EDITORIALS:

Robert F. Bedford and Harlan E. Ives

The Renal Safety of Sevoflurane
Anesth Analg 2000 90: 505-508. [Full Text]  

CARDIOVASCULAR ANESTHESIA:

E. Price Stover, Lawrence C. Siegel, Patricia A. Hood, Geraldine E. O’Riordan, and Timothy R. McKenna

Platelet-Rich Plasma Sequestration, with Therapeutic Platelet Yields, Reduces Allogeneic Transfusion in Complex Cardiac Surgery
Anesth Analg 2000 90: 509-516. [Abstract] [Full Text]  

Implications: Transfusion of allogeneic blood products, including platelets, is common during complex cardiac surgical procedures. In the present prospective, randomized study, a significant reduction in allogeneic platelet transfusion and total allogeneic units transfused was observed after the reinfusion of a therapeutic quantity of autologous platelets sequestered before cardiopulmonary bypass.

Olivier Y. Cuignet, Brent L. Wood, Wayne L. Chandler, and Bruce D. Spiess

A Second-Generation Blood Substitute (Perfluorodichlorooctane Emulsion) Generates Spurious Elevations in Platelet Counts from Automated Hematology Analyzers
Anesth Analg 2000 90: 517-522. [Abstract] [Full Text]  

Implications: Perfluorocarbons are being investigated under conditions in which thrombocytopenia is likely to occur. In this in vitro study, we demonstrate significant overestimates in platelet counts from automated cell counters at clinically relevant perfluorocarbon concentrations in thrombocytopenic blood samples.

Angela Rajek, Thomas Pernerstorfer, Johannes Kastner, Peter Mares, Martin Grabenwöger, Daniel I. Sessler, Georg Grubhofer, and Michael Hiesmayr

Inhaled Nitric Oxide Reduces Pulmonary Vascular Resistance More Than Prostaglandin E₁ During Heart Transplantation
Anesth Analg 2000 90: 523-530. [Abstract] [Full Text]  

Implications: Nitric oxide inhalation selectively reduces pulmonary vascular resistance and pulmonary artery pressure immediately after heart transplantation which facilitates weaning from cardiopulmonary bypass.

Wei Lu, TGK Mant, Jerrold H. Levy, and James M. Bailey

Pharmacokinetics of Recombinant Transgenic Antithrombin in Volunteers
Anesth Analg 2000 90: 531-534. [Abstract] [Full Text]  

Implications: A single supplemental dose of transgenic recombinant antithrombin restoring levels to 120%-150% of normal can provide adequate levels for the usual duration of cardiopulmonary bypass.

Javier H. Campos, F. Christopher Massa, and Kemp H. Kernstine

The Incidence of Right Upper-Lobe Collapse When Comparing a Right-Sided Double-Lumen Tube Versus a Modified Left Double-Lumen Tube for Left-Sided Thoracic Surgery
Anesth Analg 2000 90: 535-540. [Abstract] [Full Text]  

Implications: In this study, right-sided double-lumen tubes (R-DLTs) were compared with modified left-sided double-lumen tubes in patients requiring one-lung ventilation for left-sided thoracic surgery. The incidence of right upper-lobe collapse was assessed intraoperatively by a chest radiograph which showed no collapse of the right upper lobe in all patients who received R-DLTs or left-sided double-lumen tubes. Therefore, we conclude that R-DLTs present no increased risk of complications for left-sided thoracic surgery and should not be abandoned.

Vance G. Nielsen and Manuel S. Baird

Extreme Hemodilution in Rabbits: An In Vitro and In Vivo Thrombelastographic® Analysis
Anesth Analg 2000 90: 541-545. [Abstract] [Full Text]  

Implications: The effects of hemodilution and the fluid used on Thrombelastographic(R) (Haemoscope, Skokie, IL) variables are markedly different between in vitro and in vivo hemodilution studies.

