EDITORIALS:

Karen Gelb and Adrian W. Gelb

Sex and Gender in the Perioperative Period: Wake Up to Reality
Anesth Analg 2008 107: 1-3. [Full Text] [PDF] [Request Permissions]  

May L. Chin and Richard Rosenquist

Sex, Gender, and Pain: "Men Are from Mars, Women Are from Venus ..."
Anesth Analg 2008 107: 4-5. [Full Text] [PDF] [Request Permissions]  

Paul F. White

Red-Hot Chili Peppers: A Spicy New Approach to Preventing Postoperative Pain
Anesth Analg 2008 107: 6-8. [Full Text] [PDF] [Request Permissions]  

Steven L. Shafer and Michel M. R. F. Struys

Mixed Effect Modeling in Analgesia Trials
Anesth Analg 2008 107: 9-10. [Full Text] [PDF] [Request Permissions]  

Sorin J. Brull, Mohamed Naguib, and Ronald D. Miller

Residual Neuromuscular Block: Rediscovering the Obvious
Anesth Analg 2008 107: 11-14. [Full Text] [PDF] [Request Permissions]  

Elliot J. Krane

Patient-Controlled Analgesia: Proxy-Controlled Analgesia?
Anesth Analg 2008 107: 15-17. [Full Text] [PDF] [Request Permissions]  

CARDIOVASCULAR ANESTHESIOLOGY:

Charles W. Hogue, Jr, Robert Fucetola, Tamara Hershey, Abullah Nassief, Stanley Birge, Victor G. Dávila-Román, Benico Barzilai, Betsy Thomas, Kenneth B. Schechtman, and Kenneth Freedland

The Role of Postoperative Neurocognitive Dysfunction on Quality of Life for Postmenopausal Women 6 Months After Cardiac Surgery
Anesth Analg 2008 107: 21-28. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In postmenopausal women undergoing cardiac surgery, a neurocognitive deficit 4 to 6 wk after surgery was associated with postoperative impairment in physical components of quality of life and independent activities of daily living. Some aspects of quality of life in postmenopausal women may not be amenable to improvements with cardiac surgery.

Amanda A. Fox

Pro: Newly Appreciated Pathophysiology of Ischemic Heart Disease in Women Mandates Changes in Perioperative Management (Editorial)
Anesth Analg 2008 107: 29-32. [Full Text] [PDF] [Request Permissions]  

Colleen Gorman Koch

Con: Newly Appreciated Pathophysiology of Ischemic Heart Disease in Women Mandates Changes in Perioperative Management (Editorial)
Anesth Analg 2008 107: 33-36. [Full Text] [PDF] [Request Permissions]  

Robina Matyal

Newly Appreciated Pathophysiology of Ischemic Heart Disease in Women Mandates Changes in Perioperative Management: A Core Review (Review Article)
Anesth Analg 2008 107: 37-50. [Abstract] [Full Text] [PDF] [Request Permissions]  

Patrick Lecomte, Luc Foubert, Frank Nobels, José Coddens, Guy Nollet, Filip Casselman, Paul Van Crombrugge, Geert Vandenbroucke, and Guy Cammu

Dynamic Tight Glycemic Control During and After Cardiac Surgery Is Effective, Feasible, and Safe
Anesth Analg 2008 107: 51-58. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We validated a dynamic insulin regimen to control intraoperative and postoperative blood glucose levels in nondiabetic and diabetic cardiac surgical patients. The Aalst Glycemia Insulin Protocol was effective for maintaining perioperative glycemic control (80-110 mg/dL) with a very low incidence of hypoglycemia (<60 mg/dL).

Neil Singla, David C. Warltier, Sweeta D. Gandhi, Philip D. Lumb, Robert N. Sladen, Solomon Aronson, Mark F. Newman, Howard L. Corwin for the ESCAPE-2 Study Group

Treatment of Acute Postoperative Hypertension in Cardiac Surgery Patients: An Efficacy Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery-2 (ESCAPE-2), a Randomized, Double-Blind, Placebo-Controlled Trial
Anesth Analg 2008 107: 59-67. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Clevidipine is effective and well tolerated in the IV treatment of acute hypertension after cardiac surgery. It demonstrates rapid onset, selective arterial dilation, and titratable blood pressure-decreasing effect.

