanesthetic doses, triggers neuroapoptosis in the infant mouse brain.

Vivian M. Yuen, Theresa W. Hui, Michael G. Irwin, and Man K. Yuen
(Brief Report)
Anesth Analg 2008 106: 1715-1721. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Intranasal dexmedetomidine at 1 {micro}g/kg produces satisfactory sedation in children between 2 and 12-yr-of-age. Behavior of the children at parental separation and at induction of anesthesia was comparable to those who received oral midazolam premedication.

AMBULATORY ANESTHESIOLOGY:Back

Jin Gu Kang, Jin Kyoung Kim, Han-Sin Jeong, Soo-Chan Jung, Moon Hee Ko, Shin Hong Park, Jae Keun Cho, Gil Joon Lee, Ji Won Choi, and Byung Dal Lee

Anesth Analg 2008 106: 1723-1727. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We evaluated the impact of anesthetics on salivary excretion with respect to obtaining a clear surgical field during laryngeal surgery. We found that salivary excretion under propofol/remifentanil anesthesia is greater than under sevoflurane anesthesia.

Ali Movafegh, Reza Alizadeh, Fatimah Hajimohamadi, Fatimah Esfehani, and Mohmad Nejatfar

Anesth Analg 2008 106: 1728-1732. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This study demonstrates that in the outpatient population, oral premedication with Passiflora incarnata reduces preoperative anxiety.

Mukadder Orhan-Sungur, Peter Kranke, Daniel Sessler, and Christian C. Apfel

Anesth Analg 2008 106: 1733-1738. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This quantitative systematic review of all published outcomes studies and abstracts demonstrates that perioperative supplemental oxygen does not reduce the incidence of postoperative nausea and vomiting.

ANESTHETIC PHARMACOLOGY:Back

Burcu Tufanogullari, Paul F. White, Mariana P. Peixoto, Daniel Kianpour, Thomas Lacour, James Griffin, Gary Skrivanek, Amy Macaluso, Mary Shah, and David A. Provost

Anesth Analg 2008 106: 1741-1748. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This placebo-controlled dose-ranging study found that dexmedetomidine infusion rates from 0.2 to 0.8 {micro}g {middle dot} kg-1 {middle dot} h-1 reduced the volatile anesthetic requirement and the need for opioid analgesics and antiemetics in the early postoperative period. Although adjunctive use of dexmedetomidine facilitated early recovery (e.g., postanesthesia care unit stay), it failed to improve later recovery end-points (e.g., hospital discharge, recovery of bowel function).

Johannes Wacker, Eliana Lucchinetti, Marina Jamnicki, José Aguirre, Luc Härter, Marius Keel, and Michael Zaugg

Anesth Analg 2008 106: 1749-1758. [Abstract] [Full Text] [PDF] [Data Supplement]   

IMPLICATIONS: In this human crossover study, we demonstrated for the first time that inhaling sevoflurane at low subanesthetic doses (<1 vol % end-tidal) inhibits agonist-induced detrimental granulocyte-platelet aggregation 24 h later and further attenuates thrombus formation.

Aubrey Yao, JongBun Kim, Richard Atherley, Steven L. Jinks, Earl Carstens, Sean Shargh, Alana Sulger, and Joseph F. Antognini

Anesth Analg 2008 106: 1759-1764. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: In intact rats, depression of dorsal horn neurons responses to noxious stimulation by peri-MAC increases in fluorinated aromatic anesthetics correlate directly with the capacity of these anesthetics to block N-methyl-d-aspartate (NMDA) receptors. Similarly, in decerebrate rats, the aromatic compound with stronger in vitro blocking actions (benzene) produces a much greater depression of responses to nociceptive stimulation than the compound with relatively weak blocking actions (hexafluorobenzene). These data suggest that depression of NMDA receptors underlies depression of dorsal horn neuronal responses to noxious stimulation in the peri-MAC range. Gamma-aminobutyric acid type A (GABAA) receptors may have a supraspinal facilitatory effect.

Motohiko Hanazaki, Masataka Yokoyama, Kiyoshi Morita, Atsushi Kohjitani, Hiroyasu Sakai, Yoshihiko Chiba, and Miwa Misawa

Anesth Analg 2008 106: 1765-1771. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Rho-kinase inhibitors augment the inhibitory effect of propofol in airway smooth muscle contraction.

