EDITORIALS:

Amr E. Abouleish

Productivity-Based Compensations Versus Incentive Plans
Anesth Analg 2008 107: 1765-1767. [Full Text] [PDF] [Request Permissions]  

Paul S. Pagel

Remote Exposure to Xenon Produces Delayed Preconditioning Against Myocardial Infarction In Vivo: Additional Evidence That Noble Gases Are Not Biologically Inert
Anesth Analg 2008 107: 1768-1771. [Full Text] [PDF] [Request Permissions]  

Robert S. Lagasse

The Right Stuff: Veterans Affairs National Surgical Quality Improvement Project
Anesth Analg 2008 107: 1772-1774. [Full Text] [PDF] [Request Permissions]  

Nathan L. Pace

Independent Predictors from Stepwise Logistic Regression May Be Nothing More than Publishable P Values
Anesth Analg 2008 107: 1775-1778. [Full Text] [PDF] [Data Supplement]  [Request Permissions]  

CARDIOVASCULAR ANESTHESIOLOGY:

Klaus Martin, Gunther Wiesner, Tamás Breuer, Rüdiger Lange, and Peter Tassani

The Risks of Aprotinin and Tranexamic Acid in Cardiac Surgery: A One-Year Follow-Up of 1188 Consecutive Patients
Anesth Analg 2008 107: 1783-1790. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Tranexamic acid is associated with complications after valve surgery; aprotinin is coupled with complications after coronary artery bypass graft surgery. One-year mortality is significantly increased after aprotinin administration in patients undergoing high risk cardiac surgery. According to our results, aprotinin should not be used in coronary artery bypass graft and high risk patients, whereas administration of tranexamic acid is not recommended for valvular heart surgery.

Niels Rahe-Meyer, Michael Winterhalter, Julia Hartmann, Albert Pattison, Hartmut Hecker, Andreas Calatzis, and Cristina Solomon

An Evaluation of Cyclooxygenase-1 Inhibition Before Coronary Artery Surgery: Aggregometry Versus Patient Self-Reporting
Anesth Analg 2008 107: 1791-1797. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Aspirin intake before surgery influences cyclooxygenase-1 pathway-dependent platelet function, with controversial effects on perioperative bleeding and transfusion requirements. We evaluated a new technique to assess the effect of perioperative aspirin ingestion on platelet function in cardiac surgical patients.

Corinna Velik-Salchner, Stephan Maier, Petra Innerhofer, Werner Streif, Anton Klingler, Christian Kolbitsch, and Dietmar Fries

Point-of-Care Whole Blood Impedance Aggregometry Versus Classical Light Transmission Aggregometry for Detecting Aspirin and Clopidogrel: The Results of a Pilot Study
Anesth Analg 2008 107: 1798-1806. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The bedside Multiplate technique seems to be useful for the preoperative detection of the effects of aspirin alone or aspirin combined with clopidogrel. Our results are as reliable as those obtained with classical light transmission aggregometry, considered to be the "gold standard" for platelet function testing.

Nina C. Weber, Jan Fräβdorf, Christoph Ratajczak, Yvonne Grueber, Wolfgang Schlack, Markus W. Hollmann, and Benedikt Preckel

Xenon Induces Late Cardiac Preconditioning In Vivo: A Role for Cyclooxygenase 2?
Anesth Analg 2008 107: 1807-1813. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The noble gas xenon induces cardiac late preconditioning resembling ischemic late preconditioning. However, both preconditioning forms show distinct intracellular pathways.

Sang-Hyun Park, Sung-Hee Han, Sang-Hwan Do, Jung-Won Kim, Ka-young Rhee, and Jin-Hee Kim

Prophylactic Dexamethasone Decreases the Incidence of Sore Throat and Hoarseness After Tracheal Extubation with a Double-Lumen Endobronchial Tube
Anesth Analg 2008 107: 1814-1818. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Our results suggest that the prophylactic administration of IV dexamethasone, 0.2 mg/kg, effectively reduces the incidence and severity of postoperative sore throat and hoarseness in patients after tracheal extubation with a double-lumen endobronchial tube.