PEDIATRIC ANESTHESIOLOGY:

Terri Voepel-Lewis, Annette Marinkovic, Amy Kostrzewa, Alan R. Tait, and Shobha Malviya

The Prevalence of and Risk Factors for Adverse Events in Children Receiving Patient-Controlled Analgesia by Proxy or Patient-Controlled Analgesia After Surgery
Anesth Analg 2008 107: 70-75. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study describes the prevalence of and risk factors for adverse events in children receiving patient-controlled analgesia by proxy (PCA-P) and PCA. A significant number of children receiving these therapies experience clinically significant events, warranting close monitoring throughout the use of PCA-P and PCA.

AMBULATORY ANESTHESIOLOGY:

Peter Szmuk, Nimrod Aroyo, Tiberiu Ezri, Gleb Muzikant, Marian Weisenberg, and Daniel I. Sessler

Listening to Music During Anesthesia Does Not Reduce the Sevoflurane Concentration Needed to Maintain a Constant Bispectral Index
Anesth Analg 2008 107: 77-80. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The partial pressure of sevoflurane required to maintain the bispectral index near 50 during laparoscopic surgery was identical in patients exposed to intraoperative music and in those not exposed to music. Previous work suggests that music reduces preoperative stress and may be useful when providing sedation; however, our results do not support the use of music during surgery.

ANESTHETIC PHARMACOLOGY:

Albert Dahan, Benjamin Kest, Amanda R. Waxman, and Elise Sarton

Sex-Specific Responses to Opiates: Animal and Human Studies (Review Article)
Anesth Analg 2008 107: 83-95. [Abstract] [Full Text] [PDF] [Request Permissions]  

Tatsushi Yoshitomi, Atsushi Kohjitani, Shigeru Maeda, Hitoshi Higuchi, Masahiko Shimada, and Takuya Miyawaki

Dexmedetomidine Enhances the Local Anesthetic Action of Lidocaine via an -2A Adrenoceptor (Review Article)
Anesth Analg 2008 107: 96-101. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The present study demonstrated that dexmedetomidine and other {alpha}-2 adrenoceptor agonists enhanced the local anesthetic action of lidocaine at the periphery. Thus, they have potential as a new adjunct to local anesthetics and may increase the reliability and efficacy of regional anesthesia.

Philipp-Alexander Brand, Andrea Paris, Berthold Bein, Patrick Meybohm, Jens Scholz, Henning Ohnesorge, and Peter H. Tonner

Propofol Sedation Is Reduced by 9-Tetrahydrocannabinol in Mice (Review Article)
Anesth Analg 2008 107: 102-106. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: It has been reported that propofol increases cerebral endocannabinoid concentrations. We found that the sedative effect of a low propofol concentration was abolished by 50 mg/kg delta9-tetrahydrocannabinol (D9-THC) that produced no sedation when given alone. Our results indicate a dose-dependent antagonistic interaction between D9-THC and propofol.

Maria Wittmann, Thomas Schaaf, Ineke Peters, Stefan Wirz, Bernd W. Urban, and Martin Barann

The Effects of Fentanyl-Like Opioids and Hydromorphone on Human 5-HT_3A Receptors (Review Article)
Anesth Analg 2008 107: 107-112. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We found strong evidence that morphine and hydromorphone, in contrast to fentanyl type opioids, specifically interact with human 5-HT3A receptors. Since 5-HT3 receptors are involved in the mediation of emesis, future clinical studies could test whether corresponding differences in emetogenicity will be found.

Philippe Dulvadestin, Alain Gilton, Philippe Hernigou, and Jean Marty

The Onset Time of Atracurium Is Prolonged in Patients with Sickle Cell Disease (Brief Report)
Anesth Analg 2008 107: 113-116. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In patients with sickle cell disease, onset of the neuromuscular blocking effect of atracurium is prolonged but the duration of action is unchanged. Neuromuscular monitoring may guide the time of laryngoscopy in these patients.