Avery Tung, Stacy Herrera, Casimir A. Fornal, and Barry L. Jacobs

Anesth Analg 2008 106: 1772-1777. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: New neuron production in adults may play a role in learning and memory. We found no effect of isoflurane, ketamine, propofol, or dexmedetomidine anesthesia on hippocampal cell proliferation in rats. These results suggest that anesthetic effects on cell proliferation are unlikely to play a role in postoperative cognitive changes.

Laurentius J.A. Rampaart, Jeroen P. Beekwilder, Gertrudis Th.H. van Kempen, Rutgeris J. van den Berg, and Dirk L. Ypey

Anesth Analg 2008 106: 1778-1783. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Butamben (n-butyl-p-aminobenzoate), an experimental long-acting epidural local anesthetic in the treatment of chronic pain, inhibits the total barium current through expressed calcium channel types in PC12 cells, including Cav1.2/L-type channels. Because Cav1.2 channels may also occur in human nociceptive C fibers, this result allows the possibility that these L-type channels are involved in the analgesic action of butamben.

Tina C. Sichrovsky, Suneet Mittal, and Jonathan S. Steinberg
(Case Report)
Anesth Analg 2008 106: 1784-1786. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Dexmedetomidine is usually well tolerated, with easily reversible side effects. However, a small percentage of patients seem to develop severe and refractory cardiovascular complications. In an effort to alert other physicians to use caution when administering dexmedetomidine, we report the death of a patient during an electrophysiologic procedure.

TECHNOLOGY, COMPUTING AND SIMULATION:Back

Penelope M. Sanderson, Marcus O. Watson, Walter John Russell, Simon Jenkins, David Liu, Norris Green, Kristen Llewelyn, Phil Cole, Vivian Shek, and Stas S. Krupenia

Anesth Analg 2008 106: 1787-1797. [Abstract] [Full Text] [PDF] [Video Loops] [Data Supplement]   

IMPLICATIONS: Study tests whether auditory displays or head-mounted displays in combination with standard patient monitoring displays help distracted anesthesiologistsv to detect clinically significant events in simulated patients. Anesthesiologists were more likely to detect clinically significant events only when auditory displays were present.

Lyndon Siu, Adam Tucker, Shashi Kanth Manikappa, and John Monagle

Anesth Analg 2008 106: 1798-1802. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: When using the USCOM1A Ultrasonic Cardiac Output Monitor to assess cardiac output, the sitting position should be avoided because it is difficult to obtain a reliable signal in this position. The supine, Trendelenburg, left lateral tilt (20 degrees), and right lateral tilt (20 degrees) positions were comparable with regards to signal acquisition and quality.

Federico Osorio, Mauricio Perilla, D. John Doyle, and J. Martin Palomo
(Technical Communication)
Anesth Analg 2008 106: 1803-1807. [Abstract] [Full Text] [PDF] [Data Supplement]   

IMPLICATIONS: Cone beam computed tomography imaging technology offers the potential to be a tool for clinical airway assessment by providing two- and three-dimensional images of airway structures that may easily be navigated and manipulated using ordinary personal computers.

CTITICAL CARE AND TRAUMA:Back

Danny M. Takanishi, Mihae Yu, Fedor Lurie, Elisabeth Biuk-Aghai, Hideko Yamauchi, Hao Chih Ho, and Alyssa D. Chapital

Anesth Analg 2008 106: 1808-1812. [Abstract] [Full Text] [PDF] [CME]  

IMPLICATIONS: The peripheral blood hematocrit assayed in the clinical laboratory may not provide an accurate estimate of red blood cell volume in critically ill surgical patients. Measurement of plasma volume and red blood cell volume may provide a more accurate guide for blood transfusion requirements.

CRITICAL CARE AND TRAUMA:Back

Stepani Bendel, Sari Karlsson, Ville Pettilä, Pekka Loisa, Marjut Varpula, Esko Ruokonen For the Finnsepsis Study Group

Anesth Analg 2008 106: 1813-1819. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Calculated free cortisol concentrations correlate well with total cortisol concentration, and free cortisol calculation does not predict unfavorable outcome better than total cortisol levels. Clinically, calculation of free cortisol does not help to identify patients who would benefit from corticoid treatment in severe sepsis and septic shock.