K. Annette Mizuguchi, Amanda A. Fox, Thomas M. Burch, Lawrence H. Cohn, and John A. Fox

Tricuspid and Mitral Valve Carcinoid Disease in the Setting of a Patent Foramen Ovale (Echo Rounds)
Anesth Analg 2008 107: 1819-1821. [Full Text] [PDF] [CME] [Echo Loops]  [Request Permissions]  

Bettina Jungwirth, David B. Adams, Joseph P. Mathew, Madhav Swaminathan, Donald D. Glower, and G. Burkhard Mackensen

Mitral Valve Prolapse and Systolic Anterior Motion Illustrated by Real Time Three-Dimensional Transesophageal Echocardiography (Echo Rounds)
Anesth Analg 2008 107: 1822-1824. [Full Text] [PDF] [CME] [Echo Loops]  [Request Permissions]  

Denise Joffe, Michelle Gurvitz, and Donald Oxorn

An Unusual Presentation in a Patient with Shone’s Anomaly (Echo Rounds)
Anesth Analg 2008 107: 1825-1827. [Full Text] [PDF] [Echo Loops]  [Request Permissions]  

William J. Mauermann, Kent H. Rehfeldt, James J. Lynch, Roger L. Click, and Joseph A. Dearani

Functional Right-to-Left Shunt Caused by Deliberate Closure of the Coronary Sinus Orifice (Echo Rounds)
Anesth Analg 2008 107: 1828-1829. [Full Text] [PDF] [CME] [Echo Loops]  [Request Permissions]  

PEDIATRIC ANESTHESIOLOGY:

Christopher Heard, Frederick Burrows, Kristin Johnson, Prashant Joshi, James Houck, and Jerrold Lerman

A Comparison of Dexmedetomidine-Midazolam with Propofol for Maintenance of Anesthesia in Children Undergoing Magnetic Resonance Imaging
Anesth Analg 2008 107: 1832-1839. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Dexmedetomidine provides adequate anesthesia for magnetic resonance imaging after a sevoflurane induction, although early recovery is prolonged compared with propofol. The hemodynamic responses after dexmedetomidine administration differed from those after propofol.

Laura A. Hastings, John C. Wood, Bryan Harris, Sabine Von Busse, Ana Drachenberg, Frederick Dorey, and Gerald A. Bushman

Cardiac Medications Are Not Associated with Clinically Important Preoperative Electrolyte Disturbances in Children Presenting for Cardiac Surgery
Anesth Analg 2008 107: 1840-1847. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This investigation examines the incidence of abnormal laboratory values in children taking cardiac medications. Although there were some significant differences in preoperative electrolyte values between patients taking different numbers of medications, they were not of clinical importance. Hypokalemia and hypomagnesemia were not identified in this study population. These data do not support the need for routine preoperative electrolyte evaluation in children and young adults taking cardiac medications.

Thomas M. Burch, Francis X. McGowan, Jr, Barry D. Kussman, Andrew J. Powell, and James A. DiNardo

Congenital Supravalvular Aortic Stenosis and Sudden Death Associated with Anesthesia: What’s the Mystery? (Special Article)
Anesth Analg 2008 107: 1848-1854. [Abstract] [Full Text] [PDF] [Video Clips]  [Request Permissions]  

IMPLICATIONS: Patients with congenital supravalvular aortic stenosis and associated peripheral pulmonary artery stenoses are inherently at risk for development of myocardial ischemia particularly in the setting of procedural sedation and anesthesia. All patients with congenital supravalvular aortic stenosis should be considered at risk for myocardial ischemia on multiple bases and treated accordingly.