TECHNOLOGY, COMPUTING, AND STIMULATION:

Benno Rehberg, Christiane Ryll, Daniel Hadzidiakos, Falk v. Dincklage, and Jan H. Baars

Variability Comparison of the Composite Auditory Evoked Potential Index and the Bispectral Index During Propofol-Fentanyl Anesthesia
Anesth Analg 2008 107: 117-124. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: At steady concentrations of propofol, bispectral index (BIS) exhibits less variability than AAI1.6. BIS shows a better agreement to the concentration of propofol, whereas the AAI1.6 may detect recovery of consciousness more accurately than the BIS.

Serafina Lacerenza, Maria Pia De Carolis, Francesca Paola Fusco, Giuseppe La Torre, Giacomina Chiaradia, and Costantino Romagnoli

An Evaluation of a New Combined Spo₂/PtcCO₂ Sensor in Very Low Birth Weight Infants (Technical Communication)
Anesth Analg 2008 107: 125-129. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: TOSCA, a new combined pulse oximetry and transcutaneous Pco2 sensor, is easy to use and safe for very low birth weight infants. The pulse oximeter measurements may be useful for titrating oxygen therapy. Pco2 measurement is most useful as a trend monitor and independent confirmation of arterial Pco2 is required if an accurate value is needed.

PATIENT SAFETY:

Glenn S. Murphy, Joseph W. Szokol, Jesse H. Marymont, Steven B. Greenberg, Michael J. Avram, and Jeffery S. Vender

Residual Neuromuscular Blockade and Critical Respiratory Events in the Postanesthesia Care Unit
Anesth Analg 2008 107: 130-137. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Residual neuromuscular blockade may contribute to adverse respiratory outcomes in the postanesthesia care unit. In this investigation, we observed evidence of incomplete neuromuscular recovery in the majority of patients with critical respiratory events after general anesthesia.

Shireen Ahmad, Alexander Nagle, Robert J. McCarthy, Paul C. Fitzgerald, John T. Sullivan, and Jay Prystowsky

Postoperative Hypoxemia in Morbidly Obese Patients With and Without Obstructive Sleep Apnea Undergoing Laparoscopic Bariatric Surgery
Anesth Analg 2008 107: 138-143. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Morbidly obese subjects with and without obstructive sleep apnea, experienced significant episodic hypoxemia after laparoscopic bariatric surgery. Obstructive sleep apnea did not increase the incidence or the severity of the hypoxemic episodes.

Philip M. Jones, Kevin P. Armstrong, Paidrig M. Armstrong, Richard A. Cherry, Christopher C. Harle, Jason Hoogstra, and Timothy P. Turkstra

A Comparison of GlideScope® Videolaryngoscopy to Direct Laryngoscopy for Nasotracheal Intubation
Anesth Analg 2008 107: 144-148. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: A prospective, randomized, blinded, clinical trial was conducted to assess the effectiveness of the GlideScope for nasotracheal intubation. When compared with direct laryngoscopy, GlideScope videolaryngoscopy was faster, easier, and resulted in a much lower incidence of sore throat postoperatively.

Bruce W. Fisher, Gillian Ramsay, Sumit R. Majumdar, Chantelle T. Hrazdil, Barry A. Finegan, Rajdeep S. Padwal, and Finlay A. McAlister

The Ankle-to-Arm Blood Pressure Index Predicts Risk of Cardiac Complications After Noncardiac Surgery
Anesth Analg 2008 107: 149-154. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Beyond traditional preoperative cardiac risk stratification using the revised cardiac risk index, we determined that the presence of peripheral arterial disease, detected by an abnormally low ankle-to-arm blood pressure index (AAI), is an independent predictor for perioperative cardiac events in patients undergoing noncardiac surgery.