Emmanuel Samain, Hélène Bouillier, Jean Marty, Michel Safar, and Georges Dagher

The Effect of Propofol on Angiotensin II-Induced Ca²⁺ Mobilization in Aortic Smooth Muscle Cells from Normotensive and Hypertensive Rats
Anesth Analg 2000 90: 546-552. [Abstract] [Full Text]  

Implications: In rat aortic vascular smooth muscle cells, propofol reduced angiotensin II-elicited Ca2+ entry through capacitative Ca2+ channels without altering Ca2+ release from intracellular stores. Spontaneously hypertensive rats were more sensitive to these effects of propofol than normotensive rats. The response of vascular smooth muscle cells to angiotensin II may be altered by propofol.

Kevin R. Dasen, David G. Niswander, and Richard E. Schlenker

Autologous and Allogenic Blood Products for Unanticipated Massive Blood Loss in a Jehovah’s Witness (Case Report)
Anesth Analg 2000 90: 553-555. [Full Text]  

M. T. Sanjoaquín, J. R. Fraile, A. Gutiérrez, M. I. Canal, and J. Navia

Hypertensive Crisis During a Transurethral Resection of the Bladder: Nondiagnosed Bladder Paraganglioma (Case Report)
Anesth Analg 2000 90: 556-558. [Full Text] En Espanol  

Randall M. Schell and Daniel J. Cole

Cerebral Monitoring: Jugular Venous Oximetry (Medical Intelligence)
Anesth Analg 2000 90: 559-566. [Full Text]  

AMBULATORY ANESTHESIA:

Zsuzsanna Gesztesi, Monica M. Sa Rego, and Paul F. White

The Comparative Effectiveness of Fentanyl and its Newer Analogs During Extracorporeal Shock Wave Lithotripsy Under Monitored Anesthesia Care (Brief Report)
Anesth Analg 2000 90: 567-570. [Full Text]  

PEDIATRIC ANESTHESIA:

Shu-Ming Wang and Zeev N. Kain

Preoperative Anxiety and Postoperative Nausea and Vomiting in Children: Is There an Association?
Anesth Analg 2000 90: 571-575. [Abstract] [Full Text]  

Implications: This study was performed to explore a possible association between children's anxiety before surgery and postoperative nausea and vomiting. We found that controlling for confounding variables, anxiety in the preoperative holding area has no predictive value for the occurrence of postoperative nausea and vomiting.

John B. Rose, Mary C. Theroux, and Michael S. Katz

The Potency of Succinylcholine in Obese Adolescents
Anesth Analg 2000 90: 576-578. [Abstract] [Full Text]  

Implications: The potency estimates for succinylcholine in obese (body mass index > 30 kg/m2) adolescents are comparable to those in similarly aged nonobese adolescents when dosing is calculated based on total body mass and not lean body mass. When a rapid sequence induction of anesthesia is considered in an obese adolescent, the dose of succinylcholine should be based on actual (not lean) body mass.

Sibylle A. Kozek-Langenecker, Peter Marhofer, Karin Jonas, Tom Macik, Georg Urak, and Margot Semsroth

Cardiovascular Criteria for Epidural Test Dosing in Sevoflurane- and Halothane-Anesthetized Children
Anesth Analg 2000 90: 579-583. [Abstract] [Full Text]  

Implications: We found a greater reliability of the T wave criterion over conventional hemodynamic criteria for detecting intravascular injection of a simulated epidural test dose. Sevoflurane may increase the likelihood of recognition of an accidental intravascular injection of epinephrine-containing solutions in clinical practice compared with halothane.

ECONOMICS AND HEALTH SYSTEMS RESEARCH:

Laurent G. Glance

The Cost Effectiveness of Anesthesia Workforce Models: A Simulation Approach Using Decision-Analysis Modeling
Anesth Analg 2000 90: 584-592. [Abstract] [Full Text]  

Implications: An anesthesia care-team approach with a physician to certified registered nurse anesthetist (CRNA) ratio of 1:2 is the preferred staffing scenario for intermediate-risk patients. Although medical direction of CRNAs caring for low-risk patients is cost-effective, the small improvement in outcome resulting from increasing the physician to CRNA ratio from 1:8 to 1:4 may not be justified by the added cost.