AMBULATORY ANESTHESIOLOGY:

Kai Goldmann, Carolin Hechtfischer, Amena Malik, Andrea Kussin, and Christian Freisburger

Use of ProSeal^TM Laryngeal Mask Airway in 2114 Adult Patients: A Prospective Study
Anesth Analg 2008 107: 1856-1861. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Use of the ProSealTM laryngeal mask airway is safe and effective in a general practice setting. A correctly positioned ProSealTM laryngeal mask airway can protect from pulmonary aspiration of regurgitate gastric fluid and seems to be a valuable device for the management of the difficult airway.

ANESTHETIC PHARMACOLOGY:

Hendrikus J. M. Lemmens, Lawrence J. Saidman, Edmond I. Eger, II, and Michael J. Laster

Obesity Modestly Affects Inhaled Anesthetic Kinetics in Humans
Anesth Analg 2008 107: 1864-1870. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Obesity in humans can increase the concentrations of inhaled and delivered anesthetic needed to sustain a constant alveolar concentration, particularly after several hours of anesthesia, and particularly with a more soluble (isoflurane) than with a less soluble (desflurane) anesthetic, but the increase relative to body mass is small.

Norimasa Ohtani, Kotaro Kida, Kazuhiro Shoji, Yutaka Yasui, and Eiji Masaki

Recovery Profiles from Dexmedetomidine as a General Anesthetic Adjuvant in Patients Undergoing Lower Abdominal Surgery
Anesth Analg 2008 107: 1871-1874. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: When dexmedetomidine is combined with propofol, time to open eyes is longer than propofol or sevoflurane alone or dexmedetomidine combined with sevoflurane.

Jörg Ahrens, Martin Leuwer, Sina Stachura, Klaus Krampfl, Delia Belelli, Jeremy J. Lambert, and Gertrud Haeseler

A Transmembrane Residue Influences the Interaction of Propofol with the Strychnine-Sensitive Glycine ₁ and ₁β Receptor
Anesth Analg 2008 107: 1875-1883. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Exchange of a single amino acid residue at the {alpha}1 glycine receptor subunit decreases the sensitivity of the receptor to propofol. These results provide the prerequisites for creation of glycine receptor knockin mice clarifying the contribution of glycine receptors to the antinociceptive actions of propofol.

Ke-Xuan Liu, Shu-Qing Chen, Wen-Qi Huang, Yun-Sheng Li, Michael G. Irwin, and Zhengyuan Xia

Propofol Pretreatment Reduces Ceramide Production and Attenuates Intestinal Mucosal Apoptosis Induced by Intestinal Ischemia/Reperfusion in Rats
Anesth Analg 2008 107: 1884-1891. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Pretreatment with propofol at a sedative dose attenuates intestinal ischemia-reperfusion induced intestinal mucosa injury. This property may be beneficial when propofol is used in clinical circumstances related to intestinal ischemia-reperfusion such as abdominal aortic aneurysm surgery, small bowel surgery, transplantation and cardiopulmonary bypass.

Kazumi Niinomi, Yoshiko Banno, Hiroki Iida, and Shuji Dohi

Nicorandil, an Adenosine Triphosphate-Sensitive Potassium Channel Opener, Inhibits Muscarinic Acetylcholine Receptor-Mediated Activation of Extracellular Signal-Regulated Kinases in PC12 Cells
Anesth Analg 2008 107: 1892-1898. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: An adenosine triphosphate-sensitive potassium channel opener nicorandil inhibits muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase, which is implicated in the suppression of the increase of intracellular Ca2+ concentration in PC12 cells.

Walid Habre, Ágnes Adamicza, Enikõ Lele, Tímea Novák, Peter D. Sly, and Ferenc Petak

The Involvement of Histaminic and Muscarinic Receptors in the Bronchoconstriction Induced by Myorelaxant Administration in Sensitized Rabbits
Anesth Analg 2008 107: 1899-1906. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Muscle relaxants mainly induce constriction of allergic airways via histamine release, but their interactions with muscarinic receptors also contribute to alterations of the airway tone.