Bertrand Prunet, Eric Meaudre, Ambroise Montcriol, Yves Asencio, Julien Bordes, Guillaume Lacroix, and Eric Kaiser

A Prospective Randomized Trial of Two Safety Peripheral Intravenous Catheters
Anesth Analg 2008 107: 155-158. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Whether the security system is active or passive, safety IV catheters do not have a greater incidence of placement failure than standard catheters. Users feel better protected, but find their use more difficult, and their handling generates more splashing of blood into the environment.

CRITICAL CARE AND TRAUMA:

Raghavan Raju and Irshad H. Chaudry

Sex Steroids/Receptor Antagonist: Their Use as Adjuncts After Trauma-Hemorrhage for Improving Immune/Cardiovascular Responses and for Decreasing Mortality from Subsequent Sepsis (Review Article)
Anesth Analg 2008 107: 159-166. [Abstract] [Full Text] [PDF] [Request Permissions]  

Shinji Akada, Shinhiro Takeda, Yuko Yoshida, Keiko Nakazato, Masaki Mori, Takashi Hongo, Keiji Tanaka, and Atsuhiro Sakamoto

The Efficacy of Dexmedetomidine in Patients with Noninvasive Ventilation: A Preliminary Study (Brief Report)
Anesth Analg 2008 107: 167-170. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Dexmedetomidine is an effective sedative drug for patients in whom noninvasive ventilation is difficult because of agitation.

OBSTETRIC ANESTHESIOLOGY:

Rachel Farragher, Chrisen H. Maharaj, Brendan D. Higgins, Sharon Crowe, Padvaic Burke, Christopher D. Laffey, Noel M. Flynn, and John G. Laffey

Sevoflurane and the Feto-Placental Vasculature: The Role of Nitric Oxide and Vasoactive Eicosanoids
Anesth Analg 2008 107: 171-177. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Sevoflurane dose-dependently dilates the feto-placental vasculature by a mechanism mediated in part via the lipoxygenase pathway and independent of nitric oxide and the cyclooxygenase pathway.

ECONOMICS, EDUCATION, AND POLICY:

Cynthia A. Wong and Marie Christine Stock

The Status of Women in Academic Anesthesiology: A Progress Report
Anesth Analg 2008 107: 178-184. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The percentage of anesthesiology faculty members who are women has increased over the past two decades, as has the number of women who are department chairs and women in leadership positions in anesthesiology subspecialty and academic societies. However, women remain markedly under-represented at the full professor level, and the rate of increase in women in academic anesthesiology lags behind the increase in women who are medical students and anesthesiology residents.

Michael M. Vigoda, Luis I. Rodríguez, Eric Wu, Kevin Perry, Robert Duncan, David J. Birnbach, and David A. Lubarsky

The Use of an Anesthesia Information System to Identify and Trend Gender Disparities in Outpatient Medical Management of Patients with Coronary Artery Disease
Anesth Analg 2008 107: 185-192. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Anesthesia information management systems can be used to aggregate preoperative data to provide an epidemiological snapshot of outpatient community care. At our hospital, there was a significant gender disparity in preoperative use of {beta}-blockers, statins, and aspirin in patients with coronary artery disease undergoing elective noncardiac surgery.

NEUROSURGICAL ANESTHESIOLOGY:

Lars Peter Wang and Michael James Paech

Neuroanesthesia for the Pregnant Woman (Review Article)
Anesth Analg 2008 107: 193-200. [Abstract] [Full Text] [PDF] [Request Permissions]  

Kamila Vagnerova, Ines P. Koerner, and Patricia D. Hurn

Gender and the Injured Brain (Review Article)
Anesth Analg 2008 107: 201-214. [Abstract] [Full Text] [PDF] [Request Permissions]  

Hironobu Hayashi, Masahiko Kawaguchi, Yuri Yamamoto, Satoki Inoue, Munehisa Koizumi, Yurito Ueda, Yoshinori Takakura, and Hitoshi Furuya

The Application of Tetanic Stimulation of the Unilateral Tibial Nerve Before Transcranial Stimulation Can Augment the Amplitudes of Myogenic Motor-Evoked Potentials from the Muscles in the Bilateral Upper and Lower Limbs (Review Article)
Anesth Analg 2008 107: 215-220. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Because myogenic motor-evoked potentials (MEPs) are very sensitive to suppression by anesthetic and neuromuscular blocking drugs, the techniques to augment MEP responses are desirable under anesthesia. We report that the application of tetanic stimulation to the left tibial nerve before transcranial stimulation augmented the amplitudes of MEPs from the muscles without tetanic nerve stimulation and those with tetanic nerve stimulation.