ECONOMICS AND HEALTH SYSTEMS MANAGEMENT:

Srinivas Mantha, Michael F. Roizen, Lee A. Fleisher, Ronald Thisted, and Joseph Foss

Comparing Methods of Clinical Measurement: Reporting Standards for Bland and Altman Analysis
Anesth Analg 2000 90: 593-602. [Abstract] [Full Text]  

Implications: A literature review of anesthesia journals revealed several inadequacies and inconsistencies in statistical reports of results of comparison studies with regard to interchangeability of measurement methods. We encourage journal editors to evaluate submissions on this subject carefully to ensure that their readers can draw valid conclusions about the value of new technologies.

NEUROSURGICAL ANESTHESIA:

Oak Za Chi, Doo Ik Lee, Xia Liu, and Harvey R. Weiss

The Effects of Morphine on Blood-Brain Barrier Disruption Caused by Intracarotid Injection of Hyperosmolar Mannitol in Rats
Anesth Analg 2000 90: 603-608. [Abstract] [Full Text]  

Implications: Our study suggests that morphine may be effective in reducing the blood-brain barrier disruption by hyperosmolar mannitol without significant effects on systemic blood pressure.

Ingo H. Lorenz, Christian Kolbitsch, Christoph Hörmann, Michael Schocke, Fritz Zschiegner, Stephan Felber, and Arnulf Benzer

The Effects of Remifentanil on Cerebral Capacity in Awake Volunteers
Anesth Analg 2000 90: 609-613. [Abstract] [Full Text] En Espanol  

Implications: Knowledge about the influence of remifentanil on cerebral capacity is crucial before routine use of the drug in neuroanesthesia. Thus, we assessed the influence of remifentanil on cerebral capacity noninvasively by means of phase-contrast magnetic resonance imaging measurement of systolic cerebrospinal fluid peak velocity in the aqueduct of Sylvius in humans.

CRITICAL CARE AND TRAUMA:

Jonathan G. Hardman, Jonathan S. Wills, and Alan R. Aitkenhead

Investigating Hypoxemia during Apnea: Validation of a Set of Physiological Models
Anesth Analg 2000 90: 614-618. [Abstract] [Full Text]  

Implications: We used mathematical, physiological models to recreate the methods and subjects of four clinical studies investigating oxygenation and low oxygen levels during cessation of breathing. Our aim was to validate the models, allowing theoretical investigations into this area. The blindly recreated results closely matched the clinical studies, validating the models.

Jonathan G. Hardman, Jonathan S. Wills, and Alan R. Aitkenhead

Factors Determining the Onset and Course of Hypoxemia During Apnea: An Investigation Using Physiological Modelling
Anesth Analg 2000 90: 619-624. [Abstract] [Full Text]  

Implications: Reduction in oxygen levels during cessation of breathing is dangerous and common in anesthetic practice. We used validated, mathematical, physiological models to reveal the impact of physiological factors on the deterioration of oxygen levels. This study could not be performed on patients and reveals important information.

Lars G. Fischer, Markus W. Hollmann, Damian J. Horstman, and George F. Rich

Cyclooxygenase Inhibitors Attenuate Bradykinin-Induced Vasoconstriction in Septic Isolated Rat Lungs
Anesth Analg 2000 90: 625-631. [Abstract] [Full Text]  

Implications: This study demonstrated that, in an isolated rat lung model, nonselective inhibition of the cyclooxygenase pathway, and possibly selective inhibition of the inducible cyclooxygenase-2 isoform, may attenuate sepsis-induced endothelial dysfunction.