TECHNOLOGY, COMPUTING, AND SIMULATION:

Dale F. Szpisjak, Elizabeth N. Javernick, Richard R. Kyle, and Paul N. Austin

Oxygen Consumption of a Pneumatically Controlled Ventilator in a Field Anesthesia Machine
Anesth Analg 2008 107: 1907-1911. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The oxygen consumption of a field anesthesia machine depends upon gas flows, ventilator settings, and thoracic compliance. Estimates of supply duration for E- and H-cylinders are provided but actual results will vary from patient to patient. When using a field anesthesia machine with cylinder oxygen supply, the pressure manometer mounted on the cylinder should be monitored as a guide to remaining gas supply.

PATIENT SAFETY:

Srikantha L. Rao, Allen R. Kunselman, H. Gregg Schuler, and Susan DesHarnais

Laryngoscopy and Tracheal Intubation in the Head-Elevated Position in Obese Patients: A Randomized, Controlled, Equivalence Trial
Anesth Analg 2008 107: 1912-1918. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: In obese patients, the 25-degree back-up position before induction is a key step in achieving good intubating conditions after direct laryngoscopy. This head-elevated laryngoscopic position, usually achieved by placing patients on a ramp created using blankets, can also be achieved by reconfiguring the operating room table to create a table ramp. This table-ramp method can be used under urgent conditions, without the added expense of positioning devices, and may prevent possible injury to the patient or providers that can occur during removal of positioning devices after intubation.

George A. Mashour, Sachin Kheterpal, Vishnu Vanaharam, Amy Shanks, Luke Y.-J. Wang, Warren S. Sandberg, and Kevin K. Tremper

The Extended Mallampati Score and a Diagnosis of Diabetes Mellitus Are Predictors of Difficult Laryngoscopy in the Morbidly Obese
Anesth Analg 2008 107: 1919-1923. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study demonstrates that performing the modified Mallampati examination with the patient in craniocervical extension (Extended Mallampati Score) improves the predictive value in the morbidly obese. Furthermore, it identifies diabetes mellitus as a predictor of difficult laryngoscopy in this population. Finally, the study supports the finding that morbid obesity is not itself a risk factor for difficult laryngoscopy.

Michael J. Bishop, Jennifer E. Souders, Cecilia M. Peterson, William G. Henderson, and Karen B. Domino

Factors Associated with Unanticipated Day of Surgery Deaths in Department of Veterans Affairs Hospitals
Anesth Analg 2008 107: 1924-1935. [Abstract] [Full Text] [PDF] [CME] [Request Permissions]  

IMPLICATIONS: Unanticipated death on the day of surgery occurs rarely, and is best predicted by the underlying disease of the patient. Opportunities for improvement in anesthesia care identified included better monitoring during the transfer to recovery or intensive care and prevention of myocardial infarction.

Joel B. Gunter, John Ball, and Sean Than-Win

Preparation of the Dräger Fabius Anesthesia Machine for the Malignant–Hyperthermia Susceptible Patient
Anesth Analg 2008 107: 1936-1945. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Eliminating trace concentrations of sevoflurane from the Drager Fabius anesthesia machine using standard flushing methods requires more time than in older, conventional anesthesia machines. Activated charcoal filters can effectively scrub sevoflurane from inspired gases, avoiding the need for prolonged flushing before using the Drager Fabius in patients susceptible to malignant hyperthermia.

Masahiko Tsuchiya, Eisuke F. Sato, Masayasu Inoue, and Akira Asada

Open Abdominal Surgery Increases Intraoperative Oxidative Stress: Can It Be Prevented?
Anesth Analg 2008 107: 1946-1952. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: An open abdominal procedure increases oxidative stress in surgical patients, whereas a laparoscopic procedure or propofol anesthesia reduces this risk.