Michal Barak, Majed Kabha, Doron Norman, Michael Soudry, Yeshayahu Kats, and Simcha Milo

Cerebral Microemboli During Hip Fracture Fixation: A Prospective Study (Review Article)
Anesth Analg 2008 107: 221-225. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This is a prospective study of 22 patients who underwent hip fracture fixation surgery. Using transcranial Doppler during the surgery, signals of solid and gas microemboli in the cerebral circulation were detected in nine of these patients.

Randal S. Blank, Christine S. Waldrop, and Philip J. Balestrieri

Pseudomeningocele: An Unusual Cause of Intraoperative Tracheal Compression and Expiratory Obstruction (Case Report)
Anesth Analg 2008 107: 226-228. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Pseudomeningocele, a cerebrospinal fluid collection, which can occur after spine surgery, may result in life-threatening airway compromise intraoperatively.

Adam K. Jacob, John A. Dilger, and James R. Hebl

Status Epilepticus and Intrathecal Fluorescein: Anesthesia Providers Beware (Case Report)
Anesth Analg 2008 107: 229-231. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Intrathecal fluorescein is sometimes used to facilitate the diagnosis and localization of cerebrospinal fluid leaks. We report a case of status epilepticus after intrathecal administration of fluorescein. Anesthesia providers should be aware of complications associated with intrathecal fluorescein use and be prepared to manage neurologic complications during the perioperative period.

GENERAL ARTICLES:

Marie Csete

Gender Issues in Transplantation (Special Article)
Anesth Analg 2008 107: 232-238. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Gender issues affect all aspects of transplantation, including diagnoses leading to transplantation, willingness to be a living donor, access to transplantation, and transplant outcomes.

Michael P. Hutchens, Jennifer Dunlap, Patricia D. Hurn, and Per O. Jarnberg

Renal Ischemia: Does Sex Matter? (Review Article)
Anesth Analg 2008 107: 239-249. [Abstract] [Full Text] [PDF] [Request Permissions]  

2007–2008 Editorial Board, Anesthesia & Analgesia

2008 Anesthesia & Analgesia Guide for Authors (Special Article)
Anesth Analg 2008 107: 250-263. [Full Text] [PDF] [Request Permissions]  

Necmiye Hadimioglu, Iman Saadawy, Tayyup Saglam, Zeki Ertug, and Ayhan Dinckan

The Effect of Different Crystalloid Solutions on Acid-Base Balance and Early Kidney Function After Kidney Transplantation
Anesth Analg 2008 107: 264-269. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Normal saline, Ringer's lactate and Plasmalyte solutions can be safely used during uncomplicated, short-duration renal transplants; however, the best metabolic profile is maintained in patients who receive Plasmalyte.

PAIN MEDICINE:

Igor Kissin

Vanilloid-Induced Conduction Analgesia: Selective, Dose-Dependent, Long-Lasting, with a Low Level of Potential Neurotoxicity (Special Article)
Anesth Analg 2008 107: 271-281. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Vanilloid agonists (capsaicin, resiniferatoxin) applied to the peripheral nerves provide conduction blockade. In contrast to the analgesic component of conduction anesthesia produced by local anesthetics, vanilloid agonists provide conduction analgesia not associated with suppression of motor or sensory functions not related to pain. The article summarizes data suggesting the clinical applicability of vanilloid-induced conduction analgesia.