OBSTETRIC ANESTHESIA:

Greg C. Meister, Robert D’Angelo, Medge Owen, Kenneth E. Nelson, and Renee Gaver

A Comparison of Epidural Analgesia with 0.125% Ropivacaine with Fentanyl Versus 0.125% Bupivacaine with Fentanyl during Labor
Anesth Analg 2000 90: 632-637. [Abstract] [Full Text] En Espanol  

Implications: By using a patient-controlled epidural analgesia technique, ropivacaine 0.125% with fentanyl 2 {micro}g/mL produces similar analgesia with significantly less motor block than a similar concentration of bupivacaine with fentanyl during labor. Whether this statistical reduction in motor block improves clinical outcome or is applicable to anesthesia practices which do not use the patient-controlled epidural analgesia technique remains to be determined.

Marcio L. Horta, Lourenço Ramos, and Zonia R. Gonçalves

The Inhibition of Epidural Morphine-induced Pruritus by Epidural Droperidol
Anesth Analg 2000 90: 638-641. [Abstract] [Full Text]  

Implications: Epidural morphine is effective for pain control but yields some side effects, including pruritus, that can be severe. Studying patients undergoing Cesarean delivery, we found a dose-related reduction in the incidence of pruritus using epidural droperidol.

REGIONAL ANESTHESIA AND PAIN MEDICINE:

Dan J. Kopacz, Hugh W. Allen, and Gale E. Thompson

A Comparison of Epidural Levobupivacaine 0.75% with Racemic Bupivacaine for Lower Abdominal Surgery
Anesth Analg 2000 90: 642-648. [Abstract] [Full Text]  

Implications: The results of this study indicate that the sensory and motor block produced by 0.75% levobupivacaine is equivalent to that of 0.75% racemic bupivacaine. Both local anesthetics are well tolerated and effective in producing epidural anesthesia for patients undergoing lower abdominal surgery.

Gerhard Brodner, Norbert Mertes, Hugo Van Aken, Thomas Möllhoff, Matthias Zahl, Stefan Wirtz, Marco A. E. Marcus, and Hartmut Buerkle

What Concentration of Sufentanil Should be Combined with Ropivacaine 0.2% wt/vol for Postoperative Patient-Controlled Epidural Analgesia?
Anesth Analg 2000 90: 649-657. [Abstract] [Full Text]  

Implications: Sufentanil is added to epidural infusions of ropivacaine 0.2% wt/vol to improve the effectiveness of postoperative pain management. Regarding the risk of side effects, however, it is still unclear what concentration of sufentanil should be added to the local anesthetic. For postoperative thoracic epidural analgesia after major abdominal surgery, the combination of ropivacaine 0.2% wt/vol and 0.75 {micro}g/mL sufentanil resulted in an appropriate cost:benefit ratio between good analgesia and side effects.

Julia E. Pollock, Dan Burkhead, Joseph M. Neal, Spencer S. Liu, Andrew Friedman, Carol Stephenson, and Nayak L. Polissar

Spinal Nerve Function in Five Volunteers Experiencing Transient Neurologic Symptoms after Lidocaine Subarachnoid Anesthesia
Anesth Analg 2000 90: 658-665. [Abstract] [Full Text]  

Implications: Electrophysiologic testing in volunteers experiencing transient neurologic symptoms is not abnormal.

D. Fletcher, M. Pinaud, P. Scherpereel, N. Clyti, and M. Chauvin

The Efficacy of Intravenous 0.15 Versus 0.25 mg/kg Intraoperative Morphine for Immediate Postoperative Analgesia After Remifentanil-Based Anesthesia for Major Surgery
Anesth Analg 2000 90: 666-671. [Abstract] [Full Text]  

Implications: The administration of 0.15 or 0.25 mg/kg perioperative morphine during remifentanil-based anesthesia for major surgery does not preclude additional morphine administration in the postanesthesia care unit. The larger dose of 0.25 mg/kg slightly improves postoperative analgesia; however, it may be responsible for postoperative respiratory depression.