Thierry Girard, Markus Suhner, Soledad Levano, Martine Singer, Andreas Zollinger, and Christoph K. Hofer

A Fulminant Malignant Hyperthermia Episode in a Patient with Ryanodine Receptor Gene Mutation p.Tyr522Ser (Case Report)
Anesth Analg 2008 107: 1953-1955. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This report describes a case of fulminant malignant hyperthermia and its clinical management. In convincing episodes of malignant hyperthermia, molecular genetic testing is appropriate as the first in-vitro laboratory diagnostic test.

CRITICAL CARE AND TRAUMA:

José G. M. Hofhuis, Peter E. Spronk, Henk F. van Stel, Augustinus J. P. Schrijvers, Johannes H. Rommes, and Jan Bakker

The Impact of Severe Sepsis on Health-Related Quality of Life: A Long-Term Follow-Up Study
Anesth Analg 2008 107: 1957-1964. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study indicates that health-related quality of life in severe sepsis survivors recovers slowly to values approaching baseline after a sharp multidimensional decrease during intensive care unit (ICU) stay. This poor health-related quality of life during ICU stay implies that ICU rehabilitation programs should start early.

Michael Woo, Michael O'Connor, Chun-Su Yuan, and Jonathan Moss

Reversal of Opioid-Induced Gastric Dysfunction in a Critically Ill Burn Patient After Methylnaltrexone (Case Report)
Anesth Analg 2008 107: 1965-1967. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We report the use of IV methylnaltrexone to facilitate feeding in a critically ill burn patient. After injection of the peripheral opiate antagonist, the patient's gastric residuals markedly decreased and the enteral feeding markedly increased.

OBSTETRIC ANESTHESIOLOGY:

Yvonne Lim, Cecilia E. Ocampo, Mia Supandji, Wendy H. L. Teoh, and Alex T. Sia

A Randomized Controlled Trial of Three Patient-Controlled Epidural Analgesia Regimens for Labor
Anesth Analg 2008 107: 1968-1972. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Demand-only patient-controlled labor analgesia was associated with a greater incidence of breakthrough pain, higher intrapartum pain scores, and decreased duration of effective analgesia and maternal satisfaction compared with patient-controlled analgesia with a background infusion and shorter lockout interval. However, local anesthetic consumption was higher and the duration of the second stage of labor was longer.

Katherine W. Arendt, Heidi M. Connolly, Carole A. Warnes, William J. Watson, James R. Hebl, and Paula A. Craigo

Anesthetic Management of Parturients with Congenitally Corrected Transposition of the Great Arteries: Three Cases and a Review of the Literature (Case Report)
Anesth Analg 2008 107: 1973-1977. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Obstetric anesthesia management of parturients with congenitally corrected transposition of the great arteries involves careful consideration of systemic ventricular function, heart rhythm, and associated cardiac lesions.

Marnie B. Robinson, Timothy M. Crombleholme, and Charles D. Kurth

Maternal Pulmonary Edema During Fetoscopic Surgery (Case Report)
Anesth Analg 2008 107: 1978-1980. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: We report pulmonary edema in a healthy mother undergoing minimally invasive fetal surgery in order to alert the reader to the potential etiology and prevention of this complication.

ECONOMICS, EDUCATION, AND POLICY:

David L. Reich, Maria Galati, Marina Krol, Carol A. Bodian, and Ronald A. Kahn

A Mission-Based Productivity Compensation Model for an Academic Anesthesiology Department
Anesth Analg 2008 107: 1981-1988. [Abstract] [Full Text] [PDF] [Data Supplement]  [Request Permissions]  

IMPLICATIONS: Increased clinical productivity and salaries were achieved with fewer clinical faculty and stable educational and academic output with the introduction of a mission-based productivity compensation model.