Eske K. Aasvang, Jeanette B. Hansen, Jørgen Malmstrøm, Torsten Asmussen, Daniel Gennevois, Michel M. R. F. Struys, and Henrik Kehlet

The Effect of Wound Instillation of a Novel Purified Capsaicin Formulation on Postherniotomy Pain: A Double-Blind, Randomized, Placebo-Controlled Study
Anesth Analg 2008 107: 282-291. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We performed a randomized double-blind study of wound instillation of purified capsaicin versus placebo on postherniotomy pain. Capsaicin-treated patients had significantly less pain during the first 3-4 days postoperatively.

Ahed Zeidan, Rida Kassem, Nazih Nahleh, Hilal Maaliki, Mohamad El-khatib, Michel M.R.F. Struys, and Anis Baraka

Intraarticular Tramadol-Bupivacaine Combination Prolongs the Duration of Postoperative Analgesia After Outpatient Arthroscopic Knee Surgery
Anesth Analg 2008 107: 292-299. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Intraarticular tramadol plus bupivacaine provides a longer duration of analgesia than either drug alone after arthroscopic knee surgery.

Asokumar Buvanendran, Jeffrey S. Kroin, Maruti R. Kari, and Kenneth J. Tuman

A New Knee Surgery Model in Rats to Evaluate Functional Measures of Postoperative Pain
Anesth Analg 2008 107: 300-308. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: With the increase in number of knee surgeries being performed, postoperative analgesic management remains a challenge. The present study uses a new animal knee surgery model to characterize pain-related behavior in the rat, and its alleviation with systemic and intrathecal drug treatment.

PAIN MECHANISMS:

Robert W. Hurley and Meredith C. B. Adams

Sex, Gender, and Pain: An Overview of a Complex Field (Review Article)
Anesth Analg 2008 107: 309-317. [Abstract] [Full Text] [PDF] [Request Permissions]  

Kenji Sugimoto, Igor Kissin, and Gary Strichartz

A High Concentration of Resiniferatoxin Inhibits Ion Channel Function in Clonal Neuroendocrine Cells
Anesth Analg 2008 107: 318-324. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Long-term, selective blockade of nociceptor fibers can be accomplished by resiniferatoxin through a novel, nontoxic mechanism that depresses excitability by reversible internalization of Na+ channels. The fundamental cellular mechanism of this action might be exploited to design other drugs that also provide peripheral analgesia.

REGIONAL ANESTHESIA:

Rose Christopherson, Kenneth E. James, Mara Tableman, Prudence Marshall, and Frank E. Johnson

Long-Term Survival After Colon Cancer Surgery: A Variation Associated with Choice of Anesthesia
Anesth Analg 2008 107: 325-332. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We studied long-term survival after resection of colon cancer in a trial of general anesthesia with and without epidural anesthesia and analgesia supplementation. Epidural anesthesia was associated with improved survival among patients with stage 0-II disease for the first 1.46 years, but a trend toward poorer survival for the next 8.5 years, and no effect on survival of patients with stage III-IV disease.

Asha Tyagi, Anil Kumar, Ashok Kumar Sethi, and Medha Mohta

Epidural Volume Extension and Intrathecal Dose Requirement: Plain Versus Hyperbaric Bupivacaine
Anesth Analg 2008 107: 333-338. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Administered with or without epidural volume extension, plain bupivacaine appears to be more effective requiring a smaller dose and producing a higher sensory block with an earlier onset than to hyperbaric bupivacaine. There is no clinical utility of epidural volume extension application to intrathecal hyperbaric bupivacaine, since it failed to decrease the dose or raise the level of block, when combined spinal epidural was performed in the sitting position.

David A. Burns, Bruce Ben-David, Jacques E. Chelly, and J. Eric Greensmith

Intercostally Placed Paravertebral Catheterization: An Alternative Approach to Continuous Paravertebral Blockade (Brief Report)
Anesth Analg 2008 107: 339-341. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Continuous paravertebral nerve blocks can provide effective postoperative analgesia after abdominal and thoracic surgery. We reviewed the patient-controlled analgesia consumption, pain scores, and complications of 110 patients who received a paravertebral catheter via the intercostal approach and found low narcotic consumption, low pain scores, and no clinically significant complications.