Fotini Danou, Andia Paraskeva, Theodoros Vassilakopoulos, and Argyro Fassoulaki

The Analgesic Efficacy of Intravenous Tenoxicam as an Adjunct to Patient-Controlled Analgesia in Total Abdominal Hysterectomy
Anesth Analg 2000 90: 672-676. [Abstract] [Full Text]  

Implications: The preoperative administration of 20 or 40 mg IV tenoxicam does not reduce fentanyl consumption via Patient-Controlled Analgesia, compared with placebo, after total abdominal hysterectomy. Additionally, tenoxicam may increase intraoperative bleeding and gastrointestinal side effects.

Xiangqi Li and J. David Clark

The Role of Heme Oxygenase in Neuropathic and Incisional Pain
Anesth Analg 2000 90: 677-682. [Abstract] [Full Text]  

Implications: Central nervous system heme oxygenase likely plays a role in nociceptive signaling in both neuropathic and incisional models of pain. Therefore, inhibitors of heme oxygenase activity may be viable analgesics in these settings.

GENERAL ARTICLES:

Richard I. Mazze, Clair M. Callan, Susan T. Galvez, Leticia Delgado-Herrera, and David B. Mayer

The Effects of Sevoflurane on Serum Creatinine and Blood Urea Nitrogen Concentrations: A Retrospective, Twenty-Two–Center, Comparative Evaluation of Renal Function in Adult Surgical Patients
Anesth Analg 2000 90: 683-688. [Abstract] [Full Text]  

Implications: Our data for changes in serum creatinine and blood urea nitrogen indicate that, for exposures of less than 4 minimum alveolar anesthetic concentration/h, sevoflurane is not associated with an increased risk of renal toxicity compared with other commonly used anesthetics. For clinical purposes, the pre- to postoperative changes in serum creatinine and blood urea nitrogen are appropriate measures of renal function in surgical patients.

Tian J. Zhou, Jun Tang, Paul F. White, Girish P. Joshi, Ronald Wender, Mark T. Murphy, Jen W. Chiu, and Tom Webb

Reversal of Rapacuronium Block During Propofol Versus Sevoflurane Anesthesia
Anesth Analg 2000 90: 689-693. [Abstract] [Full Text]  

Implications: We studied the reversal of rapacuronium-induced block with edrophonium and found that the residual rapacuronium block can be readily antagonized during propofol-based anesthesia. However, reversal of rapacuronium appears to be less predictable during sevoflurane-based anesthesia.

Nader El-Gamal, Nabil El-Kassabany, Steven M. Frank, Ramadan Amar, Hassan Abu Khabar, Hossam K. El-Rahmany, and Ahmed S. Okasha

Age-Related Thermoregulatory Differences in a Warm Operating Room Environment (Approximately 26°C)
Anesth Analg 2000 90: 694-698. [Abstract] [Full Text]  

Implications: By increasing ambient temperature in the operating room to 26{degrees}C (79{degrees}F), the incidence of core hypothermia can be dramatically reduced in both younger and older patients.

Judith E. Hall, Toni D. Uhrich, Jill A. Barney, Shahbaz R. Arain, and Thomas J. Ebert

Sedative, Amnestic, and Analgesic Properties of Small-Dose Dexmedetomidine Infusions
Anesth Analg 2000 90: 699-705. [Abstract] [Full Text]  

Implications: The {alpha}2 agonist, dexmedetomidine, has sedation and analgesic properties. This study quantified these effects, as well as cardiorespiratory, memory and psychomotor effects, in healthy volunteers. Dexmedetomidine infusions resulted in reversible sedation, mild analgesia, and memory impairment without cardiorespiratory compromise.

Christoph H. Kindler, Christoph Harms, Felix Amsler, Thomas Ihde-Scholl, and Daniel Scheidegger

The Visual Analog Scale Allows Effective Measurement of Preoperative Anxiety and Detection of Patients’ Anesthetic Concerns
Anesth Analg 2000 90: 706-712. [Abstract] [Full Text]  

Implications: The study of qualitative aspects of anxiety reveals three distinct dimensions of preoperative fear: fear of the unknown, fear of feeling ill, and fear for one's life. Groups of patients with a higher degree of preoperative anxiety and their specific anesthetic concerns can be identified using the visual analog scale.