Danielle Masursky, Franklin Dexter, and Nancy A. Nussmeier

Operating Room Nursing Directors’ Influence on Anesthesia Group Operating Room Productivity
Anesth Analg 2008 107: 1989-1996. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Among 303 operating room (OR) nursing directors responding to a survey conducted by the OR Manager publication from the United States, the size of the budget was the principal predictor of salary. Among 164 nomination letters for "OR Manager of the Year," only a small proportion (<3%) of sentences included a profit, productivity, or finance term. Anesthesia groups should champion initiatives to increase anesthesia productivity, while being sensitive to institutional expectations of nursing directors.

NEUROSURGICAL ANESTHESIOLOGY AND NEUROSCIENCE:

Massimo Giannessi, Mauro Ursino, and W. Bosseau Murray

The Design of a Digital Cerebrovascular Simulation Model for Teaching and Research
Anesth Analg 2008 107: 1997-2008. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The generic model can be used by clinicians to teach and investigate the complex study of multiple simultaneous interactions of intracranial pressure and cerebral blood flow, as well as to individualize the model's parameters to mimic a specific patient to optimize therapeutic modalities.

Yue-Ying Zheng, Yun-Ping Lan, Hui-Fang Tang, and Sheng-Mei Zhu

Propofol Pretreatment Attenuates Aquaporin-4 Over-Expression and Alleviates Cerebral Edema After Transient Focal Brain Ischemia Reperfusion in Rats
Anesth Analg 2008 107: 2009-2016. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This study demonstrates that, in rats, propofol pretreatment reduces cerebral edema induced by transient focal cerebral ischemia with reperfusion. This is associated with a reduction in the over-expression of AQP4.

ANALGESIA:

Kyle S. Christensen, Amy E. Cohen, Fred H. Mermelstein, Douglas A. Hamilton, Ewan McNicol, Najib Babul, and Daniel B. Carr

The Analgesic Efficacy and Safety of a Novel Intranasal Morphine Formulation (Morphine plus Chitosan), Immediate Release Oral Morphine, Intravenous Morphine, and Placebo in a Postsurgical Dental Pain Model
Anesth Analg 2008 107: 2018-2024. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Intranasal morphine 15 mg demonstrated analgesic efficacy and safety similar to IV morphine 7.5 mg in moderate-to-severe postsurgical pain after third molar extraction.

John E. Moodie, Colin R. Brown, Eileen J. Bisley, Hans U. Weber, and Lincoln Bynum

The Safety and Analgesic Efficacy of Intranasal Ketorolac in Patients with Postoperative Pain
Anesth Analg 2008 107: 2025-2031. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This clinical study shows that 30 mg of intranasal ketorolac provides significant analgesia after major surgery.

Yu Xuerong, Huang Yuguang, Ju Xia, and Wang Hailan

Ketamine and Lornoxicam for Preventing a Fentanyl-Induced Increase in Postoperative Morphine Requirement
Anesth Analg 2008 107: 2032-2037. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This randomized, double-blind, placebo-controlled study showed that intraoperative administration of fentanyl could increase postoperative morphine consumption. Administering ketamine or lornoxicam in combination with fentanyl could help avoid this increased consumption.

Yanxia Sun and Tong J. Gan

Acupuncture for the Management of Chronic Headache: A Systematic Review
Anesth Analg 2008 107: 2038-2047. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: This systematic review demonstrated that traditional needling acupuncture is superior to sham acupuncture and pharmacological therapy for chronic headache treatment by improving headache intensity and frequency and increasing the response rate.

Regina Kleinert, Claudia Lange, Achim Steup, Peter Black, Jutta Goldberg, and Paul Desjardins

Single Dose Analgesic Efficacy of Tapentadol in Postsurgical Dental Pain: The Results of a Randomized, Double-Blind, Placebo-Controlled Study
Anesth Analg 2008 107: 2048-2055. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Tapentadol is a highly effective, centrally acting analgesic with a favorable side effect profile and rapid onset of action.