Sari Karlsson, Ville Pettilä, Jyrki Tenhunen, Vesa Lund, Seppo Hovilehto, Esko Ruokonen For the Finnsepsis Study Group

Anesth Analg 2008 106: 1820-1826. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Serum vascular endothelial growth factor (VEGF) concentrations are increased in patients with severe sepsis. Although nonsurvivors have significantly lower levels than patients with better outcome, VEGF concentrations do not predict hospital mortality.

OBSTETRIC ANESTHESIOLOGY:Back

Kyung Y. Yoo, Cheol W. Jeong, Myung W. Kang, Seok J. Kim, Sung T. Chung, Min H. Shin, and JongUn Lee

Anesth Analg 2008 106: 1827-1832. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Intraoperative bispectral index values during 1% sevoflurane/50% nitrous oxide general anesthesia were lower, and postoperative analgesic consumption was reduced, in women with prior labor undergoing cesarean delivery compared with women without prior labor.

German E. Luzardo, Rachel A. Karlnoski, Brooke Williams, Devanand Mangar, and Enrico M. Camporesi
(Case Report)
Anesth Analg 2008 106: 1833-1836. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Elevated levels of homocysteine are associated with an increased risk for vascular occlusive disease and thromboembolism. The risk may be exacerbated by the administration of nitrous oxide. This case report discusses the anesthetic management of pregnant patients with hyperhomocysteinemia, including anticoagulation and the theoretical risk of using nitrous oxide.

ECONOMICS, EDUCATION, AND POLICY:Back

Ellise Delphin and Melissa Davidson

Anesth Analg 2008 106: 1837-1843. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The Accreditation Council for Graduate Medical Education Outcomes Project has defined six core areas in which competence must be demonstrated by all trainees. Of these, systems-based practice remains difficult for hospital-based subspecialties to teach and assess because of its focus on interfacing with health care systems. We developed an innovative teaching tool method through resident team projects, which were assessed by the impact each project had on the organization and by the success of the implementation and outcome of the educational initiative.

NEUROSURGICAL ANESTHESIOLOGY:Back

Antoine Pianezza, Romain Barthélémy, Vincent Minville, Frédérique Martin, and Michel Faggianelli
(Case Report)
Anesth Analg 2008 106: 1844-1846. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We report a case, which illustrates the difficulty of establishing the diagnosis of migraine with atypical aura in the perioperative period, when the pathology is unknown by both patient and anesthesiologist. It can lead to inappropriate treatment.

GENERAL ARTICLES:Back

Jesse M. Ehrenfeld, John L. Walsh, and Warren S. Sandberg

Anesth Analg 2008 106: 1847-1852. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We searched our anesthesia information management system database, looking for differences in oxygenation, ventilation and airway pressures between right- and left-sided double-lumen tubes when used by thoracic subspecialty anesthesiologists. By these criteria, the performance of right- and left-sided Mallinckrodt tubes was indistinguishable.

Yun Wang, Adrian W. Gelb, and Yun Yue
The Chinese Society of Anesthesiology: 2007 Annual Meeting Report (Meeting Report)
Anesth Analg 2008 106: 1853-1854. [Full Text] [PDF]  

ANALGESIA:Back

Jérome Zakine, David Samarcq, Emmanuel Lorne, Mona Moubarak, Philippe Montravers, Sadek Beloucif, and Hervé Dupont

Anesth Analg 2008 106: 1856-1861. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Low doses of ketamine improve postoperative analgesia, but the optimal duration of ketamine administration is still unclear. This study demonstrated that postoperative pain and morphine consumption are reduced when ketamine administration is continued for 48 h postoperatively. No side effect due to ketamine administration was observed.

Feikje Wesseldijk, Durk Fekkes, Frank J. Huygen, Elly Bogaerts-Taal, and Freek J. Zijlstra

Anesth Analg 2008 106: 1862-1867. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Plasma levels of serotonin (5-HT) are markedly elevated in complex regional pain syndrome 1 (CRPS1) patients. However, because of the lack of correlations with distinct disease characteristics, 5-HT is probably one of a number of mediators in CRPS1.

Michael J. Sheen, Shung-Tai Ho, Chian-Her Lee, Yu-Chi Tsung, and Fang-Lin Chang

Anesth Analg 2008 106: 1868-1872. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Preoperative gabapentin 1200 mg decreased the incidence and severity of intrathecal morphine-induced pruritus and can be a clinically important adjunct both for its analgesic and antipruritic effects.