Robert J. Fragen and Paul C. Fitzgerald

Is an Infusion Pump Necessary to Safely Administer Remifentanil?
Anesth Analg 2000 90: 713-716. [Abstract] [Full Text]  

Implications: Because remifentanil is rapidly degraded in the body, it can be safely and effectively administered from a bag through a minidrip set. We showed that there was no difference with this less expensive method of administration than from the more precise method of a calculator infusion pump.

Kahoru Nishina, Katsuya Mikawa, Yumiko Takao, Makoto Shiga, Nobuhiro Maekawa, and Hidefumi Obara

A Comparison of Rabeprazole, Lansoprazole, and Ranitidine for Improving Preoperative Gastric Fluid Property in Adults Undergoing Elective Surgery
Anesth Analg 2000 90: 717-721. [Abstract] [Full Text]  

Implications: Acid aspiration syndrome at the induction of anesthesia is rare but still a potentially life-threatening complication. We compared rabeprazole, lansoprazole, and ranitidine for reduction of preoperative gastric fluid acidity and volume in elective surgery and found that a combination of bedtime and morning doses of rabeprazole, or a morning dose of ranitidine, similarly minimized the variables. In adult patients who are at risk of aspirating gastric contents, improvement of gastric fluid environment by rabeprazole can reasonably be anticipated to provide protection against pneumonitis should regurgitation and aspiration of gastric contents occur.

Takashi Kita, Kiyokazu Kagawa, Tadanori Mammoto, Koji Takada, Yukio Hayashi, Takashi Mashimo, and Yoshihiko Kishi

Supraspinal, Not Spinal, ₂ Adrenoceptors Are Involved in the Anesthetic-Sparing and Hemodynamic-Stabilizing Effects of Systemic Clonidine in Rats
Anesth Analg 2000 90: 722-726. [Abstract] [Full Text]  

Implications: In the regions above mesencephalon, {alpha}2 adrenoceptors were the most responsible for the minimum alveolar concentration-reducing effect and both the lower brainstem and regions above mesencephalon were involved in the minimum alveolar concentration blocking adrenergic response-reducing effect of clonidine. The spinal {alpha}2 adrenoceptors did not significantly contribute to these effects of clonidine.

John C. Dreixler, Andrew Jenkins, Ying-Jun Cao, Jeffrey D. Roizen, and Khaled M. Houamed

Patch-Clamp Analysis of Anesthetic Interactions with Recombinant SK2 Subtype Neuronal Calcium-Activated Potassium Channels
Anesth Analg 2000 90: 727-732. [Abstract] [Full Text]  

Implications: We describe differential effects of anesthetics on cloned small conductance calcium-activated potassium channels from brain that may play a role in generating the effects or side effects of anesthetics.

Sinikka Münte, Ekkehard Lüllwitz, Martin Leuwer, Bernd Mitzlaff, Thomas F. Münte, Sami Hussein, and Siegfried A. Piepenbrock

No Implicit Memory for Stories Played during Isoflurane/Alfentanil/Nitrous Oxide Anesthesia: A Reading Speed Measurement
Anesth Analg 2000 90: 733-738. [Abstract] [Full Text]  

Implications: We showed that implicit memory during general anesthesia can be abolished by changing the hypnotic anesthetic. Increased postoperative reading speed for stories presented during propofol-alfentanil-nitrous oxide anesthesia was shown in a previous experiment, but not in our study using isoflurane for balanced anesthesia.