John Carney, John G. McDonnell, Alan Ochana, Raj Bhinder, and John G. Laffey

The Transversus Abdominis Plane Block Provides Effective Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy
Anesth Analg 2008 107: 2056-2060. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: The transversus abdominis plane block, when used as part of a multimodal analgesic regimen, provided enhanced pain relief and reduced the need for supplemental opioids after total abdominal hysterectomy.

Ignacio Lizarraga, J. Paul Chambers, and Craig B. Johnson

Prevention of N-Methyl-d-Aspartate-Induced Mechanical Nociception by Intrathecal Administration of Ketoprofen and Ketamine in Sheep
Anesth Analg 2008 107: 2061-2067. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Intrathecal administration of N-methyl-d-aspartate induced mechanical nociception in sheep, which was prevented by ketoprofen and ketamine, given alone or in combination through the same route. Drug combinations are widely used clinically, and that of ketoprofen and ketamine may have therapeutic potential in conditions associated with persistent pain.

Meltem Cakmak Hafizoglu, Kaan Katircioglu, Murat Y. Ozkalkanli, and Serdar Savaci

Bupivacaine Infusion Above or Below the Fascia for Postoperative Pain Treatment After Abdominal Hysterectomy
Anesth Analg 2008 107: 2068-2072. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Local anesthetic infusion above the fascia provides better postoperative analgesia compared with infusion below the fascia for the first 12 postoperative hours in patients undergoing abdominal hysterectomy.

Ed T. Kamphuis, Peter W. Kuipers, Ger E. van Venrooij, and Cor J. Kalkman

The Effects of Spinal Anesthesia with Lidocaine and Sufentanil on Lower Urinary Tract Functions
Anesth Analg 2008 107: 2073-2078. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: After using a combination of lidocaine 100 mg and sufentanil 20 {micro}g for spinal anesthesia, return of the urge to void is not synonymous with return of the ability to void.

Francis Remerand, Anne Sophie Vuitton, Michel Palud, Sylvie Buchet, Xavier Pourrat, Annick Baud, Marc Laffon, and Jacques Fusciardi

Elastomeric Pump Reliability in Postoperative Regional Anesthesia: A Survey of 430 Consecutive Devices
Anesth Analg 2008 107: 2079-2084. [Abstract] [Full Text] [PDF] [Request Permissions]  

IMPLICATIONS: Local anesthetic flow rate delivered by elastomeric pumps for regional postoperative analgesia is less reliable than reported by manufacturers and in vitro studies.

Manuel Taboada Muñiz, Jaime Rodríguez, María Bermúdez, Cristina Valiño, Noemi Blanco, Marcos Amor, Pilar Aguirre, Ana Masid, Joaquin Cortes, Julián Álvarez, and Peter G. Atanassoff

Low Volume and High Concentration of Local Anesthetic Is More Efficacious than High Volume and Low Concentration in Labat's Sciatic Nerve Block: A Prospective, Randomized Comparison
Anesth Analg 2008 107: 2085-2088. [Abstract] [Full Text] [PDF] [Request Permissions]  

COCHRANE CORNER:

K. Leslie, O. Clavisi, and J. Hargrove

Target-Controlled Infusion Versus Manually-Controlled Infusion of Propofol for General Anaesthesia or Sedation in Adults
Anesth Analg 2008 107: 2089. [Full Text] [PDF] [Request Permissions]  

M. B. Alhassan, F. Kyari, and H. OD Ejere

Peribulbar Versus Retrobulbar Anaesthesia for Cataract Surgery
Anesth Analg 2008 107: 2089. [Full Text] [PDF] [Request Permissions]  

LETTERS TO THE EDITOR:

Michael J. Bishop, William G. Henderson, and Karen B. Domino

Regression Analysis for a Large Database
Anesth Analg 2008 107: 2090. [Full Text] [PDF] [Request Permissions]  

Maria Armstrong

Clarification Required Regarding Results of Morphine PCA/Ketamine Trial
Anesth Analg 2008 107: 2090-2091. [Full Text] [PDF] [Request Permissions]  