Hong Xie, James H. Woods, John R. Traynor, and Mei-Chuan Ko

Anesth Analg 2008 106: 1873-1881. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Using pharmacological approaches, this study elucidates the efficacy and receptor binding selectivity of endomorphin-1 and -2 in the spinal cord and thalamus of rats. Both behavioral and G protein functional studies together demonstrate that intrathecal administration of endomorphins produced partial agonist actions selectively at spinal {micro}-opioid receptors.

Emmanuel Guntz, Hélène Dumont, Els Pastijn, Alban de Kerchove d’Exaerde, Karima Azdad, Maurice Sosnowski, Serge N. Schiffmann, and David Gall

Anesth Analg 2008 106: 1882-1889. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This study shows that A2A receptors are present inside the dorsal horn of the spinal cord on a sample of neurons from the substantia gelatinosa and that activation of these receptors inhibits the N-methyl-d-aspartate receptor activity. Therefore, adenosine could exert, through the activation of A2A receptors, a control of the wind-up phenomenon and consequently of hyperalgesia.

Rita Marincsák, Balázs I. Tóth, Gabriella Czifra, Tamás Szabó, László Kovács, and Tamás Bíró

Anesth Analg 2008 106: 1890-1896. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We investigated the possible involvement of transient receptor potential vanilloid-1 (TRPV1) in the analgesic action of tramadol. We found that tramadol acts as an agonist of TRPV1. Our presented findings may equally explain both the desired analgesic as well as the often-seen, yet "unexpected," local side effects (e.g. initiation of burning pain and erythema) of tramadol.

Radica M. Stepanovic-Petrovic, Maja A. Tomic, Sonja M. Vuckovic, Sonja Paranos, Nenad D. Ugresic, Milica S. Prostran, Slobodan Milovanovic, and Bogdan Boskovic

Anesth Analg 2008 106: 1897-1903. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: The anticonvulsants oxcarbazepine, gabapentin, and topiramate are effective analgesics in a writhing model of visceral pain in the mouse.

Sahoko Koyanagi, Shugaku Himukashi, Kumiko Mukaida, Tsutomu Shichino, and Kazuhiko Fukuda

Anesth Analg 2008 106: 1904-1909. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: We demonstrated that nitrous oxide activated mesolimbic dopaminergic neurons and that the antinociceptive effect of nitrous oxide was attenuated by a dopamine D2-like receptor antagonist. These results suggest that the mesolimbic dopaminergic system is involved in the antinociceptive effect of nitrous oxide.

Axel R. Sauter, Michael S. Dodgson, Audun Stubhaug, Anne Marie Halstensen, and Øivind Klaastad

Anesth Analg 2008 106: 1910-1915. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: Similar success is obtained using either nerve stimulation or ultrasound guidance during lateral sagittal infraclavicular block. Local anesthetic injection cranioposterior to the artery appears feasible using ultrasound guidance.

Jacques T. YaDeau, Vincent R. LaSala, Leonardo Paroli, Richard L. Kahn, Kethy M. Jules-Elysée, David S. Levine, Barbara L. Wukovits, and Jane Y. Lipnitsky

Anesth Analg 2008 106: 1916-1920. [Abstract] [Full Text] [PDF]  

IMPLICATIONS: This randomized, double-blind, placebo-controlled trial examined the effect of adding clonidine to bupivacaine for popliteal fossa nerve blockade. Patients received placebo, intramuscular clonidine, or clonidine added to bupivacaine (n = 33 per group). Clonidine, when included with the local anesthetic, significantly prolonged analgesia by 3-4 h.

LETTERS TO THE EDITOR:Back

David Wax
The Wild Wild Web
Anesth Analg 2008 106: 1921. [Full Text] [PDF]  

Peter S. A. Glass and Paul F. White
The Wild Wild Web
Anesth Analg 2008 106: 1921. [Full Text] [PDF]  

Barry L. Friedberg
Avoiding Emetogenic Triggers in the First Place Is More Effective than Using Antiemetics
Anesth Analg 2008 106: 1921-1922. [Full Text] [PDF]  