LETTERS TO THE EDITOR:

Jens Lohser and Jay B. Brodsky

Undersizing Left Double-Lumen Tubes
Anesth Analg 2008 107: 342. [Full Text] [PDF] [Request Permissions]  

Steven M. Neustein

What Is the Best Choice for Size of Double Lumen Tube?
Anesth Analg 2008 107: 342-343. [Full Text] [PDF] [Request Permissions]  

George A. Mashour

Etomidate, Nitric Oxide, and Cerebral Vasospasm
Anesth Analg 2008 107: 343. [Full Text] [PDF] [Request Permissions]  

Stephen M. Howell and Richard P. Driver

Etomidate, Nitric Oxide, and Cerebral Vasospasm
Anesth Analg 2008 107: 343-344. [Full Text] [PDF] [Request Permissions]  

Seza Apiliogullari and Ates Duman

Smoking and Nalbuphine May Reduce Postoperative Emesis
Anesth Analg 2008 107: 344. [Full Text] [PDF] [Request Permissions]  

Miriam Harnett and Scott Segal

Smoking and Nalbuphine May Reduce Postoperative Emesis
Anesth Analg 2008 107: 344. [Full Text] [PDF] [Request Permissions]  

Harald V. Genzwuerker and Jochen Hinkelbein

Esophageal Seal Is Not the Only Consideration in Supraglottic Airway Devices
Anesth Analg 2008 107: 344-345. [Full Text] [PDF] [Request Permissions]  

Sven Bercker, Willi Schmidbauer, and Thoralf Kerner

Esophageal Seal Is Not the Only Consideration in Supraglottic Airway Devices
Anesth Analg 2008 107: 345. [Full Text] [PDF] [Request Permissions]  

Hiroshi Inoue, Osamu Honda, and Hiroaki Uchida

Airtraq® as an Intubating Conduit
Anesth Analg 2008 107: 345. [Full Text] [PDF] [Request Permissions]  

Michael J. Sheen and Shung-Tai Ho

Mirtazapine Relieves Postdural Puncture Headache
Anesth Analg 2008 107: 346. [Full Text] [PDF] [Request Permissions]  

Ahmed M. Mukhtar and Gihan Obayah

Esophageal Doppler Monitor: A New Tool in Monitoring Video Assisted Thoracoscopic Surgery for Ligation of Patent Ductus Arteriosus
Anesth Analg 2008 107: 346-347. [Full Text] [PDF] [Request Permissions]  

Akihiro Suzuki, Takayuki Kunisawa, Tomoki Sasakawa, Norifumi Katsumi, Kimimoto Nagashima, and Hiroshi Iwasaki

Unexpected Internal Jugular Vein Obstruction Revealed by Ultrasound Surface Scan Before Central Venous Catheter Insertion
Anesth Analg 2008 107: 347-348. [Full Text] [PDF] [Request Permissions]  

Dario Galante

Transesophageal Doppler Probe and Proseal Laryngeal Mask Airway. A New Technique for Probe Insertion in Pediatric Anesthesia
Anesth Analg 2008 107: 348. [Full Text] [PDF] [Request Permissions]  

BOOK AND MULTIMEDIA REVIEWS:

Brian Egan

Basics of Anesthesia, 5th ed.
Anesth Analg 2008 107: 349. [Full Text] [PDF] [Request Permissions]  

Zaneta Y. Strouch and Mark A. Chaney

Atlas of Intraoperative Transesophageal Echocardiography: Surgical and Radiological Correlations
Anesth Analg 2008 107: 349-350. [Full Text] [PDF] [Request Permissions]  

Sylvia Y. Dolinski

Decision Making in Anesthesiology. 4th ed.
Anesth Analg 2008 107: 350-351. [Full Text] [PDF] [Request Permissions]  

ERRATA:

ERRATUM
Anesth Analg 2008 107: 238. [Full Text] [PDF] [Request Permissions]  

Erratum
Anesth Analg 2008 107: 299. [Full Text] [PDF] [Request Permissions]  

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