Pr Hervé Dupont

Clarification Required Regarding Results of Morphine PCA/Ketamine Trial
Anesth Analg 2008 107: 2091. [Full Text] [PDF] [Request Permissions]  

Dominique M. Vandijck, Stijn I. Blot, Linos Vandekerckhove, and Dirk P. Vogelaers

Fluconazole Exposure and Selection for Candida Non-albicans
Anesth Analg 2008 107: 2091. [Full Text] [PDF] [Request Permissions]  

George Dimopoulos and Matthew E. Falagas

Selection for Candida Non-albicans spp. After Fluconazole Use
Anesth Analg 2008 107: 2091-2092. [Full Text] [PDF] [Request Permissions]  

Jyotsna Punj, V. Darlong, R. Pandey, and Chandralekha

Thirty-five Franklin Size Double Lumen Tube May Not Be Suitable for Tall Patients
Anesth Analg 2008 107: 2092. [Full Text] [PDF] [Request Permissions]  

David Amar, Dawn P. Desiderio, and Paul M. Heerdt

Thirty-five Franklin Size Double Lumen Tube May Not Be Suitable for Tall Patients
Anesth Analg 2008 107: 2092. [Full Text] [PDF] [Request Permissions]  

Zafer Tabboush

Intraarticular Tramadol or "Hot Chili Peppers"?
Anesth Analg 2008 107: 2092-2093. [Full Text] [PDF] [Request Permissions]  

Ahed Zeidan and Michel M. R. F. Struys

Intraarticular Tramadol or "Hot Chili Peppers"?
Anesth Analg 2008 107: 2093. [Full Text] [PDF] [Request Permissions]  

Guido Schüpfer and Mattias Casutt

Coagulation Monitoring
Anesth Analg 2008 107: 2093. [Full Text] [PDF] [Request Permissions]  

Christoph K. Hofer and Michael T. Ganter

Coagulation Monitoring
Anesth Analg 2008 107: 2093-2094. [Full Text] [PDF] [Request Permissions]  

Ki Jinn Chin, Anahi Perlas, Richard Brull, and Vincent W. S. Chan

Ultrasound Guidance is Advantageous in Popliteal Nerve Blockade
Anesth Analg 2008 107: 2094. [Full Text] [PDF] [Request Permissions]  

Eric Dufour and Marc Fischler

Ultrasound Guidance is Advantageous in Popliteal Nerve Blockade
Anesth Analg 2008 107: 2094-2095. [Full Text] [PDF] [Request Permissions]  

Rajeev Sharma, Rakesh Kumar, Sunil Kumar, and Neera R. Gupta

Connector Assembly to Improve Performance of the Lighted Stylet (Trachlight^TM) for Nasotracheal Intubation
Anesth Analg 2008 107: 2095-2096. [Full Text] [PDF] [Request Permissions]  

Stacie Deiner and Irene P. Osborn

Supremely Secured
Anesth Analg 2008 107: 2096. [Full Text] [PDF] [Request Permissions]  

Katherine Arendt, Jie Zhou, Scott Segal, and William Camann

Childbirth Time Selection Based on Religious Belief
Anesth Analg 2008 107: 2096-2097. [Full Text] [PDF] [Request Permissions]  

BOOK AND MULTIMEDIA REVIEWS:

Rahul Koka and James H. Philip

Understanding Anesthesia Equipment, 5th ed.
Anesth Analg 2008 107: 2098. [Full Text] [PDF] [Request Permissions]  

Feroze Mahmood and Albert T. Cheung

Interactive TEE Review: Self-Assessment Examination (DVD-ROM)
Anesth Analg 2008 107: 2098-2100. [Full Text] [PDF] [Request Permissions]  

ERRATA:

ERRATUM
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ERRATUM
Anesth Analg 2008 107: 2078. [Full Text] [PDF] [Request Permissions]  

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