Tong J. Gan, T. Meyer, C. C. Apfel, F. Chung, P. J. Davis, A. S. Habib, V. Hooper, A. Kovac, P. Kranke, P. Myles, B. Philip, G. Samsa, D. I. Sessler, J. Temo, M. R. Tramèr, C. Vander Kolk, and M. Watcha
Avoiding Emetogenic Triggers in the First Place Is More Effective than Using Antiemetics
Anesth Analg 2008 106: 1922. [Full Text] [PDF]  

Christian Dürsteler, Anna Mases, and Margarita M. Puig
Universal PONV Prophylaxis in General Anesthesia: Should We Consider Its Immediate Implementation?
Anesth Analg 2008 106: 1922. [Full Text] [PDF]  

Paul F. White and Peter S. A. Glass
Universal PONV Prophylaxis in General Anesthesia: Should We Consider Its Immediate Implementation?
Anesth Analg 2008 106: 1922-1923. [Full Text] [PDF]  

Jeffrey L. Tong and Livia S. Malanjum
Reducing Epistaxis During Nasotracheal Intubation
Anesth Analg 2008 106: 1923-1924. [Full Text] [PDF]  

Jae-Hyon Bahk and Kwang Suk Seo
Reducing Epistaxis During Nasotracheal Intubation
Anesth Analg 2008 106: 1924. [Full Text] [PDF]  

Jacek B. Cywinski, Andrew Zura, and D. John Doyle
Unexpected Obstruction of a Parker Flex-TipTM Tracheal Tube in a Patient with Subglottic Stenosis
Anesth Analg 2008 106: 1924. [Full Text] [PDF]  

Jeffrey D. Parker
Unexpected Obstruction of a Parker Flex-TipTM Tracheal Tube in a Patient with Subglottic Stenosis
Anesth Analg 2008 106: 1924-1925. [Full Text] [PDF]  

Jeffrey L. Tong
Smaller Is Better Through the Nose
Anesth Analg 2008 106: 1925. [Full Text] [PDF]  

Kazuna Sugiyama and Koki Okushima
Smaller Is Better Through the Nose
Anesth Analg 2008 106: 1925-1926. [Full Text] [PDF]  

Paul S. Pagel
Additive Cardioprotection by Ethanol and Sevoflurane: Are Sarcolemmal KATP Channels Also Involved?
Anesth Analg 2008 106: 1926. [Full Text] [PDF]  

Masami Miyamae, Shingo Sugioka, and Vincent M. Figueredo
Additive Cardioprotection by Ethanol and Sevoflurane: Are Sarcolemmal KATP Channels Also Involved?
Anesth Analg 2008 106: 1926-1927. [Full Text] [PDF]  

Yoshi Misonoo, Kiyoshi Moriyama, Tatsuya Yamada, Itsuo Nakatsuka, and Junzo Takeda
Nasotracheal Intubation with a 32F Blue Line Endobroncheal Tube®
Anesth Analg 2008 106: 1927. [Full Text] [PDF]  

Vijay Tarnal, Matthew Molyneux, and Kevin Tremper
Increasing the Likelihood of Successful Insertion of "Laser Tubes" in Patients with a Known Difficult Airway
Anesth Analg 2008 106: 1927-1928. [Full Text] [PDF]  

Ian M. Randall, Joseph Costello, and Jose C. A. Carvalho
Transversus Abdominis Plane Block in a Patient with Debilitating Pain from an Abdominal Wall Hematoma Following Cesarean Delivery
Anesth Analg 2008 106: 1928. [Full Text] [PDF]  

Carlo Pancaro, Tonya Miller, and R. Scott Dingeman
Anesthetic Management of a Child with Bannayan-Riley-Ruvalcaba Syndrome
Anesth Analg 2008 106: 1928-1929. [Full Text] [PDF]  

BOOK AND MULTIMEDIA REVIEWS:Back

Francois J. Archambault and Sandra Morris
Cardiopulmonary Bypass: Principles and Practice, 3rd ed.
Anesth Analg 2008 106: 1930-1931. [Full Text] [PDF]  

Robert S. Holzman
Management of the Difficult and Failed Airway
Anesth Analg 2008 106: 1931. [Full Text] [PDF]  

Jovan Popovic
Atlas of Ultrasound and Nerve Stimulation-Guided Regional Anesthesia
Anesth Analg 2008 106: 1931-1932. [Full Text] [PDF]  

James L. Helstrom
Perioperative Medicine: Managing for Outcome
Anesth Analg 2008 106: 1932-1933. [Full Text] [PDF]  

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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
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