Lionel Davis, Scott D. Cook-Sather, and Mark S. Schreiner

Lighted Stylet Tracheal Intubation: A Review (Review Article)
Anesth Analg 2000 90: 745-756. [Full Text]  

BRIEF COMMUNICATION:

Donatella De Amici, Catherine Klersy, Felice Ramajoli, and Loretta Brustia

The Awareness of Being Observed Changes the Patient’s Psychological Well-being in Anesthesia
Anesth Analg 2000 90: 739-741. [Full Text]  

TECHNICAL COMMUNICATIONS:

Donald T. Jolly and John Young

Suspected Malfunction of the SAF-T-FILL^TM Valve Assembly of the Suprane^® (Desflurane, USP) Refill Bottle
Anesth Analg 2000 90: 742-744. [Full Text]  

CASE REPORTS:

Mehmood A. Durrani and John A. Barwise

Difficult Endotracheal Intubation Associated with Torus Mandibularis
Anesth Analg 2000 90: 757-759. [Full Text]  

Ryoichi Ochiai, Junzo Takeda, Junichi Noguchi, Masahiro Ohgami, and Seiichiro Ishii

Subcutaneous Carbon Dioxide Insufflation Does Not Cause Hypercarbia During Endoscopic Thyroidectomy
Anesth Analg 2000 90: 760-762. [Full Text]  

G. Babita, T. S. Jayalakshmi, and S. Amit

Air Embolism: A Complication During Transcervical Resection of the Endometrium
Anesth Analg 2000 90: 763-764. [Full Text]  

LETTERS TO THE EDITOR:

R. Miguel, E. Fu, and Frédéric Adam

Preemptive Analgesia with Ketamine • Response
Anesth Analg 2000 90: 765. [Full Text]  

Lawrence J. Saidman, Mehernoor F. Watcha, and Paul F. White

Inappropriate Statements Can Lead to Misleading Conclusions • Response
Anesth Analg 2000 90: 765-766. [Full Text]  

Michael E. Johnson, Peter S. Hodgson, and Spencer S. Liu

Perineural Concentration of Lidocaine Is More Relevant to Spinal Neurotoxicity than the Concentration Administered • Response
Anesth Analg 2000 90: 766-767. [Full Text]  

David Warters, Stephen M. Koch, Susan Luehr, and William Knight

Thoracic Epidurals in Coronary Artery Bypass Surgery
Anesth Analg 2000 90: 767. [Full Text]  

Muhammad A. Munir, Sunder Krishnan, Mahmood Ahmad, and Stephen E. Abram

A Simple Technique to Reduce Preservative/Excipient Related Neurotoxicity of Intrathecal (Spinal) Drugs • Response
Anesth Analg 2000 90: 767-768. [Full Text]  

Robert E. Kettler, Denis L. Bourke, and Juraj Sprung

The Difficult Neuraxial Block: Predictors or Self-Fulfilling Prophecy? • Response
Anesth Analg 2000 90: 768-769. [Full Text]  

Cathy De Deyne, Raf De Jongh, René Heylen, Michel Struys, Gerard Jansen, Mohan Kedaria, Joseph Odoom, and Bas van Praagh

Jugular Bulb Desaturations During Propofol Anesthesia in Neurosurgical Procedures • Response
Anesth Analg 2000 90: 769. [Full Text]  

C. Lentschener, D. Benhamou, C. Mann, and P. Colson

Is Laparoscopic Surgery Associated with Specific Hemodynamic Changes? • Response
Anesth Analg 2000 90: 769-770. [Full Text]  

Michael J. Morrow

The Lateral Approach to the Sciatic Nerve
Anesth Analg 2000 90: 770. [Full Text]  

J. V. Llau and M. L. Garciá-Pérez

Increased Safety in the Administration of Aprotinin: Need for a Test-Dose
Anesth Analg 2000 90: 770-771. [Full Text]  

BOOK AND MULTIMEDIA REVIEWS:

Joseph M. Garfield, Jeffrey A. Grass, and Lydia Cassorla

Decision Making in Anesthesiology: An Algorithmic Approach. 3rd ed. • Spinal Drug Delivery. • Atlas of Cardiovascular Monitoring. • Books and Multimedia Received
Anesth Analg 2000 90: 772-773. [Full Text]  

ERRATA:

Correction for vol. 90, p. 482
Anesth Analg 2000 90: 516. [Full Text]  

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